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Showing 1 to 12 of 12 for “"DMPO"”.
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DNA-Schädigung durch photochemische Alkoxylradikalquellen
… die EPR-spektroskopisch durch Spinabfang mit DMPO als DMPO-OtBu-Addukt nachgewiesen werden. In wässrigem Medium, unter Ausschluss von molekularem Sauerstoff werden zusätzlich DMPO-Addukte von Methylradikalen (DMPO-Me) detektiert. Mit abnehmender Konzentration an eingesetztem DMPO entsprechen …
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Insights into the radiation Chemistry of FLASH Radiation Therapy
… radiation chemistry studies, the spin trap DMPO was used to detect hydroxyl radicals (•OH) and hydrogen radicals (•H) in normoxic triple-distilled water. Irradiations were performed using a modified Varian Clinac 21X. Spin adducts (•DMPO-OH, •DMPO-H) were quantified via electron paramagnetic …
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Molecular basis of MPTP-induced Parkinson's disease
… using 5, 5-dimethyl-1-pyrrolonine-N-oxide (DMPO) as the spin trapping agent. The rate of formation of spin adduct (DMPO-O₂⁻) was dependent not only on the concentrations of MPDP⁺ and oxygen but also on the pH of the system. Superoxide dismutase inhibited the spin adduct formation in a …
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Quantum Yields And Mechanism In Titanium Dioxide Mediated Photocatalysis
… the spin trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO), for the measurement of growth rates of the spin adduct DMPO-OH and HPLC measurement for the {dollar}cdot{dollar}OH radical generation rates. The agreement of the trapping efficiency (0.33 {dollar}pm{dollar} 0.04) in the homogeneous …
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Synthèse de Nouvelles Nitrones du Type Pyrroline-N-Oxyde et leur Utilisation en Spin-Trapping
… au 2,2- diméthyl-3,4-dihydro-2H-pyrrole-1-oxyde (DMPO) couramment utilisé : meilleure persistance de l'adduit du superoxyde DEPMPO-OOH, absence de décomposition spontanée de cet adduit en l'adduit DEPMPO-OH, moindre sensibilité à l'addition nucléophile de l'eau. Ces caractéristiques sont liées à …
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Effects of taurine and hypotaurine on oxidative lung injury
… EPR study using 5,5-dimethyl-l-pyrroline-Noxide (DMPO) as a spin trap, both taurine and hypotaurine caused dose-dependent inhibition of DMPO-OH and DMPO-OOH adduct formation. In the ex vivo rat lung model, the addition of 5 and 10 mM taurine to the perfusion medium 20 minutes prior to the …
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Formation and Stabilization of Combustion-Generated Environmentally Persistent Free Radicals on Transition Metal Oxides Supported on Silica
… higher than in serum. On average, twice as much DMPO-OH spin adducts was formed in the presence of EPFR-containing particle compared to non-EPFR-containing particles at higher incubation time. A 10:1 ratio of OH radical concentration formed to the number of EPFR radicals indicates a cyclic …
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Hydroxyl Radical Production via Acoustic Cavitation in Ultrasonic Humidifier Systems
… the systems. Hydroxyl radicals were found using DMPO as a spin trap. Caffeine and 17β-estradiol, as pharmaceutical contaminants of drinking water, were both emitted from the humidifier when present in the water reservoir and would enter breathing air. Emitted 17β-estradiol was found at 60% of the …
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Recherche et synthèse d'un piège à radicaux libres d'interet biologique: le (5-méthyl-1-oxyde-D-1-pyrrolin-5-yl) méthyl phosphonate diéthylique
… superoxyde) s'avèrent supérieures à celles de la DMPO couramment utilisée. Dans le but de mieux cerner l'influence du groupement phosphoryle sur ces réactions de piégeage et sur la durée de vie des adduits, nous avons entrepris de synthétiser le (5-méthyl-1-oxyde-Δ-1-pyrrolin-5-yl) méthyl …
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Computational Investigation of Spin Traps Using Hybrid Solvation Models.
… cyclic nitrone 5,5-dimethyl-1-pyrroline-N-oxide (DMPO), and the lesser known linear phenyl-N-tert-butylnitrone (PBN) and its phosphorylated analogues have been used as spin traps for the investigation of free radicals in biological systems. Theoretical work on these molecules suggests that there …
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DISINFECTION USING A NOVEL HETEROGENEOUS CATALYST
… Electron paramagnetic resonance studies using DMPO as radical scavenger indicated that PCat decomposes H2O2 to generate hydroxyl radicals (.OH radicals). .OH radicals were seen to be involved in the mode of antimicrobial action. These studies have demonstrated the potential biocidal use of the …
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Oxidative DNA-Schädigung durch elektronisch angeregte Carbonylverbindungen und daraus gebildete Radikalspezies
… durch Spinabfangexperimente mit DMPO und TEMPO belegt werden. Im Fall von AP-OMe wurde weder dessen Triplettzustand noch die Bildung von Radikalen detektiert, was auf einer schnell ablaufenden Norrish-Typ-II-Spaltung beruht. Aufgrund dieses photochemischen Verhaltens wurden die …