{"id":{"repo_id":"york","oai_identifier":"oai:yorkspace.library.yorku.ca:10315/41602"},"canonical_url":"https://search.dev.ndltd.org/etd/york/oai:yorkspace.library.yorku.ca:10315/41602","repository":{"repo_id":"york","name":"York University","base_url":"https://yorkspace.library.yorku.ca/oai/request"},"display":{"title":"Mismatch Negativity as a Marker of Auditory Pattern Separation Integrity in Aging","abstract":"How does auditory perception interact with precision in memory (i.e., mnemonic discrimination) in aging? This study examined how the mismatch negativity (MMN), an electrophysiological marker of change detection and encoding, relates to age differences in mnemonic discrimination. The MMN was recorded from 33 young (18–32 years, 18 females) and 30 older (55–86 years, 14 females) adults in a passive oddball paradigm using tone sequences. Participants then completed an incidental recognition test for old targets against similar lures and dissimilar foils. Older adults showed attenuated MMN amplitudes and poorer performance discriminating targets from lures and foils than young adults. Across participants, smaller MMN amplitude predicted worse recognition performance. Notably, MMN amplitude partially explained age-related declines in target-lure discriminability, but not target-foil discriminability. Findings reinforce the MMN as a marker of pattern separation integrity, and clarify how age-related declines in mnemonic discrimination are explained by age differences at encoding.","abstract_html":"How does auditory perception interact with precision in memory (i.e., mnemonic discrimination) in aging? This study examined how the mismatch negativity (MMN), an electrophysiological marker of change detection and encoding, relates to age differences in mnemonic discrimination. The MMN was recorded from 33 young (18–32 years, 18 females) and 30 older (55–86 years, 14 females) adults in a passive oddball paradigm using tone sequences. Participants then completed an incidental recognition test for old targets against similar lures and dissimilar foils. Older adults showed attenuated MMN amplitudes and poorer performance discriminating targets from lures and foils than young adults. Across participants, smaller MMN amplitude predicted worse recognition performance. Notably, MMN amplitude partially explained age-related declines in target-lure discriminability, but not target-foil discriminability. Findings reinforce the MMN as a marker of pattern separation integrity, and clarify how age-related declines in mnemonic discrimination are explained by age differences at encoding.","abstract_has_math":false,"creators":["Chow, Ricky Ka Lok"],"institution":null,"degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Rosenbaum, Shayna"],"committee_chairs":[],"committee_members":[],"year":2023,"date_issued":"2023-12-08","date_published":"2023-12-08","updated_at":"2026-07-24T06:33:34Z","subjects":["Psychology","Neurosciences","Cognitive psychology"],"languages":["en"],"rights":["Author owns copyright, except where explicitly noted. Please contact the author directly with licensing requests."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/10315/41602","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Rosenbaum, Shayna"]},{"key":"dc:creator","label":"Author","values":["Chow, Ricky Ka Lok"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2023-12-08T14:22:49Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2023-12-08T14:22:49Z"]},{"key":"dc:date.issued","label":"Date","values":["2023-12-08"]},{"key":"dc:type","label":"Dc Type","values":["Electronic Thesis or Dissertation"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Psychology","Neurosciences","Cognitive psychology"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["Author owns copyright, except where explicitly noted. Please contact the author directly with licensing requests."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://hdl.handle.net/10315/41602"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["How does auditory perception interact with precision in memory (i.e., mnemonic discrimination) in aging? This study examined how the mismatch negativity (MMN), an electrophysiological marker of change detection and encoding, relates to age differences in mnemonic discrimination. The MMN was recorded from 33 young (18–32 years, 18 females) and 30 older (55–86 years, 14 females) adults in a passive oddball paradigm using tone sequences. Participants then completed an incidental recognition test for old targets against similar lures and dissimilar foils. Older adults showed attenuated MMN amplitudes and poorer performance discriminating targets from lures and foils than young adults. Across participants, smaller MMN amplitude predicted worse recognition performance. Notably, MMN amplitude partially explained age-related declines in target-lure discriminability, but not target-foil discriminability. Findings reinforce the MMN as a marker of pattern separation integrity, and clarify how age-related declines in mnemonic discrimination are explained by age differences at encoding."]},{"key":"dc:title","label":"Title","values":["Mismatch Negativity as a Marker of Auditory Pattern Separation Integrity in Aging"]}]}],"canonical_facts":{"dc:contributor.advisor":["Rosenbaum, Shayna"],"dc:creator":["Chow, Ricky Ka Lok"],"dc:date.accessioned":["2023-12-08T14:22:49Z"],"dc:date.available":["2023-12-08T14:22:49Z"],"dc:date.issued":["2023-12-08"],"dc:description.abstract":["How does auditory perception interact with precision in memory (i.e., mnemonic discrimination) in aging? This study examined how the mismatch negativity (MMN), an electrophysiological marker of change detection and encoding, relates to age differences in mnemonic discrimination. The MMN was recorded from 33 young (18–32 years, 18 females) and 30 older (55–86 years, 14 females) adults in a passive oddball paradigm using tone sequences. Participants then completed an incidental recognition test for old targets against similar lures and dissimilar foils. Older adults showed attenuated MMN amplitudes and poorer performance discriminating targets from lures and foils than young adults. Across participants, smaller MMN amplitude predicted worse recognition performance. Notably, MMN amplitude partially explained age-related declines in target-lure discriminability, but not target-foil discriminability. Findings reinforce the MMN as a marker of pattern separation integrity, and clarify how age-related declines in mnemonic discrimination are explained by age differences at encoding."],"dc:identifier.uri":["https://hdl.handle.net/10315/41602"],"dc:language":["en"],"dc:rights":["Author owns copyright, except where explicitly noted. Please contact the author directly with licensing requests."],"dc:subject":["Psychology","Neurosciences","Cognitive psychology"],"dc:title":["Mismatch Negativity as a Marker of Auditory Pattern Separation Integrity in Aging"],"dc:type":["Electronic Thesis or Dissertation"]},"updated_at":"2026-07-24T06:33:34Z"}