{"id":{"repo_id":"aston","oai_identifier":"oai:publications.aston.ac.uk:11694"},"canonical_url":"https://search.dev.ndltd.org/etd/aston/oai:publications.aston.ac.uk:11694","repository":{"repo_id":"aston","name":"Aston University","base_url":"https://publications.aston.ac.uk/cgi/oai2"},"display":{"title":"Biopterin metabolism in health and disease","abstract":"Tetrahydrobiopterin metabolism in man has been studied in three ways. Firstly the serum concentration of biopterin derivatives was measured using a Crithidia fasiculata assay. Secondly the urine concentration of neopterin and biopterin was estimated by high performance liquid chromatography. Thirdly the urine concentration of tetrahydrobiopterin was determined by an enzymatic assay using phenylalanine hydroxylase. The results obtained have been correlated with various disease states and previous studies of tetrahydrobiopterin metabolism so as to extend our understanding of tetrahydrobiopterin metabolism...","abstract_html":"Tetrahydrobiopterin metabolism in man has been studied in three ways. Firstly the serum concentration of biopterin derivatives was measured using a Crithidia fasiculata assay. Secondly the urine concentration of neopterin and biopterin was estimated by high performance liquid chromatography. Thirdly the urine concentration of tetrahydrobiopterin was determined by an enzymatic assay using phenylalanine hydroxylase. The results obtained have been correlated with various disease states and previous studies of tetrahydrobiopterin metabolism so as to extend our understanding of tetrahydrobiopterin metabolism...","abstract_has_math":false,"creators":["Al-Beir, Ayser Yousif Mustafa"],"institution":"Aston University","degree_name":"masters","degree_level":"masters","degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1982,"date_issued":"1982","date_published":"1982","updated_at":"2026-07-24T01:01:33Z","subjects":[],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://doi.org/10.48780/publications.aston.ac.uk.00011694","outbound_label":"DOI","outbound_source":"dc:identifier.doi"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Al-Beir, Ayser Yousif Mustafa"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["1982"]},{"key":"dc:date.issued","label":"Date","values":["1982"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Chemical Engineering & Applied Chemistry"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["Aston University"]},{"key":"dc:relation.isreferencedby","label":"Dc Relation Isreferencedby","values":["https://publications.aston.ac.uk/id/eprint/11694/"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["masters"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["masters"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.doi","label":"DOI","values":["10.48780/publications.aston.ac.uk.00011694"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://publications.aston.ac.uk/id/eprint/11694/1/A.Y.M._Al-Beir_1982_reduced.pdf"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Tetrahydrobiopterin metabolism in man has been studied in three ways. Firstly the serum concentration of biopterin derivatives was measured using a Crithidia fasiculata assay. Secondly the urine concentration of neopterin and biopterin was estimated by high performance liquid chromatography. Thirdly the urine concentration of tetrahydrobiopterin was determined by an enzymatic assay using phenylalanine hydroxylase. The results obtained have been correlated with various disease states and previous studies of tetrahydrobiopterin metabolism so as to extend our understanding of tetrahydrobiopterin metabolism..."]},{"key":"dc:format","label":"Dc Format","values":["text"]},{"key":"dc:title","label":"Title","values":["Biopterin metabolism in health and disease"]}]}],"canonical_facts":{"dc:creator":["Al-Beir, Ayser Yousif Mustafa"],"dc:date":["1982"],"dc:date.issued":["1982"],"dc:description.abstract":["Tetrahydrobiopterin metabolism in man has been studied in three ways. Firstly the serum concentration of biopterin derivatives was measured using a Crithidia fasiculata assay. Secondly the urine concentration of neopterin and biopterin was estimated by high performance liquid chromatography. Thirdly the urine concentration of tetrahydrobiopterin was determined by an enzymatic assay using phenylalanine hydroxylase. The results obtained have been correlated with various disease states and previous studies of tetrahydrobiopterin metabolism so as to extend our understanding of tetrahydrobiopterin metabolism..."],"dc:format":["text"],"dc:identifier.doi":["10.48780/publications.aston.ac.uk.00011694"],"dc:identifier.uri":["https://publications.aston.ac.uk/id/eprint/11694/1/A.Y.M._Al-Beir_1982_reduced.pdf"],"dc:publisher.department":["Chemical Engineering & Applied Chemistry"],"dc:publisher.institution":["Aston University"],"dc:relation.isreferencedby":["https://publications.aston.ac.uk/id/eprint/11694/"],"dc:title":["Biopterin metabolism in health and disease"],"dc:type":["Thesis"],"dc:type.qualificationlevel":["masters"],"dc:type.qualificationname":["masters"]},"updated_at":"2026-07-24T01:01:33Z"}