Abstract
dc:description.abstractNear infrared (NIR) lasers have been used in medical applications both for diagnostic and therapeutic purposes. Temperature elevation profile inside the tissue is a critical factor that needs to be better understood in these applications. The purpose of this study is to determine the temperature distribution due to a low power N I R laser irradiation in living neural tissue. Temperature measurements were made directly using a thermocouple probe inside the rat brain cortex within the sagittal plane. The spatial map indicates that N I R light penetrates more readily in the vertical directions than the spreading in the horizontal axis. The decrease in the vertical direction can be approximated with a single order exponentially decaying function. The results also suggest that the temperature elevation can be kept below 0.5 C anywhere in the tissue if the incident laser beam power density is less than 27 mW/cm^2. These experiments should be repeated in other types of neural tissue such as the white matter of the brain and the spinal cord to obtain more complete results.
Degree
thesis:*- Name thesis:degree_name
- Master of Science in Biomedical Engineering - (M.S.)
- Discipline thesis:degree_discipline
- Biomedical Engineering
- Year
- 2012
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Ersen, Ali
- Contributors dc:contributor
-
- Mesut Sahin
- Bryan J. Pfister
- Yahia M. Al-Smadi
Subjects
dc:subject × 4Identifiers
dc:identifier.*- Repository record dc:identifier
- https://digitalcommons.njit.edu/theses/114
- OAI identifier oai:identifier
- oai:digitalcommons.njit.edu:theses-1113