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Showing 1 to 20 of 802 for “"Expression levels"”.
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Quantification of the Chemotaxis Protein Expression Levels in Bacillus Subtilis
The expression levels of CheD appear to be tuned to give the functional ratio of protein need to participate in adaptation. When the potential binding partners of CheD are deleted (cheC and all ten receptors), the protein levels of CheD drop significantly. This finding suggests that B. subtilis …
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Expression levels of non-autonomous retrotransposons in germ-line rodent tissues
… RT-PCR and qPCR results suggested higher expression of both SINE and LINE elements in germ-line tissues over somatic. Additionally, the qPCR findings demonstrated higher expression of the IDL element by at least one order of magnitude than the guinea pig ID or LINE elements, relative to …
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Accurate Estimation of Isoform and Gene Expression Levels from Next Generation Sequencing Data
… as the technology of choice for performing gene expression profiling due to its wider dynamic range and digital quantitation capabilities. However, accurate estimation of expression levels from sequencing data remains challenging due to the short read length delivered by current sequencing …
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The effects of the expression levels of cellobiose transporter and β-Glucosidase on ethanol fermentation
… fermentation. In order to assess the effects of expression level of cellobiose transporter (CDT) and β-glucosidase (β-GL), in this study the copy number variation of plasmids is used to assess contributions by CDT and β-GL on cellobiose fermentation. Four different transformants contain different …
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Clinical approaches for understanding the expression levels of pattern recognition receptors in otitis media with effusion
… line of defense. In this study we evaluated the expression levels of Toll-like receptors (TLRs) -2, -4, -5, -9, and nucleotidebinding oligomerization domain-containing proteins (NODs) -1 and -2, all of which are related to bacterial infection in pediatric patients with otitis media with effusion …
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Expression levels of miRNA-127 in a cohort of HIV-positive and HIV-negative Diffuse Large B-Cell Lymphoma.
… prognosis, including miRNA-21 whose upregulated expression has been associated with bad prognosis. However, this is not specific to DLBCL and some studies done have indicated that there may be other miRNAs which are better suited to be biomarkers for DLBCL. Studies have pointed to the direction …
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Impact of environmental conditions on expression levels of resistance-nodulation-division (RND) efflux pumps and outer membrane porins in Acinetobacter baumannii
… (MDR). This organism’s ability to regulate expression of its intrinsic antibiotic resistance determinants, such as Resistance-Nodulation-Cell Division (RND) efflux pumps and outer membrane proteins, is regarded to be amongst the most important strategies in the arsenal of this pathogen. …
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Phytoplankton Response to South Louisiana Crude Oil Exposure: Determining Impacts at Individual, Community, Toxin Production, Enzymatic-Activity and Gene-Expression Levels
… community, toxin-production, enzymatic, and gene-expression levels. At the individual level, phytoplankton size influenced tolerance to crude oil, but taxonomic group seemed to be a more predominant criterion. In general, diatoms showed better tolerance to crude oil than dinoflagellates. …
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HYPOXIA-REGULATED EXPRESSION OF GLUT-1 IN GBM CELL LINES
… in relative oxygen concentration can alter gene expression in tumors to allow for their selective growth. The result of such changes allows the tumor to adapt its cellular metabolism and promote tumor progression. Most notably, hypoxic conditions induce expression of the transcription factor …
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Statistical Models for Gene and Transcripts Quantification and Identification Using RNA-Seq Technology
… on the quantification of gene and transcript expression levels. The quantification of gene expression level is a direct inference problem, whereas the quantification of the transcript expression level is an indirect problem, because the label of the transcript each short read is generated from …
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Differences in miR-122 and miR-191 Expression in HBV- versus HCV-associated Hepatocellular Carcinoma
Prior studies have suggested that the expression of miR-122 and miR-191 is decreased and increased, respectively, in hepatocellular carcinoma. However, other evidence suggests miR-122 may be preserved in HCV-associated hepatocellular carcinoma (HCC). The goal of this thesis is to assess miR-122 and …
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Study of Mutations and Expression of Genes Correlated to the Appearance of Colorectal Cancer /// Проучване на мутации и експресия на гени, корелиращи с изявата на колоректален карцином
… profile of RAS oncogene correlated to the expression levels of genes related to energy metabolism, hypoxia and genomic stability, as well as the expression levels of microRNAs and their role in regulating the previously mentioned signalling pathways in colorectal tumours. Tasks: • Analysis …
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Optimization of cDNA microarray image analysis methods
The expression of genetic information, in all organisms, might be characterized as in a constant state of flux with only a fraction of the gene within a genome being expressed at any given time. The genes’ expression pattern reflects the response of cells to stimuli that control growth, development …
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Investigation of relative expression level of SLC4 bicarbonate transporter family in mouse and Human corneal endothelial cells
… diseases in human. Aim: To characterize relative expression levels of SLC4 members in mouse and human corneal endothelium, using qRT-PCR, to identify further important members besides SLC4A11 and SLC4A4, and to explore how close to the base line levels the gene expression levels remain after cells …
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Influence of gut microbiota on immune system in infants
… correlation with immune activation is needed. Expression of genes involved in mediating and regulating immunity can be measured as an indicator of immune activity. Vaccines work by stimulating an immune response which can be measured by gene expression levels. This affects the infant's ability …
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Quantitative genetics of gene expression during fruit fly development
… in order to find loci associated with different levels of gene expression, called expression quantitative trait loci (eQTL). Because of the large amount of data that is required for such high-resolution eQTL studies, most of them have so far been carried out in humans, where the cost of data …
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Epigenetic toxicity of PFOA in HepG2 cells and its role in lipid metabolism
… vitro on the cellular, epigenetic and metabolic levels. HepG2 cells were treated with 20 μM, 100 μM, 200 μM, 400 μM PFOA dissolved in DMSO for 48 hours before harvested for DNA, RNA and assays. The mRNA expression levels of cell cycle and proliferation genes are affected significantly, as well as …
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Investigating the functionality of candidate susceptibility genes in ophthalmoplegic myasthenia gravis using patient-derived material
… myoblast cell line (C2C12, p=0.33). Next, gene expression analysis was performed in opportunistically sampled orbital fibroblasts (n=5 controls, n= 2 OP-MG) and the endogenous expression levels of ST8SIA1 was determined under basal conditions and following treatment with homologous MG sera to …
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INVESTIGATING THE FUNCTIONAL ROLES OF CRF-BINDING PROTEIN HOMOLOGUE IN THE RESPONSE TO PHYSIOLOGICAL STRESSES IN DROSOPHILA
… mammalian CRF-BP. Various stressors alter CRF-BP expression and, we observe changes in CG15537 expression coincident with the presentation of different stressors. Similar to CRF-BP expression in mammals, CG15537 is widely expressed throughout the Drosophila CNS. Furthermore, DH44 and its putative …
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