Design of an adventitial type reinforcement of prosthetic vascular grafts through mechanically affirmed material and structure modulation

The high occurrence of vascular disease in the 20th century has been the driving force for researchers to produce a successful small diameter synthetic graft. Large diameter synthetic grafts remain patent for extended periods due to high flow rate, while smaller diameter grafts occlude more readily. Mechanical property mismatch between graft and host artery has been cited as one of the major factors that contribute to graft occlusion. It has thus been important to develop a readily available graft that is accepted by the body and does not cause flow abnormalities and stress-concentrations at graft-artery junctions. The object of this project was to ascertain the effect of an adventitial reinforcement on elastic compliance of synthetic porous polyurethane grafts.

Grantor dc:publisher.institution

Department of Medicine

Year dc:date.issued

2001

Author dc:creator

• Millam, Ross David Alexander

Advisors dc:contributor.advisor

• Zilla, Peter
• Bezuidenhout, Deon

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/11622

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/11622