Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 39 for “"CTB"”.
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Control of the CTB-SPSC
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2027-08-01
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The Role of TGF-β in CTB-Insulin Regulated Human Dendritic Cell Tolerance
… to autoantigen vaccines such as proinsulin (CTB-INS) down regulates dendritic cell (DC) activation and induces the synthesis of DC immunosuppressive cytokines. Recent studies of CTB-INS induction of immune tolerance in human DCs indicate that increased IDO1 biosynthesis may play an important …
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Validity and Diagnostic Accuracy of a Clinical Trial Battery for Primary Brain Tumor Patients
… tumor patients. The Clinical Trial Battery (CTB) consisting of the Hopkins Verbal Learning Test-Revised, Trail Making Test, and Controlled Oral Word Association is currently in use for multinational / multisite clinical trials of primary brain tumor patients. Although the CTB is brief, …
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Use of the Clegg Impact Soil Tester to Access Rutting Susceptiblity of Cement-Treated Base Material Under Early Trafficking
… of early-age damage, cement-treated base (CTB) materials must be allowed to cure for a period of time before the pavement can be opened to traffic. Trafficking of a CTB before sufficient strength gain has occurred can lead to marring or rutting of the treated layer. The specific objectives …
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Plant-delivered Cholera Toxin B subunit as an Immunomodulatory Molecule
<p>The B subunit of cholera toxin (CTB) functions as an effective mucosal carrier molecule of chemically or genetically conjugated antigens. Orally delivered CTB or CTB fusion protein binds to G<sub>M1</sub>-ganglioside receptor molecules located on cells in the gutassociated lymphoid tissues, the …
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Use of Cholera Toxin B as a Vaccine Adjuvant Activates Antigen Presenting Cells and Stimulates Production of Pro-Inflammatory Cytokines
… adjuvanted with Cholera toxin “B” (CTB), successfully granted full protection against a less virulent strain (<em>FT LVS</em>) of the bacterium and provided partial protection against a more virulent strain (SchuS4). However, the mechanisms of this protection are not fully …
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Receptor Mediated Oral Delivery Of Bioencapsulated Green Fluorescent Protein Expressed In Transgenic Chloroplasts
… transmucosal carrier cholera toxin B subunit (CTB), a CTB-GFP fusion protein separated by a furin cleavage site was expressed via the tobacco chloroplast genome and used as a visible marker. Site specific integration of the transgene was confirmed by PCR analysis. Southern blot analysis …
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Cracking and Roughness of Asphalt Pavements Constructed Using Cement-Treated Base Materials
… shrinkage strains in the cement-treated base (CTB) that can lead to reflection cracking in asphalt surfaces. Cracking may then cause increased pavement roughness and lead to poor ride quality. The overall purpose of this research was to utilize data collected through the Long-Term Pavement …
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Estudio de la disfunción mitocondrial placentaria en el embarazo complicado con preeclampsia mediante un modelo celular trofoblástico
… celulares del trofoblasto: el citotrofoblasto (CTB) y el sincitiotrofoblasto (STB). Para ello, como muestras se utilizaron explantes de placenta de embarazos a término mediante cesárea, tanto control como con PE, muestras de sangre de las embarazadas, fracciones mitocondriales enriquecidas de …
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cholera Toxin B Subunit-Diabetes Autoantigen Fusion Proteins Modulate Dendritic Cell Function and T Cell Morphogenesis
… as the non-toxic cholera enterotoxin B subunit (CTB). To identify mechanisms responsible for CTB-autoantigen fusion protein suppression of diabetes autoimmunity, dendritic cells (DCs), a major class of antigen presenting cells (APC) involved in restoration of immunological tolerance, were …
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Mechanism of Chimeric Vaccine Mediated Immune Suppression of Human Dendritic Cells
… a mucosal adjuvant the cholera toxin B subunit (CTB-INS). Proteomic analysis of vaccine inoculated DCs revealed strong up-regulation of the tryptophan catabolic enzyme indoleamine 2, 3-dioxygenase (IDO1) shown to be directly linked to CTB-INS-induced DC activation and maturation. Treatment of …
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Early Age Assessment of Cement Treated Materials
… of early-age damage, cement-treated base (CTB) materials must be allowed to cure for a period of time before the pavement can be opened to traffic. The purpose of this research was to evaluate the utility of the soil stiffness gauge (SSG), heavy Clegg impact soil tester (CIST), portable …
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Foraminiferal and stable isotope investigation of the Cenomanian-Turonian extinction and oceanic anoxic event
… around the Cenomanian-Turonian Boundary (CTB) (93.5 Ma). The mid-Cretaceous is considered to mark a period of intense global warming related to widespread tectonic activity, leading to periods of high sea level and no polar ice. This had great effects on the ocean's structure, chemistry …
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Plant-based Multicomponent Vaccines against Enteric Diseases
… was linked to the cholera toxin B subunit (CTB) and the ETEC fimbrial antigen CFA/I was linked to the cholera toxin A2 subunit. Cholera toxin-antigen fusion proteins were detected in transformed tuber tissues by immunoblot assay and quantitated by enzyme linked immunosorbent assay (ELISA). …
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Expression Of Cholera Toxin B Subunit-rotavirus Nsp4 Enterotoxin Fusion Protein In Transgenic Chloroplasts
… linked to rotavirus enterotoxin 90 aa protein (CTB-NSP490) was introduced into transgenic chloroplast and was transformed into chloroplast genome of Nicotiana tabacum by homologous recombination. The chloroplast integration of CTB-NSP4(90) fusion gene was confirmed in transgenic tobacco plants …
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Utilization of Cholera Toxin B as an Adjuvant for the Subunit PspA Vaccine, Provides Effective Protection against Streptococcus pneumoniae Challenge
… protection, this study utilizes Cholera Toxin B (CTB) as an adjuvant to effectively increase vaccine efficacy. We assessed the efficacy of the subunit vaccine, PspA, administered intranasally (i.n.) in conjunction with CTB as an adjuvant. Our results indicated increased survival in mice immunized …
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The diagnostic yield of computerised tomography in human immunodeficiency virus (HIV) positive psychiatric patients at a tertiary hospital in the Western Cape
… To determine the diagnostic yield of CT brain (CTB) scans in HIV+ psychiatric patients and to describe these abnormalities as well as demographic and clinical variables associated with abnormal CT scans. Methods. A retrospective study was conducted at the Department of Psychiatry and Mental …
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Strategies for the induction of mucosal immunity against hepatitis B virus.
… enterotoxin (LT), the B subunit of CT (CTB) and a non-toxic derivative of LT (LTK63) was evaluated with intranasal delivery. We also evaluate the potential of administering immunostimulatory complexes (comprised of HBsAg complexed with antibodies against HBsAg) by a mucosal route and …
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Spinal interneurons in sensorimotor integration
… the first aim, the B-subunit of cholera toxin (CTb) was injected into the motor nuclei at the L1 or L3 segmental level to retrogradely label propriospinal interneurons in the L5 segment of rat spinal cord. These cells had a clear distribution pattern which showed that they were located mainly in …
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Magnetic Resonance Studies of the Diffusion Dynamics of Molecular Systems Relevant to Fischer-Tropsch Catalysis
… heavy liquid product. The Cohen-Turnbull-Bueche (CTB) free volume model of diffusion is shown to be an accurate description of the diffusion of liquid hydrocarbon products. As such, a novel optimisation method is developed that is able to calibrate the model when applied to hydrocarbon mixtures …
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