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Showing 1 to 20 of 73 for “"Bone tissue engineering"”.
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Advances in Bone Tissue Engineering
Bone deficiencies, caused by malformations, trauma or adverse effects from medical treatments, are a clinical challenge and often associated with reduced physical function and quality of life. Autologeous bone grafts can be used to reconstruct skeletal defects, but the right size and quality of …
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Bioactive electrospun scaffoldo for bone tissue engineering
Contains fulltext : 105819.pdf (Publisher’s version ) (Open Access)
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Smart Materials for Cartilage and Bone Tissue Engineering
… and might progressively extend to subchondral bone, leading to the abnormal joint function and disability. Due to the avascular and condensed structure of cartilage, and the limited number of progenitor cells, it is challenging for regeneration of cartilage defects. Furthermore, because of the …
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Non-invasive shock wave stimulated periosteum for bone tissue engineering
… limited suitability for clinical applications of bone tissue engineering due to their low cell number (2-5 cells thick). Extracorporeal shock waves (ESWs) have been reported to cause thickening of the cambium layer and subsequent periosteal osteogenesis. This work proposes that ESW-therapy can be …
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TOWARDS PERSONALIZED BONE TISSUE ENGINEERING: CLINICALLY INSPIRED APPLICATION OF 3D BIOPRINTING
Tissue Engineering and Regenerative Medicine fields of life science and engineering strive to address medical challenges to human flourishing. Innovative research has led to many advances in the past two centuries with regards to treatment of orthopaedic trauma, but better options for treatment of …
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Fabrication and evaluation of inorganic-organic composites for bone tissue engineering /
… medical fields, especially in the field of bone tissue engineering. These activities are important for bioactive, bioresorbable and intelligent biomaterials that can substantially activate, promote and support biological processes that ensure tissue regeneration. There is a particular need …
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Development of a nanoHydroxyapatite-collagen composite scaffold for bone tissue engineering
Scaffolds for tissue engineering must meet certain requirements to make it suitable for use as a bone graft substitute, including a three-dimensional and highly porous structure, with an interconnected pore network to facilitate cell growth and transport of nutrients and metabolic waste products. …
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A multiscale mechanobiological investigation of scaffold designs for bone tissue engineering
Bone fractures and loss of bone caused by tumors and infections often require surgical intervention and reconstruction to ensure proper healing. Autografts, bone grafts taken from elsewhere in the patient's skeleton, are considered the gold standard for treatment; however, autografts are limited in …
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Stress Conditioning and Heat Shock Protein Manipulation for Bone Tissue Engineering
External stresses surrounding bone can stimulate heat shock proteins (HSPs), which are involved in anti-apoptosis, cell proliferation, and differentiation. In vitro stress modulation and HSP induction may be critical factors for enhancing bone regeneration. We investigated whether applying …
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Ovalbumin-Based Scaffolds Reinforced with Cellulose Nanocrystals for Bone Tissue Engineering
In the field of tissue engineering, a major area of study is developing bone scaffolds that will provide support for osteoblasts. Despite many advances in recent years there is still a significant need for new bio-based 3-D porous scaffolds that possess sufficient initial mechanical properties to …
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DEVELOPMENT OF SYNTHETIC POLYMERS FOR BONE TISSUE ENGINEERING: ENGINEERING THE DEGRADATION RATE
… cis (maleate) functionality into the polymer backbone, however a controlled fumarate to maleate ratio was only obtained via the acid chloride starting monomers. The PBF polymer differs from the previously examined PPF polymer through an additional methylene (CH2) unit in the polymer backbone. This …
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Bone Tissue Engineering: structures and strategies for functional scaffold design and evaluation
Skeletal tissue has a good ability to self-regenerate after injury through the processes of bone healing. However, bone can suffer from a wide range of pathologies, cancers or congenital defects which lead to loss of bone mass and density. Current progresses in tissue engineering have shown great …
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Freeze casting of bioactive glass and ceramic scaffolds for bone tissue engineering
… in the dorsum of rats showed abundant tissue ingrowth into the pores of the columnar scaffolds and integration of the scaffolds with surrounding tissue. The results indicate that bioactive 13-93 glass scaffolds with the columnar microstructure could be used for the repair of segmental …
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The Use of Dynamic Fluid Flow Strategies for Bone Tissue Engineering Applications
Bone is the second most transplanted tissue in the body, with approximately 2.2 million bone graft procedures performed annually worldwide. Currently, autogenous bone is the gold standard for bone grafting due to its ability to achieve functional healing; however, it is limited in supply and …
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Additive manufactured biodegradable and biocompatible polymeric nanocomposite scaffolds for bone tissue engineering applications
… functional biodegradable nanocomposite Polymeric Bone Tissue Scaffolds (PBTS). PBTSs are complex products, which have attracted significant attention in the literature in recent decades. In this study, a commercial and user-friendly FDM manufacturing technique was used to fabricate …
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Evaluation of Non-functionalized Single Walled Carbon Nanotubes Composites for Bone Tissue Engineering
<p>Introduction: Bone defects and non-unions caused by trauma, tumor resection, pathological degeneration, or congenital deformity pose a great challenge in the field of orthopedics. Traditionally, these defects have been repaired by using autografts and allografts. Autografts have set the gold …
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Modulation of the osteoblastic differentiation of marrow stromal cells for bone tissue engineering
The clinical need for bone graft substitutes has led tissue engineering strategies to investigate strategies to create osteoconductive, osteoinductive, and osteogenic constructs for bone repair and regeneration. The strategy in this research work is to use a cell-secreted extracellular matrix (ECM) …
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Multifunctional Nanocoatings Based On Biomimetic Collagen Type I For Bone Tissue Engineering Applications
Collagen heparin, layer-by-layer, scaffold, bone
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FABRICATION AND CHARACTERIZATION OF PHOTO-CROSS-LINKABLE NANOCOMPOSITE SCAFFOLDS FOR BONE TISSUE ENGINEERING
The large-scale bone defect is one of the biggest challenges in orthopedic surgery. Here, we proposed to use the photocrosslinkable nanocomposites for the fabrication of the bone scaffold and artificial periosteum. Firstly, we prepared nanocomposite ink composed of tri-block polymer and …
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