Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Animal Structures"”.
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Differential Endometrial Responses of Primates vs Rodents: Screening for Antiproliferative Effects of Antiprogestins
<p>The antiprogestin, mifepristone, has previously been shown to noncompetitively inhibit estrogen-induced endometrial proliferation in nonhuman primates (van Uem et al., 1989; Wolf et al., 1989b; Neulen et al., 1990; Neulen et al., 1996). For both economical and ethical reasons, we are encouraged …
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Cellular Mechanisms Underlying Myogenic Reactivity in Isolated Arterioles
<p>The myogenic reactivity provides one of the principal mechanisms for blood flow autoregulation. The aims of the performed studies described in this dissertation were to test the role of [Ca<sup>2+</sup>]<sub>i</sub> and MLC phosphorylation in arteriolar myogenic reactivity and further examine …
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Interaction of ACTH and Estradiol in the Regulation of Growth, Differentiation, and Steroidogenic Maturation of the Baboon Fetal Adrenal Gland
… in size was maintained in betamethasone-treated animal. These data indicate that ACTH induces the differentiation of the transitional zone and thus the potential for the fetal adrenal to synthesize cortisol.</p> <p>To test the hypothesis that estrogen modulates the role of ACTH on fetal adrenal …
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Mouse Oocyte Maturation and Embryo Development After Exposure to Vemurafenib (PLX4032), an Anti-Melanoma B-RAF V600E Inhibitor
<p>Vemurafenib is a selective B-Raf<sup>V600E</sup> inhibitor in melanoma targeted therapy which also inhibits the wild type B- and C-Raf. In oocyte maturation, the C-Raf/MAPK pathway acts as an important self-enhancing and promoting system, w hereas in embryo development, the C-Raf/M APK pathway …
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Endothelial Nitric Oxide Synthase and Growth Factor Regulation of Flow-Mediated Vascular Remodeling
… second-order branch arteries compared to same animal control vessels. Neither mean carotid nor local mesenteric arterial pressures changed significantly pre- to post-ligation. The primary flow-mediated force in both vessels was shear stress with possible involvement of acute stretch-induced …
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The Ultrastructure of the Olfactory System in Two Species of Short-Tailed Shrews, <i>Blarina brevicauda</i> and <i>Blarina carolinensis</i>
… microscopy protocols. The olfactory system structures investigated included the olfactory epitheliumlmucosa (OEM), main olfactory bulb (MOB), accessory olfactory bulb (AOB), anterior olfactory nucleus (AON), olfactory tubercle (OT), and piriform cortex (PC). A new type of supporting cell, …
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Protein Utilization and Requirements in Broiler Breeders
<p>Advances in the genetics of poultry have created unintended consequences to the broiler breeder industry. Excessive weight has been shown to have many negative effects, including double hierarchies, multiple ovulations, and fatty liver. In an effort to curb excessive body weight gain, both the …
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Estrogen Regulation of the Pregnant Baboon Placental 11β-Hydroxysteroid Dehydrogenase (11β-HSD)-Catalyzed Metabolism of Cortisol and Cortisone and Its Effect on the Development of the Fetal Hypothalamic-Pituitary-Adrenal Axis
… and increased on day 100 in estrogen-treated animals. Immunohistochemical studies confirmed that ACTH protein paralleled changes in POMC mRNA. Next, we determined whether the ontogenetic increase in POMC/ACTH in fetal baboon pituitaries reflected an increase in hypothalamic …
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Investigation of Determinants of Agility Performance in Soccer
<p>Soccer players change direction repeatedly throughout a game, making agility an important component of their performance. The purpose of this project was to identify how anatomical and physical characteristics influence agility performance among soccer players. The influences of anthropometry, …
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Taurine's effect on cocaine reward and neurogenesis in the adolescent male rat brain.
<p>Adolescence is a developmentally critical transition from childhood to adulthood including both maturation of the body and the brain. Neuroplastic changes result in dynamic organization of the brain during adolescence, leaving them vulnerable to development of mental illness and drug-seeking …
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Investigating prefrontal cortex neuronal signatures of opioid-induced risk-taking behavior
<p>Opioid use disorder occurs alongside impaired risk-related decision-making, but the underlying neural correlates are unclear. We developed an approach-avoidance conflict task using a modified conditioned place preference procedure to study neural signals of risky opioid seeking in the prefrontal …