Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 48 for “"Amoeba"”.
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AMoEBA: the adaptive modeling by evolving blocks algorithm
<p>This dissertation presents AMoEBA, the Adaptive Modeling by Evolving Blocks Algorithm. AMoEBA is an evolutionary technique for automatic decomposition of data fields and solver/descriptor placement. By automatically decomposing a numerical data set, the algorithm is able to solve a variety of …
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Generation of cDNA libraries of amoeba, 8 hour, and 12 hour stages of Dictyostelium discoideum
… gp-2 expression, cDNA plasmid libraries of amoebae, and cells at 8 h and 12 h of development were generated. The long-term goals of this project involve screening expression libraries with identified cis-acting elements from the gp-2 promoter to yield the DNA binding proteins responsible for …
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Investigating the protein quality control pathways that prevent protein aggregation in the social amoeba Dictyostelium discoideum
… investigated molecular chaperones of the social amoeba, Dictyostelium discoideum, an organism resistant to polyglutamine (polyQ) protein aggregation and whose proteostasis pathways have not been intensively studied. Serine- rich chaperone protein 1 (SRCP1), a Dictyostelium-specific chaperone, was …
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Opportunistic Pathogens and the Brain-eating Amoeba, Naegleria fowleri in Reclaimed Water, Municipal Drinking Water, and Private Well Water
… OP, Naegleria fowleri (i.e. brain-eating amoeba). Three phases of investigation were carried out to identify factors that facilitate the growth of OPs in main distribution and premise plumbing systems, with particular attention on reclaimed water systems, aging water mains, and private …
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The missing dimension of cell membrane organization. Study on cubic membrane structure and function
… inner membranes of the free-living giant amoeba (Chaos carolinensis). In this organism, mitochondrial inner membranes undergo dramatic changes in 3D organization upon food depletion, providing a valuable model. As first step toward understanding the factors controlling cubic membrane …
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An adaptive partitioning scheme for ad-hoc and time-varying database analytics
… for such settings. In this thesis, we present Amoeba, an adaptive distributed storage system for data skipping. It does not require an upfront query workload and adapts the data partitioning according to the queries posed by users over time. We present the data structures, partitioning …
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Étude de systèmes d'exploitation en vue d'implanter un système à base de connaissances de répartition de charge
… d'exploitation. Ces systèmes sont Minix, Linux, Amoeba et Mach. Une description de ces quatre systèmes d'exploitation est réalisée avant l'application des dernières étapes de la méthode de comparaison. La dernière étape, qui consiste en la comparaison proprement dite, favorise le système Amoeba. …
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Characterization of cathepsin B cysteine protease from Naegleria fowleri excretory-secretory proteins exerting immunomodulatory effects
Naegleria fowleri, a free-living amoeba that is found in diverse environmental habitats, can cause an acute fulminating hemorrhagic meningoencephalitis, called primary amoebic meningoencephalitis (PAM) in experimental animals and in humans. Pathogenicity of N. fowleri may be induced by …
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Development of a High Temperature Gas-Cooled Reactor TRISO-coated particle fuel chemistry model
… of the SiC layer are additionally modeled. The amoeba effect is added as a new failure mode. The palladium penetration model has the most significant result on the overall fuel performance model and increases the number of predicted particle failures. The thinning of the SiC layer due to fission …
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Microbiology and cell biology of the interaction between Listeria monocytogenes and Acanthamoeba spp.
… be contact with other microorganisms, including amoebae, which naturally feed on bacteria as a source of nutrients. In this context, research has shown that several intra-cellular pathogens are able to survive or replicate within free-living amoebae. In view of the potential for amoebae to act as …
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Cytopathic Effects of a Pathogenic Naegleria fowleri and an Anti-Nfa1 Antibody on Rat Microglial Cells
Naegleria fowleri, a free-living amoeba, causes fatal primary amoebic meningoencephalitis (PAME) in experimental animals and humans. On the pathogenic mechanisms of N. fowleri concerned with host tissue invasion, the adherence of amoeba to host cells is most important. The nfa1 gene (360 bp) was …
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Experimental Studies on the Microbiota associated with Urinary Tract Infections
… issue relates to the ubiquitous protozoa, Acanthamoeba. Although it is known to cause infections in humans, the amoeba has been isolated from apparently healthy people. Furthermore, Acanthamoeba is known to have an endosymbiotic relationship with bacteria. Therefore, it is reasonable to …
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Modeling of Electrostatic Interactions inside Human Voltage-Gated Sodium Channels
… from molecular dynamics simulations using the AMOEBA force field serve as effective indicators for identifying residues crucial to protein function.
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Establishing an ex vivo model of acanthamoeba keratitis and investigating the phenotypic similarities between the protozoan acanthamoeba and human macrophages
Acanthamoeba is a small free-living amoeba found in tap water and soil with two life stages: the trophozoite and cyst. Acanthamoeba species are opportunistic pathogens of humans that cause two main diseases including a potentially blinding infection of the cornea called Acanthamoeba keratitis (AK) …
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The Effect of Coating Parameters On Advanced TRISO Fuels With Zirconium Carbide
… presence of a temperature gradient, known as the amoeba effect. To negate these problems a solution of adding a ZrC gettering layer between the kernel and PyC buffer layer has been proposed. The purpose of this study is to provide insight into the coating parameters and how they affect the coating …
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<i>Dictyostelium discoideum</i> Protein Kinase C-orthologue <i>pkcA</i> Regulates the Actin Cytoskeleton through Interaction with Phospholipase D and p21-activated Kinase
… morphology, and directed motility. The social amoeba, Dictyostelium discoideum, is used as a simple model system to study the translation of extracellular signals to the actin cytoskeleton. When starved, these unicellular amoebae undergo a multicellular developmental process characterized by a …
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Inflammasome activation in THP-1 target cells triggered by pathogenic Naegleria fowleri
Naegleria fowleri, also known as the brain-eating amoeba, causes acute primary amoebic meningoencephalitis. During swimming and other recreational water activities, N. fowleri trophozoites penetrate the nasal mucosa and invade the olfactory bulbs, resulting in intense inflammatory reactions in the …
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The Development of Actuators for the Whole Skin Locomotion Robot
… to the cytoplasmic streaming exhibited by an amoeba. In the robot there are embedded ring actuators which evert the material of the robot to produce forward motion. The robot benefits from a highly flexible exterior allowing it to squeeze into constricted passageways or collapsed structures. …
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Cell death and Pro-inflammatory Cytokine Release of Rat Microglial Cells by Naegleria fowleri
Naegleria fowleri, a free-living amoeba, causes fatal primary amoebic meningoencephalitis in humans and experimental animals. In previous study, N. fowleri trophozoites showed the highly cytopathic activity and cytotoxicity against rat microglial cells by the morphological observation and 51Cr …
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Comparison of accuracy and efficiency of five digital image classification algorithms
… a range of available techniques including: a) AMOEBA (an unsupervised clustering technique with a spatial constraint) b) ISODATA (a hybrid minimum distance classifier) c) BOXDEC (a discrete parallelepiped classifier) d) BCLAS (a Bayesian classifier) e) HYPBOX (a combined parallelepiped-Bayesian …
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