ΙΣΤΟΠΑΘΟΛΟΓΙΚΗ ΜΕΛΕΤΗ ΤΩΝ ΑΛΛΟΙΩΣΕΩΝ ΤΟΥ ΕΓΚΕΦΑΛΟΥ ΤΟΥ ΗΠΑΤΟΣ ΚΑΙ ΤΩΝ ΝΕΦΡΩΝ ΑΠΟ ΤΟΞΙΚΕΣ ΔΟΣΕΙΣ ΦΑΙΝΥΤΟΙΝΗΣ ΣΤΑ ΚΟΥΝΕΛΙΑ

IN THIS STUDY 32 WHITE NEW ZEALAND RABBITS WERE EXAMINED FOR TOXIC EFFECTS OF PHENYTOIN, IN THE BRAIN, LIVER AND KIDNEYS IN RELATION TO THE CONCENTRATION OF PHENYTOIN IN THEIR BLOOD. ALL MEASUREMENTS WERE MADE USING R.I.A. METHOD. THE RABBITS WERE DIVIDED INTO THREE GROUPS, A,B AND C. PHENYTOIN WAS GIVEN INTRAMUSCULARY IN GROUPS A AND B IN DOSES OF 100 MG AND 200 PER KG BODY WEIGHT RESPECTIVELY AND 250 MG PER KG BODY WEIGHT IN GROUP C INTRAPERITONEALLY DAILY FOR A PERIOD OF 20 DAYS. IN ORDER TO RECORD CLINICAL SYMPTOMS, OBSERVATIONS OF THE RABBITSWERE MADE EVERY DAY FOR SEVERAL HOURS AND MEASUREMENTS OF THE CONCENTRATION OFPHENYTOIN IN THE BLOOD WERE MADE, IN SAMPLES TAKEN EVERY WEEK. (SHORTENED)

Grantor dc:publisher

Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ)

Year dc:date

1987

Author dc:creator

• Πέγιος, Γεώργιος

• PATHOLOGY OF THE BRAIN
• PATHOLOGY OF THE KIDNEYS
• PATHOLOGY OF THE LIVER
• Phenytoin
• Rabbits
• ΙΣΤΟΠΑΘΟΛΟΓΙΑ ΕΓΚΕΦΑΛΟΥ
• ΙΣΤΟΠΑΘΟΛΟΓΙΑ ΗΠΑΤΟΣ
• ΙΣΤΟΠΑΘΟΛΟΓΙΑ ΝΕΦΡΩΝ
• Κουνέλια
• Φαινυτοΐνη
• Γεωπονικές Επιστήμες και Κτηνιατρική
• Agricultural and Veterinary Sciences
• Κτηνιατρική
• Veterinary Science

Language dc:language

gre

Identifier

10.12681/eadd/0653

OAI identifier oai:identifier

oai:10442/0653