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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 93 for “"CLL"”.

  1. Bedeutung von SNPs im Krankheitsverlauf der CLL

    Pfeiffer, CarolinUniversität Ulm

    ulm-diss Repository record

  2. Analysis of the Tumour Microenvironment in CLL

    Hamilton, EmmaKing's College London2013

    … systems in Chronic Lymphocytic Leukaemia (CLL).CLL is a cancer of the blood which affects B cells. CLL cells accumulate quickly in the body but die rapidly by apoptosis when cultured in the lab, suggesting that CLL cell survival can be modulated by tumour cell interactions with the …

    kings Repository record

  3. Two-Stage Multi-Channel LED Driver with CLL Resonant Converter

    Chen, XuebingVirginia Tech2014

    … stage and a multi-channel constant current (MC3) CLL resonant converter as the second stage. For the CLL resonant converter, the magnetizing inductance of the transformer can be as large as possible. Therefore, the magnetizing current of the transformer has little influence on the output currents. …

    vt Repository record

  4. Prognostische und prädiktive Bedeutung von Mutationen der nicht-codierenden 3‘ Region im NOTCH1 Gen bei der CLL : Eine Untersuchung im Rahmen der CLL11 Studie der Deutschen CLL Studiengruppe

    Geppert, MartinUniversität Ulm

    ulm-diss Repository record

  5. Untersuchung der Wirkung des Inhibitor of Apoptosis Antagonisten BV6 auf primäre CLL Zellen

    Dodier, DagmarUniversität Ulm

    ulm-diss Repository record

  6. Entwicklung von GM-CSF-produzierenden EBV-Vektoren für die Immuntherapie der B-CLL

    Hellebrand, EvaLudwig-Maximilians-Universität

    … Zytokin GM-CSF in Tumorzellen von B-CLL-Patienten (Chronische lymphatische Leukämie) exprimieren. Dabei entscheidend ist die Eigenschaft von EBV naive, wie auch reife und maligne B-Lymphozyten über den CD21-Rezeptor spezifisch zu infizieren. Als Grundlage diente das Maxi-EBV-System, …

    lmu-germany Repository record

  7. The expression and signalling patterns of CD180 toll like receptor in Chronic Lymphocytic Leukaemia (CLL)

    Sayed, U.University of Westminster2019

    Chronic lymphocytic leukaemia (CLL) is characterised by a progressive accumulation of mature CD5+CD20+CD23+ lymphocytes. Despite the remarkable progress in our understanding of the immunobiology of CLL, the aetiology of the disease remains unknown. The consensus is that CLL cells are driven by …

    westminster Repository record

  8. Cll Metabolism Is Regulated By Prognostic Factors, Modulated By Stroma and Abrogated By Pi3K Inhibition

    Vangapandu, Hima2017

    <p>Metabolism of chronic lymphocytic leukemia (CLL), a disease characterized by the relentless accumulation of mature B cells has been little explored. Bone marrow stromal cells provide a survival benefit to CLL cells, in part through PI3K/AKT pathway. Compared with proliferative B-cell lines, …

    uthsc Repository record

  9. Analysis of Periodic and Random Capacitively-Loaded Loop (CLL) Metamaterial Structures for Antenna Enhancement Applications

    Hodge II, John AdamsVirginia Tech2014

    … a periodic array of capacitively-loaded loop (CLL) inclusions paired with continuous wire results in negative refraction, this study performs numerical simulations to characterize random metamaterial structures. These structures consist of CLLs that are randomized in both position and …

    vt Repository record

  10. Characterization of aberrantly spliced hsNotch1 variants induced by non-coding mutations in chronic lymphocytic leukaemia (CLL)

