{"id":{"repo_id":"wurz-thes","oai_identifier":"oai:opus.bibliothek.uni-wuerzburg.de:1416"},"canonical_url":"https://search.dev.ndltd.org/etd/wurz-thes/oai:opus.bibliothek.uni-wuerzburg.de:1416","repository":{"repo_id":"wurz-thes","name":"Universität Wüzburg","base_url":"https://opus.bibliothek.uni-wuerzburg.de/oai"},"display":{"title":"Das Immunglobulin kappa Repertoire der Tonsille","abstract":"Mutationen auf Vkappa Genen gewonnen aus B-Zellen aus Keimzentren der kindlichen Tonsille; Angesteuerte Motive: RGWY/WRCY; positive und negative Selektion der Mutationen; Diversifizierung der VkappaJkappa Schnittstelle durch TdT und Exonukleasen; Vergleich mit Daten vom Neonaten und Adulten.","abstract_html":"Mutationen auf Vkappa Genen gewonnen aus B-Zellen aus Keimzentren der kindlichen Tonsille; Angesteuerte Motive: RGWY/WRCY; positive und negative Selektion der Mutationen; Diversifizierung der VkappaJkappa Schnittstelle durch TdT und Exonukleasen; Vergleich mit Daten vom Neonaten und Adulten.","abstract_has_math":false,"creators":["Krasa, Julian"],"institution":"Universität Würzburg","degree_name":null,"degree_level":"thesis.doctoral","degree_discipline":null,"degree_department":null,"school":null,"contributors":["Girschick, Hermann"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2005,"date_issued":"2005-12-20","date_published":"2005-12-20","updated_at":"2026-07-24T06:11:45Z","subjects":["Immunglobulin","Vkappa","Tonsille","TdT","B-Zelle","immunoglobulin","tonsil","b-cell"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/1416","outbound_label":"Repository record","outbound_source":"source_url"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Girschick, Hermann"]},{"key":"dc:creator","label":"Author","values":["Krasa, Julian"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:publisher","label":"Institution","values":["Universität Würzburg"]},{"key":"dc:type","label":"Dc Type","values":["doctoralThesis"]},{"key":"thesis:degree_level","label":"Degree Level","values":["thesis.doctoral"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Universität Würzburg"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Immunglobulin","Vkappa","Tonsille","TdT","B-Zelle","immunoglobulin","tonsil","b-cell"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Mutationen auf Vkappa Genen gewonnen aus B-Zellen aus Keimzentren der kindlichen Tonsille; Angesteuerte Motive: RGWY/WRCY; positive und negative Selektion der Mutationen; Diversifizierung der VkappaJkappa Schnittstelle durch TdT und Exonukleasen; Vergleich mit Daten vom Neonaten und Adulten.","Mutations of Vkappa genes from germinalcenter b-cells from tonsils of children aged 5-7; The \"mutator\" and the prefered motifs for mutation RGYW/WRCY; positiv and negativ selection of mutations; TdT and exonuclease activity and diversification of the VkappaJkappa junction; Comparision of data from the neonat and the adult;"]},{"key":"dc:format.medium","label":"Dc Format Medium","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Das Immunglobulin kappa Repertoire der Tonsille","The immunoglobulin kappa repertoire of the human tonsil"]}]}],"canonical_facts":{"dc:contributor":["Girschick, Hermann"],"dc:creator":["Krasa, Julian"],"dc:description.abstract":["Mutationen auf Vkappa Genen gewonnen aus B-Zellen aus Keimzentren der kindlichen Tonsille; Angesteuerte Motive: RGWY/WRCY; positive und negative Selektion der Mutationen; Diversifizierung der VkappaJkappa Schnittstelle durch TdT und Exonukleasen; Vergleich mit Daten vom Neonaten und Adulten.","Mutations of Vkappa genes from germinalcenter b-cells from tonsils of children aged 5-7; The \"mutator\" and the prefered motifs for mutation RGYW/WRCY; positiv and negativ selection of mutations; TdT and exonuclease activity and diversification of the VkappaJkappa junction; Comparision of data from the neonat and the adult;"],"dc:format.medium":["application/pdf"],"dc:publisher":["Universität Würzburg"],"dc:subject":["Immunglobulin","Vkappa","Tonsille","TdT","B-Zelle","immunoglobulin","tonsil","b-cell"],"dc:title":["Das Immunglobulin kappa Repertoire der Tonsille","The immunoglobulin kappa repertoire of the human tonsil"],"dc:type":["doctoralThesis"],"thesis:degree_level":["thesis.doctoral"],"thesis:institution_name":["Universität Würzburg"]},"updated_at":"2026-07-24T06:11:45Z"}