{"id":{"repo_id":"wurz-thes","oai_identifier":"oai:opus.bibliothek.uni-wuerzburg.de:999"},"canonical_url":"https://search.dev.ndltd.org/etd/wurz-thes/oai:opus.bibliothek.uni-wuerzburg.de:999","repository":{"repo_id":"wurz-thes","name":"Universität Wüzburg","base_url":"https://opus.bibliothek.uni-wuerzburg.de/oai"},"display":{"title":"Regulation der Chemokinexpression in humanen zerebralen Endothelzellen","abstract":"Humane zerebrale Endothelzellen sind in vitro in der Lage nach Stimulation mit proinflammatorischen Zytokinen Chemokine zu produzieren. Diese sind von Bedeutung in der Entwicklung von entzündlichen ZNS-Erkrankungen. So scheinen zerebrale Endothelzellen neben Astrozyten und Mikroglia als Produzenten dieser Schlüsselmoleküle zu fungieren.","abstract_html":"Humane zerebrale Endothelzellen sind in vitro in der Lage nach Stimulation mit proinflammatorischen Zytokinen Chemokine zu produzieren. Diese sind von Bedeutung in der Entwicklung von entzündlichen ZNS-Erkrankungen. So scheinen zerebrale Endothelzellen neben Astrozyten und Mikroglia als Produzenten dieser Schlüsselmoleküle zu fungieren.","abstract_has_math":false,"creators":["Klein, Oliver"],"institution":"Universität Würzburg","degree_name":null,"degree_level":"thesis.doctoral","degree_discipline":null,"degree_department":null,"school":null,"contributors":["Rieckmann, Peter"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2005,"date_issued":"2005-01-11","date_published":"2005-01-11","updated_at":"2026-07-24T06:11:30Z","subjects":["Blut-Hirn-Schranke","zerebrale Endothelzellen","Chemokine","blood-brain-barrier","cerebral endothelial cells","chemokines"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/999","outbound_label":"Repository record","outbound_source":"source_url"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Rieckmann, Peter"]},{"key":"dc:creator","label":"Author","values":["Klein, Oliver"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:publisher","label":"Institution","values":["Universität Würzburg"]},{"key":"dc:type","label":"Dc Type","values":["doctoralThesis"]},{"key":"thesis:degree_level","label":"Degree Level","values":["thesis.doctoral"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Universität Würzburg"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Blut-Hirn-Schranke","zerebrale Endothelzellen","Chemokine","blood-brain-barrier","cerebral endothelial cells","chemokines"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Humane zerebrale Endothelzellen sind in vitro in der Lage nach Stimulation mit proinflammatorischen Zytokinen Chemokine zu produzieren. Diese sind von Bedeutung in der Entwicklung von entzündlichen ZNS-Erkrankungen. So scheinen zerebrale Endothelzellen neben Astrozyten und Mikroglia als Produzenten dieser Schlüsselmoleküle zu fungieren.","Human cerebral endothelial cells are able to produce chemokines after stimulation with proinflammatory cytokines. Chemokines have a pivotal role in inflammatory cns disorders. So cerebral endothelial cells seems to be another cell typ besides astrocytes and microglia, that synthesize these important molecules."]},{"key":"dc:format.medium","label":"Dc Format Medium","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Regulation der Chemokinexpression in humanen zerebralen Endothelzellen","regulation of chemokinexpression in human cerebral endothelial cells"]}]}],"canonical_facts":{"dc:contributor":["Rieckmann, Peter"],"dc:creator":["Klein, Oliver"],"dc:description.abstract":["Humane zerebrale Endothelzellen sind in vitro in der Lage nach Stimulation mit proinflammatorischen Zytokinen Chemokine zu produzieren. Diese sind von Bedeutung in der Entwicklung von entzündlichen ZNS-Erkrankungen. So scheinen zerebrale Endothelzellen neben Astrozyten und Mikroglia als Produzenten dieser Schlüsselmoleküle zu fungieren.","Human cerebral endothelial cells are able to produce chemokines after stimulation with proinflammatory cytokines. Chemokines have a pivotal role in inflammatory cns disorders. So cerebral endothelial cells seems to be another cell typ besides astrocytes and microglia, that synthesize these important molecules."],"dc:format.medium":["application/pdf"],"dc:publisher":["Universität Würzburg"],"dc:subject":["Blut-Hirn-Schranke","zerebrale Endothelzellen","Chemokine","blood-brain-barrier","cerebral endothelial cells","chemokines"],"dc:title":["Regulation der Chemokinexpression in humanen zerebralen Endothelzellen","regulation of chemokinexpression in human cerebral endothelial cells"],"dc:type":["doctoralThesis"],"thesis:degree_level":["thesis.doctoral"],"thesis:institution_name":["Universität Würzburg"]},"updated_at":"2026-07-24T06:11:30Z"}