Asymmetrische Synthese funktionalisierter Homoallyl- und Homopropargylalkohole mittels der Sulfoximin-Route

This dissertation describes new methods of asymmetric synthesis of diastereomeric and enantiomeric pure allylic alcohols. Via the sulfoximine-route by Gais et al. new chiral homoallyllic alcohols were synthesized. Elimination of the sulfoximine-group lead to optically pure homopropargylic alcohols. Via Nickel-catalysed cross-coupling reactions (homogenoes and heterogenoes Catalysis) of the homoallylic alcohols additional allylic silane- and allylic alcohol- groups were generated. Intramolecular cyclisation of the chiral allylic silanes with acetals yielded optically pure tetrasubstituted tetrahydrofurans.

Grantor dc:publisher

Publikationsserver der RWTH Aachen University

Year dc:date

2000

Author dc:creator

• Woo, Chang-Wan

Contributors dc:contributor

• Gais, Hans-Joachim

• info:eu-repo/classification/ddc/540
• Chemie
• Homoallyl-Verbindungen
• Allylalkoholderivate
• Asymmetrische Synthese
• Sulfoximide
• Allylgruppe
• Hydroxyalkylierung
• Propinolderivate
• Funktione

Statement dc:rights

• info:eu-repo/semantics/openAccess

Language dc:language

ger

Identifier

https://publications.rwth-aachen.de/search?p=id:%22RWTH-CONV-121920%22

OAI identifier oai:identifier

oai:publications.rwth-aachen.de:60197