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Showing 1 to 20 of 102 for “"Bak"”.
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Leikið við ferðafólk : upplifun á bak við tjöldin
… leiklistar. Í rannsókninni er gerð grein fyrir bakgrunni þekkingar, fjallað er um menningartengda ferðaþjónustu, menningararf, þjóðsögur og ferðamenn, sviðslist, miðlunarleiðir, leikhúsform og leikhús fyrir ferðamenn. Notast var við eigindlegar rannsóknaraðferðir, nánar tiltekið þátttökuathugun, …
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Regulation of BAX/BAK-Dependent Cell Death Program
… apoptosis. Multidomain proapoptotic BAX/BAK promotes mitochondrial outer membrane permeabilization, whereas anti-apoptotic BCL-2/BCL-X<sub>L</sub>/MCL-1 protects mitochondrial integrity and prevents cytochrome c release. The proapoptotic activity of BAX/BAK is triggered by BH3-only …
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Mechanisms of BAK Activation in the Initiation of Mitochondrial Apoptosis
… targets. BCL-2 homologous antagonist/killer (BAK) is an effector of outer mitochondrial membrane (OMM) pemeabilization or mitochondrial poration. Despite progress in understanding BAK-mediated mitochondrial poration, the underlying multi-step mechanism is not clearly defined. Here, we provide …
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The Role of Bax and Bak in Necrotic Cell Death
… stimulation. Here we determined that Bax and Bak, Bcl-2 family members that are master regulators of apoptosis, are also required for programmed necrosis induced by Calcium, ROS, and DNA alkylation. These results led us to hypothesize that Bax and Bak are required for MPTP opening. Indeed, …
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„Þetta er kannski alltaf svona á bak við eyrað“ : kynjajafnréttismenntun elstu barna í sex leikskólum
Í þessari ritgerð er gerð grein fyrir því hvernig staðið er að kynjajafnréttismenntun elstu barna í sex leikskólum og er markmið rannsóknarinnar að fá sýn á þá kynjajafnréttismenntun sem fer fram í daglegu starfi. Tvær meginspurningar voru hafðar að leiðarljósi í rannsókninni: 1. Hvernig er staðið …
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The Modeling and Analysis of the Apoptotic BAD/tBID/BAK Pathway as a Chemical Reaction Network
… clean disposal of afflicted cells. The BAD/tBID/BAK pathway is a portion of the apoptosis molecular pathway, albeit an important pathway since it is known to be deregulated and lead to pathological ailments such as cancer. Using chemical kinetics the BAD/tBID/BAK signaling pathway is modeled as a …
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Antimalarial activity of hypoxis colchicifolia, bak, mimusops caffra, E. Mey. ex A.DC and mimusops obtusifolia, lam from South Africa
… of Sapotaceae family) and Hypoxis colchicifolia, Bak are used by traditional healers in Zululand to manage malaria. In this study, the plants were separately extracted exhaustively with methanol, ethyl acetate, hexane and dichloromethane (DCM). The crude extracts were screened for antioxidant, …
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Resources for the investigation of the desiccation tolerance mechanisms of the roots of Xerophyta humilis (Bak) Dur and Schinz
Although roots play an integral role in the sensing and amelioration of environmenatl stresses, there are no reports that specifically detail their involvement in the desiccation tolerance mechanisms of resurrection plants. Very lttle is known about even the genral anatomy and physiology of the …
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Gæði slagorða íslenskra vörumerkja : hvaða slagorð íslenskra vörumerkja eru eftirminnilegust og skilur fólk meininguna á bak við slagorð íslenskra vörumerkja?
