{"id":{"repo_id":"wvu","oai_identifier":"oai:researchrepository.wvu.edu:etd-2300"},"canonical_url":"https://search.dev.ndltd.org/etd/wvu/oai:researchrepository.wvu.edu:etd-2300","repository":{"repo_id":"wvu","name":"West Virginia University","base_url":"https://researchrepository.wvu.edu/do/oai/"},"display":{"title":"Green tea antioxidants inhibition of oxidation and mutation","abstract":"Green tea is a complex mixture containing several major potent antioxidants e.g., flavins and/or polyphenols. These antioxidants in green tea may react directly or indirectly with strong oxidizers e.g. peroxynitrite or its constituents (superoxide or nitric oxide). Green tea antioxidants can destroy the oxidants. Based on a simple chemical interaction of peroxynitrite (OONO-) and luminol, blue light is produced upon oxidation. It was shown that green tea and constituents have light inhibitory capabilities. In order to show the possible beneficial effects of green tea with DNA, plasmids were chosen to determine whether or not green tea was also capable of preventing oxidative based damage (mutations). It can be deduced that there are multiple levels of antioxidative protection. First, antioxidants can destroy the pieces of peroxynitrite (·O2 and ·NO), protect from peroxynitrite itself, or protect from the damage caused to DNA by peroxynitrite.","abstract_html":"Green tea is a complex mixture containing several major potent antioxidants e.g., flavins and/or polyphenols. These antioxidants in green tea may react directly or indirectly with strong oxidizers e.g. peroxynitrite or its constituents (superoxide or nitric oxide). Green tea antioxidants can destroy the oxidants. Based on a simple chemical interaction of peroxynitrite (OONO-) and luminol, blue light is produced upon oxidation. It was shown that green tea and constituents have light inhibitory capabilities. In order to show the possible beneficial effects of green tea with DNA, plasmids were chosen to determine whether or not green tea was also capable of preventing oxidative based damage (mutations). It can be deduced that there are multiple levels of antioxidative protection. First, antioxidants can destroy the pieces of peroxynitrite (·O2 and ·NO), protect from peroxynitrite itself, or protect from the damage caused to DNA by peroxynitrite.","abstract_has_math":false,"creators":["McConnell, Paul Stout"],"institution":null,"degree_name":"MS","degree_level":"Thesis","degree_discipline":"Biochemistry","degree_department":null,"school":null,"contributors":["Knox Van Dyke."],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2001,"date_issued":"2001-08-01T07:00:00Z","date_published":"2001-08-01T07:00:00Z","updated_at":"2026-07-24T06:15:31Z","subjects":["Genetics","Biochemistry","Molecular biology"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["https://researchrepository.wvu.edu/etd/1297"],"render_values":[{"text":"https://researchrepository.wvu.edu/etd/1297","href":"https://researchrepository.wvu.edu/etd/1297","code":true}]}]},"links":{"outbound_url":"https://doi.org/10.33915/etd.1297","outbound_label":"DOI","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Knox Van Dyke."]},{"key":"dc:creator","label":"Author","values":["McConnell, Paul Stout"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2019-01-17T08:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Biochemistry"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["MS"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Genetics","Biochemistry","Molecular biology"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://doi.org/10.33915/etd.1297","https://researchrepository.wvu.edu/etd/1297"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Green tea is a complex mixture containing several major potent antioxidants e.g., flavins and/or polyphenols. These antioxidants in green tea may react directly or indirectly with strong oxidizers e.g. peroxynitrite or its constituents (superoxide or nitric oxide). Green tea antioxidants can destroy the oxidants. Based on a simple chemical interaction of peroxynitrite (OONO-) and luminol, blue light is produced upon oxidation. It was shown that green tea and constituents have light inhibitory capabilities. In order to show the possible beneficial effects of green tea with DNA, plasmids were chosen to determine whether or not green tea was also capable of preventing oxidative based damage (mutations). It can be deduced that there are multiple levels of antioxidative protection. First, antioxidants can destroy the pieces of peroxynitrite (·O2 and ·NO), protect from peroxynitrite itself, or protect from the damage caused to DNA by peroxynitrite."]},{"key":"dc:title","label":"Title","values":["Green tea antioxidants inhibition of oxidation and mutation"]}]}],"canonical_facts":{"dc:contributor":["Knox Van Dyke."],"dc:creator":["McConnell, Paul Stout"],"dc:date.available":["2019-01-17T08:00:00Z"],"dc:description.abstract":["Green tea is a complex mixture containing several major potent antioxidants e.g., flavins and/or polyphenols. These antioxidants in green tea may react directly or indirectly with strong oxidizers e.g. peroxynitrite or its constituents (superoxide or nitric oxide). Green tea antioxidants can destroy the oxidants. Based on a simple chemical interaction of peroxynitrite (OONO-) and luminol, blue light is produced upon oxidation. It was shown that green tea and constituents have light inhibitory capabilities. In order to show the possible beneficial effects of green tea with DNA, plasmids were chosen to determine whether or not green tea was also capable of preventing oxidative based damage (mutations). It can be deduced that there are multiple levels of antioxidative protection. First, antioxidants can destroy the pieces of peroxynitrite (·O2 and ·NO), protect from peroxynitrite itself, or protect from the damage caused to DNA by peroxynitrite."],"dc:identifier":["https://doi.org/10.33915/etd.1297","https://researchrepository.wvu.edu/etd/1297"],"dc:subject":["Genetics","Biochemistry","Molecular biology"],"dc:title":["Green tea antioxidants inhibition of oxidation and mutation"],"thesis:degree_discipline":["Biochemistry"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["MS"]},"updated_at":"2026-07-24T06:15:31Z"}