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Showing 1 to 17 of 17 for “"DIDS"”.
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Validation of the Disability Identity Development Scale Among Student Veterans With Disabilities in Higher Education
… of the Disability Identity Development Scale (DIDS) among a sample of student veterans with disabilities in higher education. The primary objectives were to replicate the factor structure of the DIDS, evaluate its internal consistency reliability, and explore its relationship with other scales, …
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Evaluation of Anion Transporters as Potential Target Sites for Insect and Nematode Control: Toxicological, Electrophysiological, and Molecular Studies
… study, four anion transporter (AT) blockers, DIDS (4, 4′-diisothiocyanatostilbene-2, 2′-disulfonic acid), 9-AC (anthracene-9-carboxylic acid), NPPB (5-nitro-2-(3-phenylpropylamino) benzoic acid), and IAA-94 (indanyloxy acetic acid) were selected to evaluate ATs as potential target sites for …
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The modulation of autoimmune disease progression in mouse models
… acid, also known as DIDS, is a small molecule that inhibits HR pathway and subsequently leads to apoptosis of class switching cells. DIDS treatment remarkably retarded the progression of TID, even when started at a relatively late stage, indicating the potential of …
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TGF-β1-induced Chloride Channel Activity and Migration of Human Eosinophils
… 4’-diisothiocyanatostilbene-2,2’-disulfonic acid (DIDS) and 5-nitro-2-(3-phenylpropylamino)benzoic acid (NPPB). Protein expression of the chloride channel (CLC) family of chloride channels, PKC isozymes, and Smad transcription factors was determined using western blot, and mRNA expression of CLC …
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Understanding resilience in college students with disabilities: an explanatory sequential mixed methods study
… and disability identity development (DIDS) and demographic information, including about their specific disability. Then, participants who scored in the high (+1 SD) or low (-1 SD) resilience groups and were interested in interviewing were considered for Phase Two. 270 participants …
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Toxicological Analysis of Acaricides for Varroa Mite Management
… of acaricide resistance. The stilbene product DIDS had significantly higher field efficacy to acaricide-resistant mites compared to Apistan®- and CheckMite+®. These data suggest that DIDS, and other stilbene products, might serve as candidate chemistries to continue field efficacy testing of …
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Gastrointestinal (GI) Motility is Unaltered by Feeding in Zebrafish
… and interval. The effects of Niflumic Acid and DIDS were also examined, because anoctamin 1 (ANOl), a chloride-selective channel, has recently been identified as a potential regulator for ICC pacemaker function. Both drugs dramatically reduced the total number of contractions as well as the GI …
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Dilution acidosis : the effects of hyperosmolality on acid-base balance and ventilation
… However, both the anion-exchange blocker DIDS and the Na+/H+ exchange blocker amiloride reversed the intracellular pH change from alkalosis to acidosis, although they did not affect the extracellular acidosis caused by acute hyperosmolality. These results indicated that hyperosmolality …
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Die Regulation des Na+2Cl-K+-Cotransporters in der basolateralen Membran der Rattenkolonkrypte
… Der HOE 694-hemmbare Na+/H+-Austauscher und der DIDS-hemmbare, Na+-abhängige HCO3-/Cl--Austauscher führen durch pH-Gegenregulation unter NH3/NH4+-Gabe zu einer Verminderung der langsamen Azidifizierungsrate. <br>Aufgrund dieser Befunde wurde der Azosemid-hemmbare Anteil der langsamen …
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Die pH-Regulation isoliert in vitro perfundierter Kolonkrypten der Ratte
… für EIPA bzw. HOE694 0,2 bzw. 2 µmol/l) und als DIDS-hemmbarer und Na+-abhängiger HCO3--Import charakterisiert. Experimente mit veränderten Triebkräften für Cl- wiesen darauf hin, daß es sich bei diesem Transporter wahrscheinlich um einen elektroneutralen Na+-abhängigen HCO3-/Cl- Austauscher …
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Estudio toxicológico y electrofisiológico de ficotoxinas marinas: Mecanismo excitotóxicos y apoptóticos en cultivos primarios de neuronas
… de toxicidad diferente que no fue prevenido por DIDS ni implicó procesos apoptóticos. El estudio del sinergismo entre PlTX y DOM mostró que concentraciones no tóxicas de PlTX indujeron un incremento de los niveles de ARNm que codifican genes de expresión rápida (IEGs), alcanzando su pico máximo a …
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Mechanisms of ion channel activation in primary cultured and clonal cell lines
… by the chloride channel inhibitors NPPB and DIDS but resistant to DPC. A Cl- conductance with similar characteristics was found to be present in mouse primary cultured calvarial osteoblasts. The volume-sensitive Cl- current in ROS 17/2.8 cells was inhibited by arachidonic acid in two distinct …
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Elektrophysiologische Untersuchungen an einzelligen marinen Riesenalgen
… wie TEA (Tetraethylammonium), Ba2+ und DIDS (4,4'-Diisothiocyanatostilben-2,2'-Disulfonsäure), nur die schnelle Relaxation des Ladungspulsspektrums, nicht aber die langsame. Dagegen hatte die Zugabe dieser Inhibitoren zu der vakuolären Perfusionslösung keinen signifikanten Einfluss auf …
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Nongenomic Effects of Estrogens on Epithelial Chloride Secretion.
… is not blocked by the chloride channel blockers DIDS and NPPB but is abolished by the PKA inhibitor H89, suggesting that 17β-E2 potentiation depends on the activity of CFTR but not other types of apical membrane chloride channels. 17β-E2 does not increase the activity of calcium-activated …
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Strukturelle und biochemische Charakterisierung der humanen löslichen Adenylyl-Cyclase
… 4,4'-Diisothiocyano-2,2'-stilbendisulfonsäure (DIDS) hingegen inhibiert die hsAC durch Bindung im Zugang zum aktiven Zentrum und verhindert damit auch eine Aktivierung durch Bicarbonat. Zusätzlich wird das Arg176 blockiert, welches essentiell für die Bicarbonataktivierung ist. Zusammenfassend …
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Aspects of purine and pyrimidine metabolism
… of transport by the specific band 3 inhibitors DIDS and CHCA confirm that transport is via the band 3 anion transporter. This explains the lack of significant uptake of orotate by most differentiated tissues which lack the intact band 3 protein. However, the demonstration of band 3 in rat …