Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"Electroretinogram"”.
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Generation of the electroretinogram M-wave and PII components in the amphibian retina
The electroretinogram (ERG) is a field potential generated by the electrical activity of the retina in response to a flash of light. The ERG is measured in humans and is useful in the diagnosis of retinal pathologies. The investigations reported in this thesis were undertaken with the expectation …
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Mechanisms of pH regulation and the generation of the electroretinogramb-wave in the toad retina
… responses of rods and Muller cells, and the electroretinogram (ERG), have been studied under various conditions.
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Clinical aspects of the electrical response of the human eye to an intense light stimulus
… Two recently discovered components of the electroretinogram are clearly shown using this technique. One of these components, the Early Receptor Potential, has not been previously described in the human eye when the work was begun.
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Modeling of phototransduction in vision systems
To improve the usefulness of the electroretinogram (ERG) in identifying the sites and mechanisms of adaptation, development and disease processes, a quantitative model was developed based on the biochemical reaction kinetics in the phototransduction cascade and experimental data. A set of …
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Spectral Sensitivity of the Goldfish ERG and Optic Tectum Before and After Optic Nerve Damage
… increment threshold procedure was used to obtain electroretinogram (ERG) and tectal responses to light onset and termination to various wavelengths of light. Spectral sensitivity functions were derived from both the ON- and OFF-components at both visual levels. By examining the spectral …
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The use of Silent Substitution in measuring isolated cone- and rod- Human ERGs
After over a decade of its discovery, the Electroretinogram (ERG) still remains the objective tool that is conventionally used in assessment of retinal function in health and disease. Although there is ongoing research in developing ERG recording techniques, interpretation and clinical …
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The use of silent substitution in measuring isolated cone- & rod- human electroretinograms. An electrophysiological study of human rod- and cone- photoreceptor activity derived using silent substitution paradigm
After over a decade of its discovery, the Electroretinogram (ERG) still remains the objective tool that is conventionally used in assessment of retinal function in health and disease. Although there is ongoing research in developing ERG- recording techniques, interpretation and clinical …
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Effects of Restricted Spectral Rearing on the Development of Zebrafish Retinal Physiology
… of retinal physiology was done by using the electroretinogram (ERG). The results showed that restricted spectral rearing caused differences in zebrafish retinal physiology. Rearing larvae in any of the constant light conditions caused deficits in sensitivity to ultraviolet and …
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Das multifokale Musterelektroretinogramm bei Patienten mit Glaukom und Neuritis Nervi Optici
Background: The multifocal pattern electroretinogram (mfPERG) allows analysis of local ganglion cell dysfunction by multifocal stimulation. Aim of this study was to investigate if this method is an useful tool for diagnosing and following glaucoma patients. Methods: Measurements on 52 age-matched …
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The Isolation of Human Rod and Cone Photoreceptor Activity combining Electroretinography and Silent Substitution Techniques
Aims: The electroretinogram (ERG) can be used to independently assess the function of rod and cone photoreceptors within the human retina. The work in this thesis sought to investigate an alternative method of recording the ERG, using the silent substitution paradigm (Estevez and Spekreijse 1982). …
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Machine Learning based Predictive Modeling of Stochastic Systems
… model for early-stage glaucoma detection using electroretinogram signals, which has been a challenging problem in ophthalmology. By leveraging medically relevant information contained in ERG signals, the study aims to establish a novel and reliable predictive framework for the early detection of …
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Study of visual field defects in patients with epilepsy receiving Vigabatrin
… visual dysfunction. The wide field multifocal electroretinogram (WF-mfERG) can objectively measure discrete areas of retinal function up to 90 degrees. The results of 204 patients with epilepsy divided into four groups are presented. A subgroup of 89 patients had repeat investigations. The …
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Myopia: structural and functional correlates
… evaluated through several vehicles: multifocal electroretinogram testing, visual field sensitivity testing, and the use of psychophysical methods to determine ganglion cell density. The results show that many quadrantic structural and functional variations exist. In general, the data could not …
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The Effect of Gonadotropin Releasing Hormone on Opsin Gene Expression and Spectral Sensitivity in Zebra Cichlid Fish (Metriaclima zebra).
… implants and intubation was investigated using electroretinogram (ERG) recordings, quantitative real-time RT-PCR and in situ hybridization. Three week and ten week sampling periods were used in the intubation study. No obvious differences in spectral sensitivity were evident when looking at …
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Determination of Chromatic and Luminance Channels in the Zebrafish Visual System Using an Increment Threshold Technique
… increment threshold procedure was used to elicit electroretinogram (ERG) b-wave responses to monochromatic light under two different intensities of white background adaptation. From the ERG b-wave responses, a spectral sensitivity function was derived under low and high levels of white background. …
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Temporal Characteristics of Zebrafish Cone Types and Their Role in Separate Visual Processing
… system to the HFP stimuli were measured by the electroretinogram. The spectral sensitivity functions of the two channels were modeled by a nonlinear regression equation to assess the relative contributions of each cone type to the spectral sensitivity functions of the two channels. In addition, …
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Characterization of Retinal Defects in Engrailed-2 Knockout (En2-/-) Mice, a Model for Autism Spectrum Disorders (ASD)
… the GABAergic interneurons marker parvalbumin. Electroretinogram (ERG) analysis revealed that the amplitude of b-wave in En2-/- mice scotoptic ERG was significantly reduced as compared with controls. Together, all these data indicate that En2-/- mice exhibit retinal defects at molecular, …
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Connexin43 as a novel therapeutic target in age-related macular degeneration
… AMD and were employed in the current study. The electroretinogram (ERG) demonstrated that photoreceptoral and postphotorecetoral functions involving both rod and cone pathways were dramatically reduced following light damage (LD) compared to normal non-LD rat eyes. Microglia activation and …
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Analysis of Zebrafish Optic Tectum Visual Processing Before and After Optic Nerve Crush
… adult zebrafish and to compare them to previous electroretinogram (ERG) spectral sensitivity data (Bilotta & Harrison, 1999). The second purpose of this study was to examine neural regeneration in the adult zebrafish at various times post-crush and to compare visual processing of these subjects …
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Zebrafish Retinal Development and the Effects of Abnormal Light Rearing Conditions
… method used to assess retinal function was the electroretinogram (ERG). Comparisons were made across the three age groups and the three conditions. Differences in the ERG waveforms and spectral sensitivities across the three ages were found. The 6-8 and 13-15 dpf subjects were less sensitive …
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