Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 874 for “"CAS"”.
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Roles of non-Cas nucleases in Type III-A CRISPR-Cas immunity
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2025-08-01
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Le Rorschach dans les cas-limites
Etude à partir de 25 cas
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L'utilisation de cas concrets en pédagogie. Modèles pour décrire et analyser des cas et leurs usages didactiques
Dans l’enseignement supérieur, les « cas concrets » sont utilisés par bien des enseignants, de manière plus ou moins formalisée. Beaucoup y voient une façon de favoriser le transfert de la matière vue vers son utilisation en milieu professionnel. Mais ces cas concrets peuvent revêtir diverses …
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Differential polarization of Hβ in γ CAS
… across the Hβ emission line of the Be star γ Cas is presented. The differential polarization and polarization angle vary both in profile and depth. It was found that the polarization profile fits the relation PL, = (Iunderlying / Itotal)Pc, instead of the generally accepted PL = PC / …
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Cas protein diagnostics for pathogen nucleic acids
Cas protein diagnostics for pathogen nucleic acids - Akashaditya Das I formulated my research goals for my PhD in tandem with a Global Challenges Research Grant awarded to the Ajioka Lab in collaboration with other labs in the United Kingdom and South Africa. The grant aimed to develop tests for …
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Quantitative modelling of CRISPR-Cas editing outcomes
Development of the CRISPR-Cas toolkit over the last decade has enabled unprecedented control over the genome and unlocked the capacity for new experiments and gene-therapies. However, use of these technologies is made more difficult due to variance in the rate and type of individual genetic …
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Anti-CRISPRs and CRISPR-Cas: Characterization and Biotechnology
… systems, and the more recently discovered CRISPR-Cas immune systems. Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) loci together with their accompanying CRISPR-associated (Cas) genes form the only known bacterial adaptive defense mechanism that effectively protects against the …
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Trastorn de l'Espectre de l'Autisme: estudi de cas
L’objectiu d’aquest treball és descriure el cas del Marc, un noi d’11 anys que presenta un Trastorn de l’Espectre de l’Autisme (TEA) de grau 1 i el seu funcionament intel·lectual és superior a la mitjana poblacional. El TEA és considerat pel DSM-5-TR (APA, 2022) un trastorn del neurodesenvolupament …
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Nouveau système cimentaire cas de la Fritte de verre
Canada ranks as the world's third largest aluminium producer, and more than 80% of its aluminum industry is concentrated in Quebec. However, the spent pot-liner waste produced by the aluminium smelters accumulates with time into a considerable amount threatening the Canadian environment, especially …
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WEB Cas Pràctic boo-k : Gestió d'una Botiga Virtual
L'objectiu d'aquest treball és especificar, dissenyar i implementar una aplicació web que permeti l'operativa real dels serveis de gestió d'una botiga virtual d'Internet, amb el suport d'un sistema de gestió de bases de dades.
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Bacterial defense islands: CRISPR-Cas and toxin-antitoxin systems /
… enzymes, bacterial argonautes and CRISPR-Cas systems. CRISPR-Cas systems are located in the genome part called “defense islands” where genes encoding different antiviral systems are clustered together. The goal of this thesis is to explore the mechanisms of action of type I CRISPR-Cas and …
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A eukaryotic platform for the enhancement of Cas nucleases
A large repertoire of CRISPR-Cas systems from bacteria, archaea and phages is available for a large variety of genome editing applications. Nevertheless, a limited number of orthologs have the same editing efficiency as SpCas9 in mammalian cells. Moreover, Cas with reduced molecular size that have …
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Identification and Characterization of Novel CRISPR-Cas Immune Effectors
… bacteria have evolved to combat this are CRISPR-Cas systems, which have been studied extensively due to their fascinating biology and usefulness in biotechnology and therapeutics. My thesis focuses on the discovery and characterization of three new CRISPR-Cas effector proteins that provide …
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Cas9-Primed Adaptive Immunity During the CRISPR-Cas Response
… two components: a set of CRISPR-associated (cas) genes and a series of repetitive DNA elements intercalated with variable sequences known as spacers. Following viral infection, these sequences are acquired from the viral genome and integrated in the CRISPR array as new spacers. Spacers are …
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La radio en Afrique : Le cas du Burundi (2015).
… En lo que respecta a las iniciativas radiofónicas, los fundadores de las emisoras en África nos encontramos todo tipo de promotores, desde la Administración, las asociaciones, las iglesias y organizaciones religiosas, colectivos de mujeres, jóvenes, así como grupos de comunicación. Por otra …
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An integrated CRISPR-Cas toolkit for engineering human cells
… Short Palindromic Repeats (CRISPR)-associated (Cas) system is a prokaryotic adaptive immune system that confers resistance to foreign genetic elements including plasmids and phages. Very recently, a two-component CRISPR-Cas technology from Streptococcus Pyogenes comprising of the RNA-guided DNA …
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