Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"CD13"”.
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Platinum-NGR A Peptide Targeting Conjugate Of Cisplatin: Design, Synthesis, And Efficacy In Breast Cancer Cells
… interaction with aminopeptidase N (APN), or CD13, receptors. Fmoc solid phase chemistry was employed via a peptide synthesizer to produce mPeg-CNGRC-mal free peptide that was then cyclized and conjugated to activated cisplatin, producing a conjugated platinum-peptide complex specific to APN …
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Differenzierungsabhängige Modulation der Zytokin- und Chemokinexpression bei humanen myeloischen Zell-Linien
… der Oberflächenmoleküle (CD7, CD11b, CD11c, CD13, CD14, CD15, CD18, CD19, CD33, CD34, CD38, CD40, CD41, CD42b, CD45, CD45RA, CD45RO, CD61, CD69, CD71, CD95, CD154, Glykophorin A, HLA-DR), der Zytochemie (Myeloperoxidase, Lysozym, unspezifische Esterase) und der Zellmorphologie untersucht. Es …
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Peptide Targeting of Platinum Anti-Cancer Drug and Synthesis of Water Soluble Monofunctional Pt(II) Complexes Useful for Biological Labeling
… and destruction of cancer cells that had CD13 receptors compared to untargeted carboplatin drug. The development of targeted chemotherapeutic has opened a new approach for efficient delivery of antitumor toxins with minimal exposure to normal cells. Several peptide sequences are known to …
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Stellenwert der Immunzytologie in der Diagnostik und Verlaufsbeurteilung Akuter Myeloischer Leukämien (AML) : eine retrospektive Analyse aus der Medizinischen Universitätsklinik Freiburg 1994 - 1998
… <br>Patienten bei denen die Zellmarker MPO, CD13, CD33, CD65w und CD117 alle positiv waren, wiesen im Trend eine bessere Prognose auf als die übrigen Fälle. <br>Patienten, bei denen keine IPT durchgeführt wurde (n=24), wiesen signifikant häufiger eine sekundäre Genese und trendmäßig öfter ein …
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The significance of aberrant phenotypes and multidrug resistance for evaluation of the dynamics of minimal residual disease in acute leukemia patients /
… of patients with acute myelogenous leukemia (CD13+CD33+CD56+, CD5+, CD7+) are related to an increased multidrug resistance and through this mechanism influence a higher level of minimal residual disease. Aberrant phenotypes of patients with acute lymphoblastic leukemia did not correlate with …
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Etablierung einer Zellkultur von PDL-Fibroblasten aus parodontal erkranktem Zahnhalteapparat des Menschen
… Eine unveränderte Expression stellt sich für CD13 und CD73 als Faktoren, welche die Immunantwort modulieren, und für CD44 und CD29 als Adhäsionsmoleküle dar. Die statistische Auswertung der FACS-Ergebnisse ergibt, dass zwischen gesunden und parodontal erkrankten PDL-Zellen für Kollagen Typ I …
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Multilineäre Beteiligung der Leukämogenese in der BCR::ABL1-like Akuten Lymphoblastischen Leukämie
… konnte exemplarisch in CD33/CD13-positiven myeloischen Kompartimenten mit einer Frequenz von 56 % nachgewiesen werden. Weiterhin zeigte eine Probe eine Beteiligung myeloischer Kompartimente mit 11 % bzw. 10 %. Zusätzlich erfolgte der Translokationsnachweis mit 17 % in Stamm- …
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Adult Neural Stem Cells and Their Perivascular Niche
… purified from both the cortex and SVZ using CD13, CD146, and CD105. Interestingly, CD13+CD105-CD146- pericytes were the most proliferative population from both the SVZ and cortex, but only those from SVZ could be passaged. Staining with these markers in vivo demonstrated specific morphologies …
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Caracterização de células-tronco mesenquimais de camundongos normais e do modelo murino de MPS I
… CD29, CD44 e CD49e, e eram negativas para CD11b, CD13, CD18, CD19, CD31, CD45, CD49d e Gr-1 Este perfil de moléculas de superfície assemelha-se àquele descrito para a MSC humana, e indica ausência de contaminantes hematopoiéticos. Uma verificação preliminar da freqüência da MSC na medula óssea de …
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Sergančiųjų ūmine leukemija aberantinių fenotipų ir dauginio atsparumo vaistams nustatymas ir svarba vertinant minimalios liekamosios ligos dinamiką /
… of patients with acute myelogenous leukemia (CD13+CD33+CD56+, CD5+, CD7+) are related to an increased multidrug resistance and through this mechanism influence a higher level of minimal residual disease. Aberrant phenotypes of patients with acute lymphoblastic leukemia did not correlate with …
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Development of methods for the tissue engineering of cardiac valves using mesenchymal stem cells
… of hMSC indicated that the cells were CD45-,, CD13 +, D7FIB +/-, CD 105 +, CD 10 +/-, LNGFR +/-, CD55 + , BNP- and AP+/-. Analysis of hydroxyproline, sulphated proteoglycan and DNA content of the decellularised porcine valve tissue indicated no change in collagen or GAG content and removal of …
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pH Regulatory Molecules In The Tumour Microenvironment: Modulators Of Aggressiveness And Immune Profile Of Human Hepatocellular Carcinoma
… for HCC stem cell-associated markers (<i>CD13, CD24, CD44, CD90, EpCAM, CD133, KRT19, OCT4, NANOG</i> and <i>SOX2</i>). Selected HCC, non-tumour and normal liver tissue samples were evaluated by immunohistochemistry (IHC) to detect the presence and localization of CAIX, CAXII and VATPase …
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A single-site resolution fermionic quantum-gas microscope
Quantum-gas microscopes have become an important tool in quantum simulation as they enable direct probing of local quantities by single-atom-resolved detection in optical lattices. Recent years have seen many fascinating results from the bosonic quantum-gas microscopes using 87Rb. However, no such …
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Isosurface Interactions Within Turbulent Premixed Hydrogen and Hydrocarbon Flames
The purpose of this thesis is to provide better insight into isosurface interactions in premixed turbulent flames. These interactions for a suitable isosuface corresponding to the reaction zone can be interpreted as flame-flame interactions. Isosurface interactions can be identified with the help …
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Mapping the Feeding Circuitry in the Mouse and Human Brain
The prevalence of obesity and its associated comorbidities has significantly grown over the last 50 years, imposing a great burden on people’s health. Consequently, understanding the mechanisms by which energy intake and bodyweight are controlled is extremely important to help us to further improve …