Biopterin metabolism in health and disease

Tetrahydrobiopterin metabolism in man has been studied in three ways. Firstly the serum concentration of biopterin derivatives was measured using a Crithidia fasiculata assay. Secondly the urine concentration of neopterin and biopterin was estimated by high performance liquid chromatography. Thirdly the urine concentration of tetrahydrobiopterin was determined by an enzymatic assay using phenylalanine hydroxylase. The results obtained have been correlated with various disease states and previous studies of tetrahydrobiopterin metabolism so as to extend our understanding of tetrahydrobiopterin metabolism...

Name dc:type.qualificationname

masters

Level dc:type.qualificationlevel

masters

Grantor dc:publisher.institution

Aston University

Year dc:date.issued

1982

Author dc:creator

• Al-Beir, Ayser Yousif Mustafa

DOI dc:identifier.doi

https://doi.org/10.48780/publications.aston.ac.uk.00011694

OAI identifier oai:identifier

oai:publications.aston.ac.uk:11694