{"id":{"repo_id":"zambia","oai_identifier":"oai:dspace.unza.zm:123456789/5240"},"canonical_url":"https://search.dev.ndltd.org/etd/zambia/oai:dspace.unza.zm:123456789/5240","repository":{"repo_id":"zambia","name":"University of Zambia","base_url":"https://dspace.unza.zm/server/oai/request"},"display":{"title":"Factors influencing non-adeherence to tuberculosis treatment in TB/HIV co-infected adults at the University Teaching Hospital,Lusaka,Zambia","abstract":"Zambia is a high TB/HIV prevalence country. The aim of this study was to explore barriers to TB treatment adherence and determine the prevalence of non-adherence in the Zambian capital of Lusaka. The factors under study were socio-economic and demographic, service-related and disease and treatment related factors. A cross-sectional study was conducted on 239 TB patients co-infected with HIV, using an interviewer-administered structured questionnaire. Chi-square test was used for bivariate analysis of the outcome and independent variables. Logistic regression was used to obtain the best model because the study had a binary outcome. The prevalence of non-adherence was found to be 8.4%. Factors that influenced adherence to TB treatment were response to treatment (p=0.038) and the affordability of transport costs (p<0.001) to the health-care facilities. The odds of a patient defaulting treatment due to their response to the TB drugs were up to 17 times higher for those with a poor response than those of a patient with an average response. This study found a low level of non-adherence to TB treatment. Economic constraints and treatment factors pose a threat of non-adherence to TB treatment. Social support and intensive counseling might help to mitigate this threat. Further studies addressing sensitization, intervention and their impact assessment are recommended. Keywords: Tuberculosis, HIV/AIDS, Non-adherence, co-infection","abstract_html":"Zambia is a high TB/HIV prevalence country. The aim of this study was to explore barriers to TB treatment adherence and determine the prevalence of non-adherence in the Zambian capital of Lusaka. The factors under study were socio-economic and demographic, service-related and disease and treatment related factors. A cross-sectional study was conducted on 239 TB patients co-infected with HIV, using an interviewer-administered structured questionnaire. Chi-square test was used for bivariate analysis of the outcome and independent variables. Logistic regression was used to obtain the best model because the study had a binary outcome. The prevalence of non-adherence was found to be 8.4%. Factors that influenced adherence to TB treatment were response to treatment (p=0.038) and the affordability of transport costs (p&lt;0.001) to the health-care facilities. The odds of a patient defaulting treatment due to their response to the TB drugs were up to 17 times higher for those with a poor response than those of a patient with an average response. This study found a low level of non-adherence to TB treatment. Economic constraints and treatment factors pose a threat of non-adherence to TB treatment. Social support and intensive counseling might help to mitigate this threat. Further studies addressing sensitization, intervention and their impact assessment are recommended. Keywords: Tuberculosis, HIV/AIDS, Non-adherence, co-infection","abstract_has_math":false,"creators":["Ramadhani, Asha"],"institution":"The University of Zambia","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2017,"date_issued":"2017","date_published":"2017","updated_at":"2026-07-27T22:06:29Z","subjects":["TB/HIV--Treatment--Zambia","TB/HIV--Adherence--Zambia"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://dspace.unza.zm/handle/123456789/5240","outbound_label":"Repository record","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Ramadhani, Asha"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2018-07-11T09:23:31Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2018-07-11T09:23:31Z"]},{"key":"dc:date.issued","label":"Date","values":["2017"]},{"key":"dc:publisher","label":"Institution","values":["The University of Zambia"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["TB/HIV--Treatment--Zambia","TB/HIV--Adherence--Zambia"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://dspace.unza.zm/handle/123456789/5240"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["THESIS MSC (EPIDEMIOLOGY)"]},{"key":"dc:description.abstract","label":"Abstract","values":["Zambia is a high TB/HIV prevalence country. The aim of this study was to explore barriers to TB treatment adherence and determine the prevalence of non-adherence in the Zambian capital of Lusaka. The factors under study were socio-economic and demographic, service-related and disease and treatment related factors. A cross-sectional study was conducted on 239 TB patients co-infected with HIV, using an interviewer-administered structured questionnaire. Chi-square test was used for bivariate analysis of the outcome and independent variables. Logistic regression was used to obtain the best model because the study had a binary outcome. The prevalence of non-adherence was found to be 8.4%. Factors that influenced adherence to TB treatment were response to treatment (p=0.038) and the affordability of transport costs (p<0.001) to the health-care facilities. The odds of a patient defaulting treatment due to their response to the TB drugs were up to 17 times higher for those with a poor response than those of a patient with an average response. This study found a low level of non-adherence to TB treatment. Economic constraints and treatment factors pose a threat of non-adherence to TB treatment. Social support and intensive counseling might help to mitigate this threat. Further studies addressing sensitization, intervention and their impact assessment are recommended. Keywords: Tuberculosis, HIV/AIDS, Non-adherence, co-infection"]},{"key":"dc:title","label":"Title","values":["Factors influencing non-adeherence to tuberculosis treatment in TB/HIV co-infected adults at the University Teaching Hospital,Lusaka,Zambia"]}]}],"canonical_facts":{"dc:creator":["Ramadhani, Asha"],"dc:date.accessioned":["2018-07-11T09:23:31Z"],"dc:date.available":["2018-07-11T09:23:31Z"],"dc:date.issued":["2017"],"dc:description":["THESIS MSC (EPIDEMIOLOGY)"],"dc:description.abstract":["Zambia is a high TB/HIV prevalence country. The aim of this study was to explore barriers to TB treatment adherence and determine the prevalence of non-adherence in the Zambian capital of Lusaka. The factors under study were socio-economic and demographic, service-related and disease and treatment related factors. A cross-sectional study was conducted on 239 TB patients co-infected with HIV, using an interviewer-administered structured questionnaire. Chi-square test was used for bivariate analysis of the outcome and independent variables. Logistic regression was used to obtain the best model because the study had a binary outcome. The prevalence of non-adherence was found to be 8.4%. Factors that influenced adherence to TB treatment were response to treatment (p=0.038) and the affordability of transport costs (p<0.001) to the health-care facilities. The odds of a patient defaulting treatment due to their response to the TB drugs were up to 17 times higher for those with a poor response than those of a patient with an average response. This study found a low level of non-adherence to TB treatment. Economic constraints and treatment factors pose a threat of non-adherence to TB treatment. Social support and intensive counseling might help to mitigate this threat. Further studies addressing sensitization, intervention and their impact assessment are recommended. Keywords: Tuberculosis, HIV/AIDS, Non-adherence, co-infection"],"dc:identifier.uri":["http://dspace.unza.zm/handle/123456789/5240"],"dc:language.iso":["en"],"dc:publisher":["The University of Zambia"],"dc:subject":["TB/HIV--Treatment--Zambia","TB/HIV--Adherence--Zambia"],"dc:title":["Factors influencing non-adeherence to tuberculosis treatment in TB/HIV co-infected adults at the University Teaching Hospital,Lusaka,Zambia"],"dc:type":["Thesis"]},"updated_at":"2026-07-27T22:06:29Z"}