Microbiological profile of surgical site infections in orthopedic surgery at the university teaching hospital; Lusaka, Zambia.
type: CreativeWork
description: Background and purpose: Surgical site infection (SSI) is the infection to the surgical site occurring within a year of surgery (if an implant is used) or within 30 days if no implant is used. SSI is a known cause of poor outcomes, increased healthcare cost on patients, sometimes leading to significant disability and even death, following orthopaedic surgery the world over. The microbiological profile of SSI following orthopaedic surgery at University Teaching Hospital (UTH) in Lusaka, Zambia was unknown as, before this study, no such research had been conducted. The SSI following orthopaedic surgery at UTH was seen as a growing problem with the possibility of antimicrobial resistance. Hence, this study set out to investigate SSI following orthopaedic surgery in this setting, to determine the causative microorganisms, their prevalence and antimicrobial sensitivity patterns. Methods: A cross-sectional study was conducted at UTH, Lusaka, Zambia from March 2019 to March 2020. A structured questionnaire was used to collect data and sampling was done using a systematic random sampling after getting informed consent. Using AMIES pus swabs, samples were collected and sent to the microbiology laboratory at UTH for microscopy, culture and sensitivity studies. All cultures were done on three primary media MacConky, chocolate and blood agar, and the antimicrobial sensitivity studies for the cultured microorganisms were done on Mueller Hinton agar. STATA statistical software version 13 was used for the analysis of results obtained to come up with a microbiological profile of SSI. Results: A total of 119 (79 male and 40 female) participants were recruited. The mean age was 31.75 (SD, 17.07) of the participants; 66.4% of the participants were male. The HIV prevalence was 15.1%. Out of 119 participants, 100 had culture-positive results giving a prevalence of 84.0%. S. aureus was the most prevalent 35 (29.4%) causative microorganism, with MRSA comprising 54.3% of the S. aureus. Othe…
abstract: Background and purpose: Surgical site infection (SSI) is the infection to the surgical site occurring within a year of surgery (if an implant is used) or within 30 days if no implant is used. SSI is a known cause of poor outcomes, increased healthcare cost on patients, sometimes leading to significant disability and even death, following orthopaedic surgery the world over. The microbiological profile of SSI following orthopaedic surgery at University Teaching Hospital (UTH) in Lusaka, Zambia was unknown as, before this study, no such research had been conducted. The SSI following orthopaedic surgery at UTH was seen as a growing problem with the possibility of antimicrobial resistance. Hence, this study set out to investigate SSI following orthopaedic surgery in this setting, to determine the causative microorganisms, their prevalence and antimicrobial sensitivity patterns. Methods: A cross-sectional study was conducted at UTH, Lusaka, Zambia from March 2019 to March 2020. A structured questionnaire was used to collect data and sampling was done using a systematic random sampling after getting informed consent. Using AMIES pus swabs, samples were collected and sent to the microbiology laboratory at UTH for microscopy, culture and sensitivity studies. All cultures were done on three primary media MacConky, chocolate and blood agar, and the antimicrobial sensitivity studies for the cultured microorganisms were done on Mueller Hinton agar. STATA statistical software version 13 was used for the analysis of results obtained to come up with a microbiological profile of SSI. Results: A total of 119 (79 male and 40 female) participants were recruited. The mean age was 31.75 (SD, 17.07) of the participants; 66.4% of the participants were male. The HIV prevalence was 15.1%. Out of 119 participants, 100 had culture-positive results giving a prevalence of 84.0%. S. aureus was the most prevalent 35 (29.4%) causative microorganism, with MRSA comprising 54.3% of the S. aureus. Othe…
author: Kandila, Joel
language: en
keywords: Surgical Site Infection., Orthopedic Surgery., Wounds and Injuries--Diagnosis.
date published: 2020
date modified: 2026-07-27T22:06:02Z
provider: University of Zambia
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: The University of Zambia