Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 196 for “"Experimental model"”.
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Exploring the Role of PANNEXIN1A in an Acute Experimental Model of Parkinson's Disease
… Pannexin1 ortholog Pannexin1a in a zebrafish model of MPTP-induced early stages of Parkinson’s disease at molecular, systems, and behavioral levels. The short-term treatment of wild-type TL and gene-edited Panx1a-KO larvae caused metabolic stress, regulated inflammatory pathways, and reduced …
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Longitudinal Metabolic and Proteomic Changes Studied in an Experimental Model of Traumatic Brain Injury
Traumatic brain injury (TBI) causes a series of complex molecular events resulting in long-term neurological deficits. Currently, it is not possible to predict which, if any, deficits might occur or when they might occur in an individual. Substantial challenges to the development of treatment …
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An investigation of the neuroprotective properties of fenamate NSAIDs, against experimental model of ischemic stroke
… volume in the middle cerebral artery occlusion model in male rats. Consistent with these results; systemic administration of mefenamic acid, by multiple intravenous injections, also reduced the ischemic damage and edema volume measured by morphometric analysis and as a function of brain water …
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Investigating the role of TREM2 and neuroinflammation in an experimental model of chronic cerebral hypoperfusion
… bilateral common carotid artery stenosis (BCAS) model of chronic cerebral hypoperfusion was implemented in wild type (WT) and TREM2-/- C57BL/6Ntac mice. Initial studies demonstrated 0.18 mm internal diameter microcoils failed to induce sufficient white matter pathology or neuroinflammatory …
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Pharmacological Investigation with Anethole in an Experimental Model of Obesity // Фармакологични проучвания с анетол в експериментален модел на затлъстяване
… orally in increasing doses to rats in a model of obesity induced by a high-calorie diet. For this purpose, 50 male Wistar rats, divided into 5 groups, consumed a high-calorie diet and were treated with three different doses of anethole for 10 weeks (65, 125 and 250 ml/kg). Behavioural, …
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Development of an experimental model to investigate the community dynamics of selected saprotrophic wood decomposer fungi from the frigate unicorn
An experimental microcosm system developed to investigate the community dynamics of two- and three-fungal species interactions is described. The microcosm consists of tessellated nutrient agar tiles allowing the varied prescription of: (1) the number of interacting fungal species; (2) the spatial …
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Evaluation of oral n-3 polyunsaturated fatty acid effect on the inflammatory response to a novel experimental model of synovitis in the horse
To view the abstract, please see the full text of the document.
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The Optimum design of Flat Rectrangular Concrete Plates supporting loads in Buidling structures and tests on a one-third full size experimental model
The popularity of concrete flat plate construction in Building Structures has soared in the last 20 years but their design has been based mainly on their ultimate strength rather than their behaviour in terms of deflection and cracking at working loads. As a result their deflections have been …
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Axotomy and Regeneration of the Rat Facial Nerve: A Histomorphometric Study of the Facial Nucleus, Nerve and Orbicularis Oculi Muscle in an Experimental Model of Facial Paralysis
… elusive. The present research utilized the rat model of facial paralysis, and consisted of three stages. Stage I examined the facial motor neuron (FMN) pool of the eye sphincter (orbicularis oculi muscle=OOM) and identified the facial nerve branch which provides the majority of innervation to …
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Study of the relationship between obesity and cardiovascular damage in an experimental model of metabolic syndrome // Изследване на връзката затлъстяване и кардиоваскуларни увреждания в експериментален модел на метаболитен синдром
… dysfunction. A promising approach is the use of experimental animal models to reproduce these alterations. The present study aims to elucidate the molecular mechanisms underlying endothelial and cardiomyocyte damage and the potential antioxidant protection, as well as to outline opportunities for …
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Mechanism of Hepatocyte Survival in Experimental Model of Non-Alcoholic Fatty Liver and Antioxidants Intake // Механизъм на хепатоцитно оцеляване при експериментален модел на неалкохолен мастен черен дроб и прием на антиоксиданти
Неалкохолната мастна чернодробна болест(НМЧБ) е най-разпространеното хронично чернодробно заболяване, свързана с нарастващата честота от затлъстяване, захарен диабет тип2, кардиометаболитни заболявания и се смята за неразделна част от метаболитния синдром. НМЧБ е клинико-патологичен синдром със …
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A Formulation for Updating Finite Element Models Through Consistent Use of Laser Vibrometer Data
… parameters in analytical finite element(FE) models using scanning laser Doppler vibrometer(SLDV) dynamic response data. The update formulation is demonstrated in several computer simulations. The formulation is the result of incorporating an analytical FE model into an experimental model. The …
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Comparative evolution of mipafox-induced delayed neuropathy in the rat and hen
… in our studies. Although the hen is the primary experimental model in the safety assessment of organophosphates, current research has suggested that the rat may have some validity as an experimental model. We examined the sequential neuropathic effects of a single dose of mipafox (30mg/kg) in …
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Analysis of a composite dielectric-ferrite loaded resonator using the transmission line model with application to a tunable dual mode bandpass filter
… wave EM simulation as well as results from the Experimental Model to insure compliance and validation. A suggestion is included to improve and modify the initial Experimental Model using the applied bias to optimize the frequency shift and bandwidth performance.
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Analysis of Origami Flasher-Inspired Deployable Structures Through Dynamic and Experimental Modeling
The Origami “flasher” model holds immense engineering promise due to its ability to alternate between a compressed 3-dimensional form and a deployed 2-dimensional form. While zero-thickness mathematical models have been thoroughly covered, dynamic modeling and material exploration are essential for …
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Forces and moments due to unsteady motion of an underwater vehicle
… to a wide range of similar shaped vehicles. The experimental model was moved in sinusoidal motion at various submergences, speeds, frequencies of oscillation, and amplitudes of oscillation.
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Evalution of a Model for Experimentally-Induced Osteoarthritis in the Hip Joint of the Dog
… the duration of the study, we conclude that the model does result in histopathologic change consistent with osteoarthritis, but that force plate analysis, radiographic evaluation, and clinical lameness evaluation are insensitive measures of this change.
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