Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 104 for “"EDC"”.
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Value added by venture capitalists : the case of EDC (Export Development Canada)
… of this study is Export Development Canada (EDC), a crown corporation mandated to promote export among Canadian firms. This research finds that EDC as a VC investor and export-oriented consultant has no association with the increased probability of exporting. Also, stage of the investment …
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DEVELOPMENT OF 4'-ETHYNYL-2'-DEOXYCYTIDINE (EdC), A REPLICATION-STRESS INDUCING NUCLEOSIDE ANALOG PRODRUG WITH PREFERENTIAL ACTIVITY IN LEUKEMIA AND LYMPHOMA SUBTYPES
… we discovered 4’-ethynyl-2’-deoxycytidine (EdC) as a third-generation anticancer nucleoside prodrug with preferential activity against diffuse large B-cell lymphoma (DLBCL) and acute lymphoblastic leukemia (ALL). EdC requires deoxycytidine kinase (dCK) phosphorylation for its activity and …
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The Failure of the Proposed European Defense Community and Its Implications on the European Union's Pursuit of Strategic Autonomy
The EDC was a failed attempt at European integration in military and defense. This thesis intends to examine how and why the EDC failed and what it means for today. This thesis aims to understand what are the implications for the EDC's failure in the EU's efforts to gain strategic autonomy. This …
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Burst-mode electronic dispersion compensation in long reach PONs
… this thesis electronic dispersion compensation (EDC) techniques are employed to increase the chromatic dispersion tolerance and to enhance the system performance at the expense of moderate additional implementation complexity. In order to use such EDC in LR-PON architectures, a number of …
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Acoustic Model Adaptation For Reverberation Robust Automatic Speech Recognition
… models is performed. The reverberation model (Pw-EDC) proposed in this technique models the non-diffuse nature of the rooms. Therefore, the Pw-EDC model has dual slope energy decay where the first slope represents the steep decay of early reflections and second slope represents the slow decay of …
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Virgin Capital: Foreign Investment and Local Stratification in the US Virgin Islands
… impact of the Economic Development Commission (EDC) program in the US Virgin Islands and asks, "How do contemporary circulations of capital and people alternately build upon and complicate long-present hierarchies?" This dissertation approaches the EDC, a tax holiday program that has attracted a …
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The ecstatic display call of the Adélie penguin (Pygoscelis adeliae)
… (LMD) call and male Ecstatic Display Call (EDC). The EDC is used for both mate choice and territory defence; but apart from general structure and function this call remains basically unstudied. Therefore, the aim of this study is to examine the EDC with regard to its function (during mate …
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Extrusion and evaluation of degradation rate and porosity of small diameter collagen tubes
… hydrochloride (EDC) and Nhydroxysuccinimide (NHS) to evaluate physio-chemical properties. The samples were also evaluated for their surface area and porosity using mercury porosimeter. The noncrosslinked tubes almost completely degraded after 2 hours. The tubes …
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An integrative analysis of the multi- and transgenerational effects of endocrine-disrupting chemicals on behavior and neurobiology
Endocrine-disrupting chemicals (EDCs) are ubiquitous environmental pollutants that are known to interfere with hormone action. Exposure to EDCs during hormone-sensitive periods of prenatal development can result in disease and dysfunction later in life. Furthermore, EDC effects have been reported …
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Epigenetic Regulation of Skin Development and Postnatal Homeostasis The role of chromatin architectural protein Ctcf in the control of Keratinocyte Differentiation and Epidermal Barrier Formation
… I/II loci and Epidermal Differentiation Complex (EDC) during differentiation of the epidermis are poorly understood. By using 3D-Fluorescent In Situ Hybridization (FISH), we determined that in the epidermal keratinocytes, the KtyII and EDC loci are located closely to each other in the nuclear …
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Gradients in Collagen Films: Effects of Mechanical and Chemical Properties on Directional Cell Response
… hydrochloride with N-hydroxysuccinimide (EDC/NHS) influenced both the mechanical and chemical properties, while crosslinking using genipin altered mechanical behaviour without changing surface chemistry. By adjusting the rate of immersion and solution concentration, gradient shape could be …
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Impacto de la exposición a disruptores endocrinos a través de la alimentación en la obesidad infantil y en la microbiota intestinal
… de tóxicos llamados disruptores endocrinos (EDC) donde las moléculas tóxicas se asemejan a hormonas endógenas de nuestro organismo, mimetizando su modo de acción. Estos son EDC son bioacumulables, de exposición ubicua y continua, de transferencia generacional y tienen un efecto coctel que …
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Enterprise performance measurement system : metric design framework and tools
… Aerospace Engineering Development Center (STA EDC) is the enterprise involved in action research, the research methodology used in this work. The background of STA EDC is included to provide the context and purpose. There are four major action research cycles including EPMS Ten Lenses (cycle …
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Britain, France and the Rearmament of the Federal Republic of Germany 1947 - 1954: Cooperation and Discord
… for a European Defence Community (EDC), was an attempt to save the Schuman Plan and France's bid to define West Germany's role in Europe. Due the Britain's reluctance to reconcile her atlanticist tendencies with the French vision for Europe, Britain stayed out of the French plan. …
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Public awareness and risk perceptions of endocrine disrupting chemicals
Endocrine disrupting chemicals (EDCs) are exogenous chemicals found in food, consumer products, and the environment. EDCs are ubiquitous in modern life and human exposure is associated with many negative health effects such as reproductive disorders, metabolic disorders, and hormone related …
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Lipoprotein Subclass Measurements by an Updated Nuclear Magnetic Resonance Spectroscopy Method in the Prediction of Coronary Artery Disease in Type 1 Diabetes
… Epidemiology of Diabetes Complications study (EDC) cohort, coronary artery disease (CAD) case-control study in 142 study participants2, 3, 4, 5, 6, 7. Findings in this paper showed that increased large HDL particle concentration by NMR was related to a decreased CAD risk while medium HDL …
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Evaluation of effect of extrusion process variables on mechanical properties of extruded collagen tubes and effect of post extrusion treatments
… study, are crosslinking by glutaraldehyde and EDC/NIHS. Result of these studies showed that, crosslinking with glutaraldehyde gives higher degree of crosslinking than EDC/NHS; and the coagulation with acetone and ammonium hydroxide is also more effective than coagulation with just ammonium …
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Design and Analysis of a Collagenous Anterior Cruciate Ligament Replacement
… 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) were investigated as possible crosslinking methods for the scaffolds, and EDC crosslinking was deemed more appropriate given the gains in strength and stiffness afforded to individual collagen fibers. Scaffolds were composed of 54 collagen …
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THE INTERGENERATIONAL IMPACT OF ENVIRONMENTAL EXPOSURES: MOLECULAR INSIGHTS FROM MODELLING PLURIPOTENCY TRANSITIONS THROUGH THE HUMAN GERMLINE
… impact of endocrine disrupting chemicals (EDCs), widespread compounds that interfere with hormonal signalling causing several adverse health effects. To overcome these challenges, I first implemented in the lab publicly available protocols to differentiate human induced pluripotent stem …
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Understanding Non-Plume Related Intraplate Volcanism
… delamination, and edge driven convection (EDC), could be responsible for magmatism. This dissertation explores intraplate volcanic locations that do not fit the mantle plume model, and presents geochemical evidence for lithospheric delamination and edge driven convection for the cause of …
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