Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 41 for “"Fat distribution"”.
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The Genetics of Differential Fat Distribution: The Insulin Resistance Atherosclerosis Family Study
… Although a multitude of factors contribute to fat distribution, such as age, gender, ethnicity, sex hormones, diet, and the environment, individuals of similar weights and body mass index (BMI) have large variation in the amount of VAT and SAT in their abdomen. These observations and …
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Regional Fat Distribution, Physical Activity and Hormonal Factors in Adults With Type 2 Diabetes
… study evaluated the association between central fat (CF) and both plasma hormones and physical activity (PA) in 17 men and 23 women (mean age 62 years, body mass index 31 kg/m2) with type 2 diabetes. Dual energy X-ray absorptiometry was used to assess central abdominal fat (CAF), abdominal fat …
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Functional validation of human rare missense variants associated with body fat distribution and cardiometabolic risk
Body fat distribution is a predictor of metabolic and cardiovascular disease independent of body mass index (BMI) and is heritable. To understand the genetic determinants of the differences observed in fat distribution in the general population, genome-wide association studies (GWAS) have emerged …
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Diet, Body Fat Distribution, and Serum Leptin in Young Men with Undiagnosed Obstructive Sleep Apnea Syndrome
… this study was to evaluate dietary status, body fat distribution and leptin in overweight young men with and without OSAS in comparison to published values for normal weight counterparts. Methods: Groups were comprised of 24 sedentary overweight young men with and without OSAS, who had a body …
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The relationship between high-sensitive C-Reactive Protein and the obese type by fat distribution in middle-aged Koreans
BACKGROUND AND OBJECTIVE: Obesity and metabolic syndrome are closely correlated, previous studies showed that adipocytes release many inflammatory substances. HsCRP is an indicator of an independent risk factor in coronary heart disease. And hsCRP is regulated by inflammatory factors secreted from …
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Effects of adipose tissue extracellular matrix components on body fat distribution and insulin sensitivity in black and white South African women
… of insulin resistance is android/central body fat partitioning, with visceral adipose tissue (VAT) enlargement, in particular, being closely associated with increased risk. Conversely, lower-body fat accumulation is considered to be protective. However, these relationships between body fat …
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Ethnic-specific associations between abdominal and gluteal fat distribution and the metabolic complications of obesity : implications for the use of liposuction
More than three-quarters (77%) of the 40.5 million people living in South Africa are black African, of which more than 40% are urbanised. Black African women living in urban areas have a significantly higher prevalence (62%) of overweight than urban black males (28%) or white females (53%). It was …
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Mechanism of lipid disorder in HIV infection: apolipoprotein-B kinetics, fat distribution, insulin resistance and adipocytokines in patients taking protease inhibitors or non-nucleoside reverse transcriptase inhibitors
… antiretroviral treatment of HIV infection, body fat distribution, insulin resistance (HOMA), adipocytokine and apolipoprotein-B (apoB) kinetics was investigated in 12 HIV negative controls and 55 HIV-infected patients including antiretroviral treatment-naïve patients (n=15) and patients taking …
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Ethnic specific associations between body composition and metabolic risk and the role of sex hormones and aromatase among black and white South African women
… differences in the relationship between body fat distribution and metabolic risk between black and white women. However, the reasons for these differences are not known and may be explained in part by differences in sex hormones. The overall aim of this thesis was therefore to i) examine …
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Investigating Metabolically Healthy Obesity In US Minority Populations: The IRAS Family Study
… Recent epidemiologic evidence suggests that body fat distribution and several biochemical markers may distinguish the MHO from MAO. The goal of this study is to better understand the characteristics and risk factors associated with these body size phenotypes. Specific aims for this study will be …
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Determinants of body composition changes over 5.5 years and the associated cardio-metabolic risk factors in free-living black South African women
… in body weight, body composition and body fat distribution over 5.5-years in relation to changes in cardio-metabolic risk factors; Chapter 2: To examine the modifiable and non-modifiable determinants of the changes in body weight and body fat distribution over the follow-up period. A …
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Modelling altered Glucocorticoid Sensitivity: From HPA axis to metabolic abnormalities in mice and humans
… of the HPA axis as well as the control of body fat distribution, metabolic parameters and blood pressure. Although GR deficient mouse models have been previously generated (with homozygous nulls dying at birth), the effects of altered GR density upon fat distribution and blood pressure have not …
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Novel Chemically Selective Rapid Magnetic Resonance Imaging Techniques and the Clinical Applications
… methods for the generation of high quality fat-only or water-only images in short scan durations. High quality fat imaging is mainly used for human fat distribution measurements. The study of fat distribution is important for both clinical diagnosis and basic research. The abnormal …
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Causal Gene Prioritization Across Diverse Diseases Through Multi-Omic Data Integration
… to test the role of rare coding variants using fat distribution and its effect on cardiometabolic risk as a use case, (ii) integration of proteogenomic with phenome-wide data to systematically prioritise candidate causal genes across diverse human diseases and (iii) testing the importance of sex …
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The Region Specific Influence of Estradiol on In-Vivo Lipolysis in Subcutaneous Adipose Tissue in Overweight-to-Moderately-Obese Premenopausal Women
… of adiposity in the gynoid region, a distribution which shifts towards the abdominal region after the menopausal transition. Although estrogen is implicated as a major player in determining body fat distribution the mechanisms behind estrogenic action(s) in adipose tissue of women are …
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Estrogen signaling interacts with Sirt1 in adipocyte autophagy
… Firstly, the gender difference in visceral fat distribution (Males have higher deposit of visceral fat than females) is controlled by an estradiol (E2)-autophagy axis. In C57BL/6J and wild type control mice, a higher visceral fat mass was detected in the males than in the females, which was …
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Comparison of moderate-and low-fat reduced energy diets on weight loss and body composition in post-menopausal women with android obesity
… this study was to determine if manipulation of fat content of a 1200 kcal weight reduction diet had an effect on total weight loss and fat distribution as measured by body mass index (BMI) and waist-to-hip ratio (WHR). Twenty-eight abdominally obese, postmenopausal females consumed either a 1200 …
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The influence of ethnicity, socioeconomic status and obesity intervention on body composition in UK children and adolescents
… The first study examined body dimensions and fatness in two groups of children from contrasting income backgrounds. Findings showed that children from the 'lower income’ were on average (for their age) shorter in height, heavier in weight with a higher BMI and %BF although abdominal fatness …
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The effect of an exercise intervention on insulin sensitivity, insulin secretion and insulin clearance in black obese South African women
… they exhibit lower levels of central and ectopic fat, compared to their white counterparts, contradicting the known correlates of SI typically reported in white populations. Moreover, in black African women hyperinsulinemia is in excess of the level needed to compensate for low SI, with a …
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