    Guo, MinUniversität Ulm

    ulm-diss Repository record

  11. NOTCH1 3’UTR Mutationen in der CLL: Inzidenz in jüngeren Patienten und Auswirkung auf die NOTCH1 mRNA

    Pittrof, AnselmUniversität Ulm

    ulm-diss Repository record

  12. Correlazione tra dati biologici e prognosi in pazieti affetti da B-CLL in stadio A secondo Binet

    GORGONE, AUSILIA GIUSEPPAUniversità degli studi di Catania2011

    … e dell'overall survival nei pazienti affetti da CLL in stadio iniziale. La maggioranza di questi markers prognostici ,anche se ormai in uso quotidiano nella pratica clinica, non è ancora incluso nelle linee guida internazionali che si basano ancora su criteri esclusivamente clinici e individuano …

    catania Repository record

  13. Stellenwert von IGHV-Mutationsstatus, CD38-Expression und chromosomalen Aberrationen innerhalb der CLL4-Studie der Deutschen CLL-Studiengruppe (DCLLSG)

    Binder, BirgitUniversität Ulm

    ulm-diss Repository record

  14. Untersuchungen zur Signaltransduktion des CXCR4 (CD 184) Chemokinrezeptors im Hinblick auf Vitalität und Migration humaner B-CLL-Zellen

    Rawluk, Justyna

    Die Chronische Lymphatische Leukämie (B-CLL) ist eine lymphoproliferative Erkrankung, bei der es charakteristischerweise zu einer Akkumulation von langlebigen CD5+, CD19+, CD23+ B-Lymphozyten im Blut, im sekundären lymphatischen Gewebe und im Knochenmark kommt. Akzessorische Zellen im Knochenmark …

    freiburg-diss Repository record

  15. Functional role of ZAP70 in Chronic Lymphocytic Leukaemia

    Sathiaseelan, VijithaUniversity of Cambridge2020

    Chronic lymphocytic leukaemia (CLL) is the most common type of leukaemia. It is common in older people and rare in people under 40. CLL is characterised by the accumulation of monoclonal CD5+CD23+ B lymphocytes in the blood, bone marrow and secondary lymphatic tissues. There are 2 main subtypes of …

    cambridge Repository record

  16. Targeting The Redox System to Overcome Mechanisms of Drug Resistance In Chronic Lymphocytic Leukemia

    Ogasawara, Marcia A2014

    <p>Chronic Lymphocytic Leukemia (CLL) is the most common form of leukemia diagnosed in Western countries and is characterized by clonal expansion of B cells. The clinical course of CLL is diverse and nearly 50% of patients present with chromosomal abnormalities. Deletion of the short arm on …

    uthsc Repository record

  17. CD200: A Novel Therapeutic Target for Chronic Lymphocytic Leukemia

    Wong, Karrie2013

    … blockade of CD200 on lymphoma cells or primary CLL cells, both of which express CD200 at high levels, augmented cytotoxic killing of these cells by effector CD8+ T cells in vitro. We also identified and characterized a previously unrecognized soluble form of CD200, sCD200, present in elevated …

    toronto-retro Repository record

  18. Functional interaction between CD180 Toll-like receptor (TLR) and B cell receptor (BCR) in the biology of Chronic Lymphocytic Leukaemia (CLL)

    Rajakaruna, A.University of Westminster2017

    Chronic Lymphocytic Leukaemia (CLL) is the most common leukaemia in the western world and remains incurable. It is driven by as yet unknown (auto)antigens via the B cell receptor (BCR) and growth, survival and expansion signals it receives from the microenvironment through a range of cytokines and …

    westminster Repository record

  19. CD180/RP105 Toll-like Receptor (TLR) mediated signalling in Chronic Lymphocytic Leukaemia

    Vispute, K.University of Westminster2013

    … progression of chronic lymphocytic leukaemia (CLL) is currently of major interest. Pathogen- and damage-associated molecular patterns (PAMPs and DAMPs, respectively) represent exogenous and endogenous microenvironmental factors acting via a range of receptors, including Toll-like receptors …

    westminster Repository record

  20. Understanding the biology of CD180 in chronic lymphocytic leukemia

    Edwards, K.University of Westminster2024

    … expressed on chronic lymphocytic leukaemia (CLL) cells from different patients. The loss of CD180 in CLL indicates that the receptor somehow confers a survival advantage for the tumour. In support of this, we found that CD180 expression was enriched in CLL cases with mutated immunoglobulin …

    westminster Repository record

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