ΝΕΥΡΟΦΥΣΙΟΛΟΓΙΚΗ ΜΕΛΕΤΗ ΤΟΥ ΠΕΡΙΦΕΡΙΚΟΥ ΝΕΥΡΙΚΟΥ ΚΑΙ ΜΥΙΚΟΥ ΣΥΣΤΗΜΑΤΟΣ ΣΕ ΑΣΘΕΝΕΙΣ ΜΕ ΟΜΟΖΥΓΟ Β-ΘΑΛΑΣΣΑΙΜΙΑ

WE PERFORMED EMG STUDIES IN 53 PATIENTS, TREATED DURING THE PAST FIVE YEARS IN A UNIVERSITY THALASSEMIA UNIT AND IN 29 CONTROLS OF THE SAME AGE RANGE (5 TO 35YEARS). WE STUDIED SEPARATELY SEVEN THALASEMIC PATIENTS WITH THE COMPLICATION OF DIABETES MELLITUS. FROM THE DETAIL CLINICAL EXAMINATION (MEDICAL HISTORY ANDPHYSICAL EXAMINATION) IT WAS FOUND THAT 23% OF THE PATIENTS PRESENTED WITH SENSORY SYMPTOMS (NUMBNESS AND TINGLINGS) IN THE LOWER LIMBS, 17% WITH CRAMPS AND 15% WITH MUSCULAR PAINS. FURTHERMORE 13% OF THE PATIENTS HAD DIMINISHED KNEE JERK AND 19% THE ACHILLES TENDON REFLEX. IN 4% OF PATIENTS THE ACHILLES REFLEX WAS ABSENT. MOTOR CONDUCTION VELOCITIES (MCV) FOR THE DEEP PERONEAL AND THE TIBIAL NERVE WERE REDUCED IN THE PATIENT GROUP COMPARED WITH THE CONTROL GROUP (49.13.37 M/S, SE-0.46 AND 52.2 2.79 M/S, SE=0.51 T-TEST 4.49 FOR THE PERONEAL NERVE AND 48.7 4. 41 M/S, SE=0.56 AND 51.65 3.23 M/S, SE= 0.60 T-TEST 3.58 FOR THE TIBIAL NERVE, RESPECTIVELY). THE GROUP OF THE PATIENTS WITH THE LOWER VALUES OFMCV, WAS THE ONE WHICH SHOWED THE CLINICAL SYMTOMS AND SIGNS, OF PERIPHERAL NEUROPATHY. IN THE GROUP WITH THE COMPLICATION OF DIABETES MELLITUS MEAN VALUES WERE REDUCED (46.00 4.37 M/S FOR THE DEEP PERONEAL NERVE AND 44,36 3.79M/S FOR THE TIBIAL NERVE) WITH A FURTHER STATISTICALLY SIGNIFICANT MCV REDUCTION ONLY FOR THE TIBIAL NERVE. IN 8 PATIENTS NEUROPATHIC FINDINGS WERE RECORDING (EMG OF TIBIALIS ANTERIOR M. AND GASTROCNEMIUS M). IT LOOKS POSSIBLY FROM THE WHOLE STUDY THAT LOW HEAMATOCRITE VALUES ARE RELATED TO THE PATHOGENESIS OF THE NEUROPATHY.

Grantor dc:publisher

University of Patras

Year dc:date

1989

Author dc:creator

• Παπανικολάου, Δημήτρης

• ELECTROMYOGRAPHY AND B-THALASSEMIA
• ELECTRONEUROGRAPHY AND B-THALASSEMIA
• NEUROLOGICAL MANIFESTATIONS OF B-THALASSEMIA
• PERIFERAL NEUROPATHY IN B-THALASSEMIA
• ΗΛΕΚΤΡΟΜΥΟΓΡΑΦΙΑ ΣΤΗ Β-ΘΑΛΑΣΣΑΙΜΙΑ
• ΗΛΕΚΤΡΟΝΕΥΡΟΓΡΑΦΙΑ ΣΤΗ Β-ΘΑΛΑΣΣΑΙΜΙΑ
• ΝΕΥΡΟΛΟΓΙΚΕΣ ΕΚΔΗΛΩΣΕΙΣ ΣΤΗ Β-ΘΑΛΑΣΣΑΙΜΙΑ
• ΠΕΡΙΦΕΡΙΚΗ ΝΕΥΡΟΠΑΘΕΙΑ ΣΤΗ Β-ΘΑΛΑΣΣΑΙΜΙΑ
• Ιατρική και Επιστήμες Υγείας
• Κλινική Ιατρική
• Medical and Health Sciences
• Clinical Medicine

Language dc:language

gre

Identifier

10.12681/eadd/1100

OAI identifier oai:identifier

oai:10442/1100