Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 152 for “"Action Potentials"”.
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Action potentials as indicators of metabolic perturbations for temporal proteomic analysis
… of predicting and identifying protein interactions. Several tools have been developed to explore how a compound interferes with specific pathways. However, these tools lack the potential to chronically monitor the time dependent temporal changes in complex biochemical networks, thus limiting …
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Optical measurement of neural action potentials using low coherence heterodyne interferometry
… optical method for detection of neural action potentials using low coherence interferometry. The dual beam heterodyne interferometer (DBHI) is a modified Michelson with a low coherence source and an optical referencing method capable of detecting sub-nanometer optical path changes. In …
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A Prototype Device for Isolating and Wirelessly Transmitting Neural Action Potentials
… of neurons in the hippocampus are manifested as action potentials or voltage "spikes" on the order of 100 to 400uV in magnitude. Though the information content of the neural signal is riding on these action potentials, the spikes comprise a small fraction of the complete neural signal. A unique …
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Conducting polymer hydrogels for the release of glutamate and sensing of extracellular action potentials
… population and often involve abnormal neuronal action potential firing and chemical signalling in the brain. Conventional treatment options including oral and systemic administration of drugs have limited ability to cross the blood brain barrier and hence require frequent administration of drugs …
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The initiation of action potentials and the passive electrical properties of identified snail neurones
… of neuronal membranes and the initiation of action potentials. The passive electrical properties of a neurone, together with its morphology, determine the efficiency of synaptic current transfer to the impulse initiation zone. A general analysis was made of the problems of estimating the …
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Excitable fibroblasts! : ion channels, gap junctions, action potentials and calcium oscillations in normal rat kidney fibroblasts
Contains fulltext : 19366.pdf (Publisher’s version ) (Open Access)
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Design of High-Resolution SAR ADC for Detection of Sub-Cortical Neuron Action Potentials for BMI Applications
… capable of resolving both fast, low-amplitude action potentials (APs) and slow, higher-amplitude local field potentials (LFPs) under stringent power and area constraints. This thesis presents the design and simulation of a high-resolution, low-power successive approximation register (SAR) …
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Medial olivocochlear efferent (MOC) effects on stimulus frequency otoacoustic emissions (SFOAEs) and auditory-nerve compound action potentials (CAP) in guinea pigs
In humans, SFOAEs can non-invasively assess MOC strength and, may predict the MOC reduction of damage from traumatic sounds. However, the functionally important MOC effect is inhibition of auditory-nerve (AN) responses. Understanding the relationship between MOC effects on SFOAEs and AN CAPs is …
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SOLVING THE CABLE EQUATION, A SECOND-ORDER TIME DEPENDENT PDE FOR NON-IDEAL CABLES WITH ACTION POTENTIALS IN THE MAMMALIAN BRAIN USING KSS METHODS
… the Cable Equation. The Cable Equation measures action potentials in axons in a mammalian brain treated as an ideal cable in the first part of the study. We shall subject this problem to the further assumption of a non-ideal cable. Assume a non-uniform cross section area along the longitudinal …
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Development and implementation of hardware and software for a minicomputer based programmable interval timer for use in point process analysis of neuronal action potentials
… use in point process analysis of the neutronal action potentials derived from multiple extracellular electrode arrays is described. The PIT is based on a commercially available LSI package, INS8253 and is interfaced to a Data General (DG) microNova 16-bit microcomputer via a DG General Purpose …
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Technologies for and Electrophysiological Studies of Structured, Living, Neuronal Networks on Microelectrode Arrays
… and found patterned neurons capable of firing action potentials. Their firing depended on neuronal communication as action potentials were suppressed by high magnesium media. In addition, we found that network activity depended on network morphology. Well-confined networks fired action …
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Intrinsic Neuronal Plasticity of Kiss1 Neurons in Mice around Puberty
… mice showed a significantly lower number of action potentials, and a higher firing frequency compared to Kiss1ARC neurons in 4-week and post-pubertal mice. In contrast, in male mice, Kiss1ARC neurons between 3w and 6-8w did not show many significant differences, suggesting that the plasticity …
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Time-varying phase relationship between spiking neuronal responses and local field potentials in olfactory processing in manduca sexta
… odor driven oscillations, the phase-locking of action potentials to LFP oscillations, and the role of GABAA receptors in the generation of these oscillations. We quantified the changes in LFP oscillation frequency over time via time-frequency representation (TFR) analysis, and calculated the …
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Characterization and application of human pluripotent stem cell-derived neurons to evaluate the risk of developmental neurotoxicity with antiepileptic drugs in vitro
… glutamate receptors. These cells could also fire action potentials when stimulated electronically. However spontaneous action potentials were not observed. In contrast, pre-differentiated neurons derived from iPS cells fired evoked and spontaneous action potentials. Furthermore, iPS cell-derived …
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Analysis and reduction of a modeled bursting neuron
… were significantly perturbed by the firing of action potentials. The results of the numerical analysis were applied to develop a reduced model of the underlying subthreshold oscillations (slow-wave) in membrane potential. Two different low-order models were developed: a 3-variable model, which …
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Perturbation Based Decomposition of sEMG Signals
… electromyography records the motor unit action potential signals in the vicinity of the electrode to reveal information on muscle activation. Decomposition of sEMG signals for characterization of constituent motor unit action potentials in terms of amplitude and firing times is useful for …
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EMG-based determination of upper extremity virtual trajectory
… of the human body are controlled by the interaction between the muscle and the peripheral and central nervous system. This interaction is nothing but the neural signals. Neural signals are electrical in nature and referred as action potentials. An EMG is a summation of action potentials from …
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Potenciais propagantes no músculo oblíquo interno por eletromiografia de superfície de alta densidade
… was proposed to estimate the direction of the action potentials of the motor units of the internal oblique muscle. The results showed that it was possible to identify propagating action potentials in the direction of the fibers in agreement with the architecture of the internal oblique muscle …
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Information Encoding by Individual Neurons and Groups of Neurons in the Primary Visual Cortex
… visual information is encoded into the times of action potentials in those responses (as opposed to the overall rate), and also into the identity of the neuron that fires each action potential (as opposed to the average activity across a group of nearby neurons). The data are examined with …
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Ion channels and electrical excitability in native murine anterior pituitary corticotrophs
… murine corticotrophs displayed spontaneous action potentials with highly heterogeneous firing patterns including single spikes and variable “pseudo plateau bursting” action potentials. The resting membrane potential of native murine corticotrophs was maintained by a TTXresistant background …
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