Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 402 for “"DNA sequence"”.
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Some Probability Methods For DNA Sequence Analysis
… employed in the analysis of data emerging from DNA sequence studies. To sequence DNA sequences, one of the methods employed is to sequence overlapping fragments of the DNA. These overlapping fragments form a contig. In this thesis, probability methods to study the mean number of contigs and mean …
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RNA and DNA Sequence Analysis of the Human Transcriptome
… part by gene expression, or the transcription of DNA into RNA. As such, the study of the transcriptome, or the characterization and quantification of all RNA produced in the cell, is important. Recent advances in sequencing technology have allowed for unprecedented interrogation of the …
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Scaling short read de novo DNA sequence assembly to gigabase genomes
… new technologies sample much shorter segments of DNA, called short reads, than conventional but more costly long read sequencing technologies, and suffer from higher and more varied error rates. Modern genome assembly tools compensate for these shortcomings by using de Bruijn graph based assembly …
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Influence of DNA sequence context on O⁶-methylguanine mutagenicity in Escherichia coli
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1999.
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Mitochondrial DNA sequence variation in North Atlantic long-finned pilot whales, Globicephala melas
I sequenced mitochondrial DNA (mtDNA) from 59 long-finned pilot whales (Globicephala melas) that stranded on the coasts of Cape Cod, Newfoundland, Nova Scotia, Scotland, and England or were caught by commercial fisheries operating in the western North Atlantic, to determine if there is more than …
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Investigations of DNA sequence content and context effects on DNA stability and reactivity.
Investigations of DNA sequence content and context effects on DNA stability and reactivity.
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Mitochondrial DNA Sequence Variation in Populations of the Nine-Banded Armadillo (Dasypus novemcinctus)
… Arkansas and central Texas). A 233 basepair sequence of the D-loop region of mitochondrial DNA was sequenced in individuals from each population. Individuals and populations were compared to assess relatedness among populations and individuals. Higher sequence diversity was detected in the …
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Improved GPU implementations of the Pair-HMM forward algorithm for DNA sequence alignment
The student, Enliang Li, accepted the attached license on 2021-04-30 at 13:30.
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Mitochondrial DNA sequence variation in North Atlantic long-finned pilot whales, Globicephala melas
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1994.
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Comparative Mitochondrial DNA Sequence Diversity in Isolated and Open Populations of Southern Flying Squirrels
… nucleotide hypervariable region of mitochondrial DNA was sequenced in individuals from each population. Individuals and populations were compared to assess relatedness. Higher sequence diversity was detected in the open and island populations. One island individual shared characters with both the …
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Molecular Comparisons of Colicin Ia and Colicin Ib (Dna Sequence, Secondary Structure, Immunity Genes)
Colicin Ia and colicin Ib have three distinct functional characteristics, receptor specificity, mode of action and immunity recognition. Both colicins bind to the same receptor and kill sensitive Escherichia coli cells by depolarizing the cell membrane. Sensitive cells carrying the colicin Ib …
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The role of DNA sequence during helicase loading at S. cerevisiae origins of replication
Eukaryotic chromosomal DNA replication is a tightly regulated process that initiates at multiple origins of replication throughout the genome. As cells enter the GI phase of the cell cycle, the Mcm2-7 replicative helicase is loaded at all potential origins of replication but remains inactive until …
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DNA sequence design of non-orthogonal binding networks, and application to DNA data storage
DNA has proven itself a powerful tool in a diverse array of nanotechnology-related domains, including molecular computation, nanostructure fabrication, and data storage. Most DNA-based systems focus on using sets of DNA sequences that are orthogonal to each other, such that each DNA sequence has a …
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Label-free DNA Sequence Detection Using Oligonucleotide Functionalized Fiber Probe with a Miniature Protrusion
DNA is the substance that encodes the genetic information that cells need to replicate and to produce proteins. The detection of DNA sequences is of great importance in a broad range of areas including genetics, pathology, criminology, pharmacogenetics, public health, food safety, civil defense, …
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Characterization, purification, and DNA sequence analysis of a novel ATPase of the archaebacterium Methanococcus voltae
Membrane-bound ATPase activity was detected in the methanogen Methanococcus voltae. The ATPase was inhibited by vanadate, a characteristic inhibitor of the P type ATPases. The enzyme activity was also inhibited by diethylstilbestrol. However, it was insensitive to …
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Assessment of species boundaries of the Moringa Ovalifolia (Dinter & A. Berger) in Namibia using nuclear its DNA sequence data
… the nuclear Internal Transcribed Spacer (ITS) sequenced data analysis. A total of seventeen (17) edited sequences of M. ovalifolia together with thirteen (13) other sequences of Moringa retrieved from NCBI were used to construct phylogenetic trees in Molecular Evolutionary Genetic Analysis …
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An investigation of DNA sequence variants in genes that regulate collagen fibrillogenesis and predisposition to musculoskeletal soft tissue injuries
The aim of this dissertation was to use a case-control genetic study to investigate the association of polymorphisms within the COL5A1, MIR608, COL11A1 and COL11A2, genes with AT and/or ACL injuries in Caucasian populations. These aims were explored in three studies: i) Determine whether the COL5A1 …
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A pathway-based approach investigating DNA sequence variants to implicate the inflammatory pathway in the predisposition to Achilles tendinopathy
The aims of this dissertation were therefore (i) to follow a pathway-based approach investigating genes encoding proteins involved in the ECM degradation and apoptosis signalling cascade for associations with AT and (ii) to identify a polygenic risk model, comprised of several genetic markers …
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DNA Sequence and Haplotype Variation Analysis of Inflammatory Response Genes NLRX1, IL6, and IL8 in the Turkey (Meleagris gallopavo)
… the genomic level. To test the hypothesis that DNA sequence variations in inflammatory response genes are associated with phenotypic differences in the heritage turkey, the primary objective of this project was to search for single nucleotide polymorphisms (SNPs) in candidate inflammatory …
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