… að því hversu vel skilja neytendur meininguna á bak við slagorð íslenskra vörumerkja. Rannsóknin skilgreinist sem megindleg rannsóknaraðferð og rafræn spurningakönnun var lögð fyrir 1160 manna úrtak. Lagt var mat á 22 slagorð vörumerkja, frá 13 mismunandi mörkuðum. Fræðilegur grunnur …
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Exploring the Activation Landscape of Pro-Apoptotic BAK Through the Discovery of Human BH3-Only and Non-Native Peptide Binders
BAK is one of the two pro-apoptotic members that form part of the BCL-2 protein family. Previous work has shown that binding of certain BH3-only proteins such as truncated BID (tBID), BIM, and PUMA to pro-apoptotic BAK leads to mitochondrial outer membrane permeabilization (MOMP), release of …
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Characterization of membrane lipids and, Changes therein during desiccation and rehydration of the resurrection plant Xerophyta humilis (Bak) Dur and Schinz
… in the resurrection plant Xerophyta humilis (Bak) Dur and Schniz. This was done in order to ascertain their roles during acquisition of desiccation tolerance in X. humilis. The galactolipids and glycerophospholipids acyl chain compositions were determined by multiple reaction monitoring (MRM) …
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Rapid turnover of McL-1 couples translation to cell survival and apoptosis
… or overexpression of Bcl-2 family proteins Bak and Bax were activated concomitantly with detection of cell death following cycloheximide treatment. Moreover, inhibition of the proteasome abrogated Bak/Bax activation, indicating that the loss of short-lived protein(s) induces mitochondrial …
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Schnarchen unter Alkoholeinfluss - eine klinische experimentelle Studie
… mit 0,5 ‰- und 0,8 ‰-Blutalkoholkonzentration (BAK). Die Schnarchgeräusche wurden mit einem Raum- und Körpermikrophon aufgezeichnet und computerunterstützt nach Häufigkeit und Lautstärke (>55 dB(A), >70 dB(A)) analysiert. Bei primären Schnarchern (n=10), die bereits ohne Alkohol schnarchten, …
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Developments in the Mutant Prevention Concentration: A Novel Approach to Antimicrobial Susceptibility/Resistance Issues
… by blood in the medium. Benzalkonium chloride (BAK) is a cationic surface-acting agent that acts on bacterial cells by disrupting the intermolecular interaction of the lipid bilayer. To determine if the fluoroquinolones gatifloxacin (Gfx) and moxifloxacin (Mfx) are more active (lower MIC values) …
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Vesicular stomatitis virus induced apoptosis occurs by a mechanism involving the activation of pro-apoptotic Bcl-2 proteins Bak and Bid and the inactivation of anti-apoptotic Bcl-2 proteins Bcl-XL and Mcl-1
… the two major proapoptotic multidomain proteins Bak and Bax, Bak is more important for the induction of apoptosis by rWT virus. Additionally activation of proapoptotic BH3-only protein Bid through activation of caspase-8 also plays an important role. Finally, inactivation of both antiapoptotic …
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Characterization of the Xerophyta humilis desiccation induced-1 (Xhdsi-1voc) gene : a member of the Vicinal Oxygen Chelate (VOC) metalloenzyme superfamily upregulated in X. humilis (BAK) DUR and SCHINZ during desiccation
The resurrection plant, Xerophyta humilis is used as a model system to identify and characterise genes which play an important role in conferring desiccation tolerance in plants. In this study, the expression of a novel gene named desiccation induced-1 (dsi-1VOC) during desiccation in X. humilis …
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Varaafl fyrir nýjan meðferðarkjarna og rannsóknarhús við Hringbraut
… Hringbraut. Fjallað verður lauslega um fræðin á bak við verkefnið svo hægt sé að mynda sér skoðun og taka rökstudda ákvörðun um framhaldið.
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Samhengi milli skrokkmála og sköpulagsdóma hjá íslenskum kynbótahrossum
… við eiginleikana háls, herðar og bóga, bak og lend og samræmi var einnig skoðað. Helstu niðurstöður voru að hefðbundin skrokkmál og reiknuð skrokkmál höfðu marktæk áhrif á aðaleinkunn fyrir sköpulag. Þau mál voru: Hæð á herðar, Hæð á bak, Hæð á lend, Brjóstdýpt, Bollengd, Breidd um …
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Molecular Mechanisms of Programmed Necrotic Death Initiated by Intrinsic Death Signals
… mitochondrion apoptosis effectors BAX and BAK to execute death. Yet, combined loss of Bax and Bak causes developmental and homeostatic defects in restricted tissues, indicating the existence of additional death program(s). By using Bax-/-Bak-/- double- knockout (DKO) mouse embryonic …
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