Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 105 for “"Biliary"”.
-
TRANSLATIONAL RESEARCH TARGETING BILIARY TRACT CANCER
<p>Biliary tract cancer (BTC) is malignant tumor that originates from the biliary tract, including cholangiocarcinoma (CCA) and gallbladder cancer (GBC). In this translational research program targeting BTC, we focus on three aspects: the development of a combination treatment against CCA, the …
-
Malignant Neoplasia of the Extrahepatic Biliary Tract
University of Minnesota Masters thesis. April 1922. Major: Surgery. 1 computer file (PDF); 64 pages.
-
Natural History of Biliary Sludge in Dogs
Background: Biliary sludge is associated with gallbladder (GB) dysmotility and mucus hypersecretion suggesting that these factors could lead to GB mucoceles. If biliary sludge does progress to GB mucoceles, treatments to reduce the production and progression of sludge are warranted. Objectives: The …
-
A THREE DIMENSIONAL MODEL OF HUMAN HEPATO-BILIARY ORGANOGENESIS
… formed bile duct structures by undergoing biliary morphogenesis process and attained apicobasal polarity in the organoids. The duct morphogenesis process was interrupted by inhibiting Notch signaling, thus creating a liver developmental disease model exhibiting a phenotype similar to …
-
Mechanisms of methylenedianiline toxicity to rat biliary epithelial cells
… polyurethanes and epoxy resins, rapidly injures biliary epithelial cells (BEC) of rats in vivo. DAPM also increases biliary inorganic phosphate and glucose, suggesting that DAPM loosens hepatic tight junctions. Early ultrastructural alterations in BEC mitochondria, however, suggested a possible …
-
Primary biliary cholangitis: genetic risk, phenotypic stratification and disease pathogenesis
Primary biliary cholangitis (PBC) is a rare disease which occurs in fewer than 1 in 2,000 people, mainly women over the age of 40. It is an autoimmune condition and is phenotypically associated with other immune-mediated inflammatory disorders (IMIDs). It is characterised by progressive destruction …
-
The differentiation of extrahepatic biliary atresia from the neonatal hepatitis syndrome
… an infant with cholestasis, between extrahepatic biliary atresia (EHBA) and the neonatal hepatitis syndrome (NHS) is important in that laparotomy is always indicated in EHBA but is undesirable in NHS. This differentiation is particularly difficult in those infants with complete cholestasis. …
-
ROLE OF NATURAL KILLER CELLS IN THE PATHOGENESIS OF PRIMARY BILIARY CHOLANGITIS
Background: Primary biliary cholangitis (PBC) is the most prevalent autoimmune liver disease and involves the selective destruction of small intrahepatic biliary epithelial cells (BECs), potentially leading to biliary cirrhosis and liver transplantation, if left untreated. As of now, …
-
Biliary atresia at Red Cross War Memorial Children's Hospital: A retrospective descriptive study reviewing the age of presentation, clinical course and outcome of infants presenting to RCWMCH with biliary atresia
Background: Biliary atresia (BA) is a progressive obstructive cholangiopathy of unknown aetiology, occurring during the perinatal period. If left untreated it rapidly progresses to hepatic fibrosis and cirrhosis, with death occurring within 2 years. It is the leading cause of end-stage liver …
-
Finite Element Analysis of a Novel Design for a Non-Migrating Biliary Stent
Biliary stenting is most frequently caused by an interruption in the ability to drain bile into the duodenum. This obstructive jaundice is commonly a result of a stricture from a tumor located at the pancreas’s head, peri-ampulary area, bile duct, or gall bladder. Jaundice can also occur from …
-
Duct-to-Duct Biliary Reconstructions and Complications in 100 Living Donor Liver Transplantation
Background. The biliary complications in duct-to-duct biliary reconstruction of right or left lobe living-donor liver transplantation (LDLT) have been reported various in incidence up to 40 %. And that could result in serious morbidity or mortality to the recipient’s. We evaluated the risk factors …
-
Surgery for Benign Biliary Tract Disease : An Analysis of 310 Cases from Smaller Hospitals
… Included]</p> <p>Summary:</p> <p>The results of biliary tract surgery in three small general hospitals serving suburban communities was studied. Their average daily censuses were 38, 70, and 97. Fourteen (4.5%) of 310 cases of benign biliary tract disease died after surgery. Among 219 cases of …
-
Resection of biliary mucinous cystic neoplasms: Study of a single institutional cohort and a literature review
Background: Biliary mucinous cystic neoplasms (BMCNs) are uncommon neoplastic septated intrahepatic cysts which are often incorrectly diagnosed and have the potential for malignant transformation. Aim: The aim of this study was to assess the outcome of surgical resection of BMCNs. Methods: Data …
-
Orthotopic liver transplantation at Groote Schuur Hospital : a serial analysis of biliary cytokines and biochemical parameters
… due to rejection from that due to infection, biliary obstruction or ischaemic injury without performing invasive procedures such as a liver biopsy or angiography which may be Clinically, the diagnosis of rejection is usually once the immunological process is already hazardous. made late, …
-
Characterization and therapeutic alteration of the biliary excretion and enterohepatic cycling of zearalenone in sexually immature swine
… of these studies were to characterize the biliary excretion and enterohepatic cycling (EHC) of zearlenone (ZEN) in young pigs and to therapeutically mimic the effect of bile removal in enhancing body clearance of ZEN. ($\sp3$H) ZEN was administered intravenously (IV), orally, and …
-
Snail1-mediated Gene Repression Links EMT to Enhanced Biliary Epithelial Cell Survival and Lung Epithelial Cancer Cell Migration
… to establish EMT in non-malignant murine biliary epithelial cells (cholangiocytes, 603B cells) and human lung epithelial carcinoma cells (A495 cells). We examined collagen production and cell survival in 603B cells and cell migration in A549 cells during TGF-β1-induced EMT. The involvement …
-
Understanding regional diversity in the human biliary tree through transcriptomic profiling of primary tissues and in vitro derived organoids
The biliary tree is a series of ductular tissues responsible for the drainage of bile produced by the liver and pancreatic secretions from the pancreas. The biliary tree is affected by a diversity of life- threatening diseases collectively called cholangiopathies. Cholangiopathies show …
-
An investigation of the Ciliary Protein PKHD1 in Cyst development in liver disease: clues to the pathogenesis of Biliary Atresia
Biliary atresia is a common form of paediatric liver disease, with progressive, inflammatory obliteration of the biliary tree, leading to liver failure early in life. Mutations in PKHD1, encoding the ciliary protein fibrocystin, are associated with autosomal recessive polycystic kidney disease …
Page 1 of 6