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Showing 1 to 20 of 102 for “"ALLELE FREQUENCIES"”.
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Using Dirichlet Process Priors For Bayesian Mixture Clustering
… that a population is characterized by a set of allele frequencies that follow multinomial distributions. The Dirichlet Process is applied as the prior distribution. The method estimates the number of populations together with the allele frequencies and the ancestry coefficients of each …
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The Association of Specific EPHX1 and GSTM1 Gene Polymorphisms with Phenytoin- or Smoking-Associated Birth Defects
… methods included polymerase chain reaction and allele-specific restriction enzyme digest on DNA samples of affected and non-affected individuals. Results: The allele frequencies at EPHX1 codon 113 in the phenytoin exposure population appeared to differ from the reported allele frequencies by …
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Electrophoretic, Morphometric, and Meristic Comparisons of Walleye Broodstock in South Dakota
… compared to the South Dakota stocks. Allele frequencies of two (MDH-3, GMP-3) of the twenty-one loci examined differed significantly (P<0. 05) between South Dakota and Mississippi River walleyes. Contingency chi-square tests of allele frequencies showed homogeneity among walleyes from …
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Population Genetic Structure of the Introduced North American Population of the Hornet, Vespa Crabro Germana Christ
… and European populations as did numbers of alleles per locus and allele frequencies. Perhaps the most compelling data from this investigation was that, for one locus, there was but a single allele found for all of North America. This confirmed the earlier conclusion from the mitochondrial …
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Population genetics of the genus Transennella (Bivalvia)
… oxidase, and nonenzymatic protein, Observed allele frequencies for these systems are in close agreement with Hardy-Weinberg expectations indicating that these protandric hermaphrodites are outbreeding. The genus is characterized by two distinct morphotypes which differ in shell shape and …
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Constructing a DNA profile frequency database for South Africa using the Qiagen Investigator 24plex GO! Kit
… matched to a known reference sample. The use of allele frequencies from the background population aids the statistical interpretation of a match and can be used to calculate the random match probability. In South Africa, allele frequency data for the background population is currently limited, …
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AN ELECTROPHORETIC ANALYSIS OF THE GENETIC VARIATION IN THE WILD AND CULTIVATED SOYBEAN GERMPLASM
… level), and a significantly higher number of alleles/locus (1.8 vs. 1.5). Nearly 50% of the shared alleles had significant differences in frequencies. While the overall correlation between allele frequencies was high (R = .84, for variable loci), this correlation was reduced (R = .23) when …
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Examination of HIV-1 diversity and evolution by a bioinformatics approach
… functional sites of the two proteins, calculated frequencies of HLA alleles targeting CTL epitopes, and compared PS patterns among major subtypes. The results showed that PS pressure was widely dispersed across the entire regions of both HIV-1 Env and Gag proteins, suggesting the conserved regions …
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Rare Variant Association Studies In Crohn’S Disease and Colorectal Cancer: Methods and Applications
… 4 described a new method to Leverage External Allele Frequencies (LEAF) in case-control studies to improve statistical power. LEAF detects and removes variants that are unlikely to substantially increase disease risk by comparing allele frequencies in the combined internal case-control dataset …
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Role of the RUNX2 rs59983488 variant in bone mass determination and fracture risk in Malta
… of this study was to determine the genotype and allele frequencies of the RUNX2 rs59983488 variant in the Maltese population, and to investigate the effect of the variant on reduced BMD and fracture risk at specific anatomical sites. Genotyping was performed using Competitive Allele-Specific PCR …
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A pilot study to identify links between genetic variation and shoulder pain and dysfunction after breast cancer radiotherapy
… There was a significant difference in the minor allele frequencies between case and control groups for the rs4880 (C>T, SOD2) polymorphism. The T allele was present more in the case group than in controls, with minor allele frequencies of 0.67 vs 0.55 respectively. No other independent …
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The characterization of MHC Class II genes of the Nile crocodile (Crocodylus niloticus) : an investigation of mechanisms that shape genetic diversity in natural populations
… of the Nile crocodile. Temporal variation in allele frequencies for MHC and microsatellite loci was assessed in four successive cohorts of crocodiles from the Okavango Delta, Botswana. Results from this study suggest that a combination of short-term neutral forces such as random genetic drift, …
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Diachonic DNA Analyses of Animal Breeds and Populations
… I found no evidence for change in coat colour allele frequencies. Conversely, in the biased and small historic Thoroughbred dataset, the mitochondrial genome was insufficient to provide population-level information, but I was able to show that allele frequencies in the nuclear MSTN gene, a gene …
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Landscape genetics and CWD in white-tailed deer
… prevent their negative impacts. We detected null alleles in five of 13 previously evaluated microsatellites, and redesigned primers for two of these loci. Analytical corrections for null alleles were unable to fully prevent bias associated with these genotyping errors, and consequently, measures …
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Molecular genetic mechanisms of eosinophil activation in aspirin-exacerbated respiratory disease : Genetic mechanisms of eosinophil activation
… differences in genotype, haplotype and allele frequencies of IL5 polymorphisms between the two groups. Asthmatics carrying the AG/GG genotype at –746A>G had a significantly higher prevalence of serum specific IgE to SEA (p=0.008), higher total IgE levels (p=0.014), and lower PC20 …
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Asymptotic Analysis of Some Stochastic Models from Population Dynamics and Population Genetics
… Moran’s continuous time Markov chain model of allele frequencies in haploid populations of fixed size with the density dependent models of ecological competition of Lotka, Volterra, Gause, and Kolmogorov. This allows for haploid populations of stochastically varying – but bounded – size. …
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Systematics of Eastern North American Bracken Fern
… patterns of geographic variation for isozyme allele frequencies were also observed. The isozyme results did not separate the two taxa. Numerical analysis of the morphology distinguished the two taxa when the qualitative characters were used alone or in conjunction with some of the quantitative …
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Genetics of age-related macular degeneration and Stargardt disease in South African populations
… SNPs within known AMD candidate genes in which allele frequencies were significantly different (i.e. 10 fold) between Caucasians and indigenous southern Africans. Nine SNPs occurring at higher frequencies within Africans compared to Caucasian controls were genotyped by SNaPshot PCR within a …
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The role of genetic factors and lifestyle relationship to obesity and metabolic syndrome in a sample of Bulgarian population // Проучване ролята на генетични фактори и начина на живот за изявата на затлъстяване и метаболитен синдром в извадка от българската популация
… parameters were studied and evaluated. The allele frequencies of four genes by selected single nucleotide polymorphisms were investigated in a sample of Bulgarian population and compared to the same polymorphisms in different populations. A demographic and social characteristics of the …
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Genetic differentiation of the parasitoid, Cotesia congregata (Say), based on host-plant complex
… and the mitochondrial COI locus. Microsatellite allele frequencies were differentiated based on host-plant complex, and COI haplotypes from individuals on the same host-plant were identical despite geographic distances between catalpa sites of up to 830 km and distances between tobacco sites of …
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