{"id":{"repo_id":"wurz-thes","oai_identifier":"oai:opus.bibliothek.uni-wuerzburg.de:726"},"canonical_url":"https://search.dev.ndltd.org/etd/wurz-thes/oai:opus.bibliothek.uni-wuerzburg.de:726","repository":{"repo_id":"wurz-thes","name":"Universität Wüzburg","base_url":"https://opus.bibliothek.uni-wuerzburg.de/oai"},"display":{"title":"Molekulargenetische Untersuchung der chromosomalen Translokation t(11;14)(q13;q32) im Marginalzonen-B-Zell-Lymphom der Milz","abstract":"Die chromosomale Translokation t(11;14)(q13;q32), welche zu einem BCL1-Rearrangement und Cyclin D1 Überexpression führt, gehört nicht zu den molekulargenetisch nachweisbaren Merkmalen des Marginalzonen-B-Zell-Lymphoms, sondern ist stark mit dem Mantelzell-Lymphom assoziiert.","abstract_html":"Die chromosomale Translokation t(11;14)(q13;q32), welche zu einem BCL1-Rearrangement und Cyclin D1 Überexpression führt, gehört nicht zu den molekulargenetisch nachweisbaren Merkmalen des Marginalzonen-B-Zell-Lymphoms, sondern ist stark mit dem Mantelzell-Lymphom assoziiert.","abstract_has_math":false,"creators":["Lenz, Elke"],"institution":"Universität Würzburg","degree_name":null,"degree_level":"thesis.doctoral","degree_discipline":null,"degree_department":null,"school":null,"contributors":["Ott, Michaela"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2003,"date_issued":"2003-12-03","date_published":"2003-12-03","updated_at":"2026-07-24T06:11:23Z","subjects":["Marginalzonen-B-Zell-Lymphom","Translokation t(11;14)(q13;q32)","Milz","BCL1-Rearrangement","marginal zone-B-cell-Lymphoma","translocation t(11;14)(q13;q32)","spleen","BCL1 rearrangement"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/726","outbound_label":"Repository record","outbound_source":"source_url"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Ott, Michaela"]},{"key":"dc:creator","label":"Author","values":["Lenz, Elke"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:publisher","label":"Institution","values":["Universität Würzburg"]},{"key":"dc:type","label":"Dc Type","values":["doctoralThesis"]},{"key":"thesis:degree_level","label":"Degree Level","values":["thesis.doctoral"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Universität Würzburg"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Marginalzonen-B-Zell-Lymphom","Translokation t(11;14)(q13;q32)","Milz","BCL1-Rearrangement","marginal zone-B-cell-Lymphoma","translocation t(11;14)(q13;q32)","spleen","BCL1 rearrangement"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Die chromosomale Translokation t(11;14)(q13;q32), welche zu einem BCL1-Rearrangement und Cyclin D1 Überexpression führt, gehört nicht zu den molekulargenetisch nachweisbaren Merkmalen des Marginalzonen-B-Zell-Lymphoms, sondern ist stark mit dem Mantelzell-Lymphom assoziiert.","The chromosomal translocation t(11;14)(q13;q32), which leeds to a BCL1 rearrangement and an overexpression of cyclin D1 cannot be found in marginal zone B-cell lymphma but is strongly associated with the mantle cell lymphoma."]},{"key":"dc:format.medium","label":"Dc Format Medium","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Molekulargenetische Untersuchung der chromosomalen Translokation t(11;14)(q13;q32) im Marginalzonen-B-Zell-Lymphom der Milz","Moleculargenetical examination of the chromosomal translocation t(11;14)(q13;q32) in the maginal zone-B-cell-lymphoma of the spleen"]}]}],"canonical_facts":{"dc:contributor":["Ott, Michaela"],"dc:creator":["Lenz, Elke"],"dc:description.abstract":["Die chromosomale Translokation t(11;14)(q13;q32), welche zu einem BCL1-Rearrangement und Cyclin D1 Überexpression führt, gehört nicht zu den molekulargenetisch nachweisbaren Merkmalen des Marginalzonen-B-Zell-Lymphoms, sondern ist stark mit dem Mantelzell-Lymphom assoziiert.","The chromosomal translocation t(11;14)(q13;q32), which leeds to a BCL1 rearrangement and an overexpression of cyclin D1 cannot be found in marginal zone B-cell lymphma but is strongly associated with the mantle cell lymphoma."],"dc:format.medium":["application/pdf"],"dc:publisher":["Universität Würzburg"],"dc:subject":["Marginalzonen-B-Zell-Lymphom","Translokation t(11;14)(q13;q32)","Milz","BCL1-Rearrangement","marginal zone-B-cell-Lymphoma","translocation t(11;14)(q13;q32)","spleen","BCL1 rearrangement"],"dc:title":["Molekulargenetische Untersuchung der chromosomalen Translokation t(11;14)(q13;q32) im Marginalzonen-B-Zell-Lymphom der Milz","Moleculargenetical examination of the chromosomal translocation t(11;14)(q13;q32) in the maginal zone-B-cell-lymphoma of the spleen"],"dc:type":["doctoralThesis"],"thesis:degree_level":["thesis.doctoral"],"thesis:institution_name":["Universität Würzburg"]},"updated_at":"2026-07-24T06:11:23Z"}