Segmentation and Strain Mapping of a Beating Heart

<p>Conventional methods of estimating deformation optically often compare image intensities before and after deformation to help estimate the strain fields. However, these current meth ods often introduce undesirable error that propagates through the system, growing larger through each strain calculation. These errors create false, concentrated regions of strain throughout the image. Additionally, gathering and evaluating images in three- and four dimensional space creates even more difficulty for conventional methods. Here, by imple menting new techniques of gathering four-dimensional ultrasound data sets and calculating deformation fields with traditional errors reduced three-fold, four-dimensional images were evaluated to create a novel visualization tool used for representing the strains in a four dimensional modeling world. In general, this computer program has applications across a wide range of disciplines.</p>

Name thesis:degree_name

Master of Science (MS)

Level thesis:degree_level

Thesis

Discipline thesis:degree_discipline

Mechanical Engineering & Materials Science

Year dc:date.available

2015

Author dc:creator

• Middleton, Kenna

Contributors dc:contributor

• Dr. Phil Bayly
• Dr. Guy Genin, Dr. Robert Pless, Dr. Srikanth Singamaneni

• Strain mapping
• mouse heart
• Engineering
• Other Medicine and Health Sciences

Statement dc:rights

• I have not registered my thesis with the U.S. Copyright Office, and do not intend to.

Language dc:language

English (en)

Identifier

https://openscholarship.wustl.edu/eng_etds/123

OAI identifier oai:identifier

oai:openscholarship.wustl.edu:eng_etds-1123