Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"CD2AP"”.
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Dissection of CD2AP functions in epithelial cells
… for a molecular scaffolding protein known as CD2AP in controlling the height of the lateral membrane and the area of the apical and basal membrane domains. Depleting CD2AP resulted in a dramatic shortening of the lateral membrane but an expansion of the apical and basal membranes such that the …
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Nephrin und CD2AP aktivieren den PI3-Kinase/AKT-Signalweg im Podozyten
… glomerulären Schlitzmembranproteine Nephrin und CD2AP mit p85, der regulatorischen Untereinheit der PI3-Kinase, interagieren. <br>Die Interaktion von Nephrin und p85 ist Phospho-Tyrosin-abhängig und kann durch Genistein, das die Phosphorylierung des intrazellulären Nephrin-Abschnittes hemmt, …
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Elucidating the biological function of the uncharacterised protein FAM83G/PAWS1: Role in Wnt signalling through its interaction with Caseine Kinase 1α
… its dynamic interaction with the adapter protein CD2AP at the cell periphery. Here, PAWS1 has been shown to be phosphorylated at Ser356 by CaMK2D in cells and this phosphorylation event is demonstrated to be important for PAWS1-dependent cell migration.<br/><br/>Lastly, several PAWS1 mutations …
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Identification of Functional Variants in Alzheimer's Disease-Associated Genes
… uncovered common variants in ABCA7, BIN1, CD33, CD2AP, CLU, CR1, EPHA1, MS4A4A, and PICALM that contribute to AD; however, the most-significant variants in these loci are located within non-coding regions and have no direct functional impact on AD pathogenesis. We hypothesized that if PLD3 and …