Systemic and Regional Distribution of Blood Flow During T-2 Toxin Induced Shock in Swine (Microspheres)

Three groups of swine (6 per group) were used to assess alterations in blood flow induced by single doses of T-2 toxin infused into the pulmonary artery. Two groups were dosed at 0.6 or 2.4 mg/kg T-2 toxin and the third group served as a vehicle control (70% ethanol). Organ blood flow was determined at 0 hour (predosing) and at 90 minute intervals for 6 hours, using the radiolabeled microsphere technique. Hemodynamic parameters were obtained at the same time points.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Veterinary Medical Science

Grantor

University of Illinois at Urbana-Champaign

Date dc:date

10000-01-01

Author dc:creator

• Lundeen, Gregg Richard

• Biology, Veterinary Science

Identifier

(UMI)AAI8711831

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/71343