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Showing 1 to 13 of 13 for “"CcpA"”.
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CcpA-Mediated Carbon Catabolite Repression of Virulence in the Group A Streptoccus
… regulation, carbon catabolite control protein (CcpA), in the regulation of virulence of the GAS. A putative CcpA-binding site or catabolite response element (cre) was identified upstream of the promoter for the virulence gene regulator, Mga. CcpA was shown to specifically bind to this cre, and …
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The Role of CcpA in Regulating the Carbon-Starvation Response of Clostridium perfringens
… requires the transcriptional regulator CcpA, mediator of catabolite repression. Sporulation is repressed by glucose, but, surprisingly, in a CcpA-independent fashion. C. perfringens cells in a biofilm are resistant to a number of environmental stresses, including oxygen and antibiotics. …
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Regulation of phoPR and cydABCD promoters of Bacillus subtilis by catabolite control protein A (CcpA).
… subtilis by catabolite control protein A (CcpA).
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Characterization of the Components of Carbon Catabolite Repression in Clostridium perfringens
… a complex with the transcriptional regulator CcpA to regulate transcription. We were able to show here that purified recombinant C. perfringens HPr kinase/phosphatase was able to phosphorylate the serine-46 residue of HPr. When the codon for this serine residue is mutated through PCR …
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Investigation of carbon catabolite repression in Clostridium beijerinckii NCIMB 8052
… by a protein of the GalR-LacI family, the CcpA protein. A ccpA homologue, regA, has been previously identified in C. acetobutylicum NCP262 and successfully complemented a B. subtilis ccpA mutant strain. The sucrose operon from C. beijerinckii NCIMB 8052, scrARBK, has been characterised at …
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Crystallographic studies on diheme cytochrome <i>c</i> enzymes
… Funktion der periplasmatischen c-Typ Cytochrome CcpA und MacA des δ-Proteobakteriums Geobacter sulfurreducens aufzuklären und beide Proteine biochemisch wie auch strukturell zu charakterisieren.Bakterielle Cytochrom c Peroxidasen sind eine weit verbreitete Familie von periplasmatischen Enzymen, …
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Intra-nacc adenosine and its role in mediating palatable food intake: interactions with striatal opioids
… The influence of the A1 receptor agonist CCPA, the A1 receptor antagonist DPX, the A2A receptor agonist CGS 21680, and the A2A receptor antagonist MSX-3 on feeding behaviors was investigated. CCPA had no effect on baseline or DAMGO-induced feeding or activity, while CGS 21680 decreased …
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The Design and Synthesis of Autotaxin Inhibitors and Analogs of Lysophosphatidic Acid
… explores the synthesis of the stereoisomers of 3‑CCPA and the pharmacological activites of these isomers. Chapter 3 discusses the design and synthesis of benzyl and naphthalene-methyl phosphonic acid inhibitors of autotaxin with anti‑invasive and anti-metastatic actions. Chapter 4 elaborates on …
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A Practical Approach to Federated Learning
… government regulations such as GDPR, HIPPA, and CCPA restrict how organizations can share data with other entities. This forces organizations with sensitive datasets to develop models that are only locally optimal. Federated learning (FL) facilitates robust machine learning by enabling the …
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Canonical Correlation and Correspondence Analysis of Longitudinal Data
… (CA) is used. Canonical correspondence analysis (CCPA) is used to deal with the case when one set of variables is categorical and the other set is quantitative. By exploiting the interrelationships between these three techniques we first provide a theoretical basis for CCPA.</p> <p>Next, in this …
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Flexible Privacy via Disguising and Revealing
… to delete their data (via e.g., the GDPR or CCPA), more nuanced data controls often don’t exist. For example, a user might wish to hide and protect their profiles on an e-commerce or dating app when inactive, and to recover their accounts should they return to the application. However, …
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Sex differences in the cardiac beta-adrenergic receptor contractile response
… investigated using the A<sub>1</sub>AR agonist CCPA and A<sub>1</sub>AR knockout (KO) mice. Intact females showed an enhanced A1AR anti-adrenergic effect compared to males and ovariectomized females. The &beta-adrenergic contractile response was potentiated in male and female A<sub>1</sub>ARKO …
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Transcriptional Regulation of the MGA Virulence Regulon in Streptococcus Pyogenes
… An EMSA with the catabolite control protein (CcpA) verified its ability to bind specifically to this site. Further, a deletion of the cre site in the context of the whole promoter as well as with respect to its upstream transcriptional start site determined that the cre site is necessary for …