The Determination of Glucuronides in Biological Fluids by Lucigenin Chemiluminescence (beta-Glucuronidase, Glucuronic Acid, Immobilized Enzyme, (Hplc))

The use of certain chemiluminescence reactions as detection techniques for organic compounds has been explored during the past decade. In this research project the chemiluminescence reaction between alkaline lucigenin (10,10'-dimethyl-9,9'-biacridinium nitrate) and glucuronic acid (an important organic reductant in humans) was studied. The main goal of this project was to develop an analytical method for the quantitation of conjugated glucuronic acid (i.e., glucuronides) in physiological fluids using this chemiluminescence reaction as the detection technique.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Chemistry

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2014

Author dc:creator

• Klopf, Lori Lynn

• Chemistry, Analytical

Identifier

(UMI)AAI8511628

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/70292