{"id":{"repo_id":"whiterose","oai_identifier":"oai:etheses.whiterose.ac.uk:972"},"canonical_url":"https://search.dev.ndltd.org/etd/whiterose/oai:etheses.whiterose.ac.uk:972","repository":{"repo_id":"whiterose","name":"White Rose University Consortium","base_url":"https://etheses.whiterose.ac.uk/cgi/oai2"},"display":{"title":"Clostridium difficile and its toxins","abstract":"An investigation of Clostridium difficile has shown : 1. that the organism is resistant to cresols and phenolq and may be grown from material grossly contaminated with other organisms by culture in media containing these substances; strains isolated before this method was evised are also resistant to cresols and phenol; 2. that the organism divides into four daughter cells; 3. that each strain examined has a different strain specific agglutinogen, and that the strains are otherwise antigenically complex; 4. that the sugar reactions are fairly consistent 5. that gelatin is liquefied by all available strains in three weeks; and that apart from this there is no proteolytic activity 6. that the hyaluronidase produced by all strains is antigenically uniform? and so is the lethal toxin; 7. and that the 'haemolysin' is almost certainly complex.","abstract_html":"An investigation of Clostridium difficile has shown : 1. that the organism is resistant to cresols and phenolq and may be grown from material grossly contaminated with other organisms by culture in media containing these substances; strains isolated before this method was evised are also resistant to cresols and phenol; 2. that the organism divides into four daughter cells; 3. that each strain examined has a different strain specific agglutinogen, and that the strains are otherwise antigenically complex; 4. that the sugar reactions are fairly consistent 5. that gelatin is liquefied by all available strains in three weeks; and that apart from this there is no proteolytic activity 6. that the hyaluronidase produced by all strains is antigenically uniform? and so is the lethal toxin; 7. and that the 'haemolysin' is almost certainly complex.","abstract_has_math":false,"creators":["Hafiz, Saleem"],"institution":"University of Leeds","degree_name":"Ph.D","degree_level":"doctoral","degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1974,"date_issued":"1974","date_published":"1974","updated_at":"2026-07-24T06:03:54Z","subjects":[],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["uk.bl.ethos.490383"],"render_values":[{"text":"uk.bl.ethos.490383","href":null,"code":true}]}]},"links":{"outbound_url":null,"outbound_label":null,"outbound_source":null},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Hafiz, Saleem"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["1974"]},{"key":"dc:date.issued","label":"Date","values":["1974"]},{"key":"dc:publisher.commercial","label":"Dc Publisher Commercial","values":["University of Leeds"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Faculty of Biological Sciences (Leeds)"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Leeds"]},{"key":"dc:relation.isreferencedby","label":"Dc Relation Isreferencedby","values":["https://etheses.whiterose.ac.uk/id/eprint/972/"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["doctoral"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["Ph.D"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["uk.bl.ethos.490383"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://etheses.whiterose.ac.uk/id/eprint/972/1/uk_bl_ethos_490383.pdf"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["An investigation of Clostridium difficile has shown : 1. that the organism is resistant to cresols and phenolq and may be grown from material grossly contaminated with other organisms by culture in media containing these substances; strains isolated before this method was evised are also resistant to cresols and phenol; 2. that the organism divides into four daughter cells; 3. that each strain examined has a different strain specific agglutinogen, and that the strains are otherwise antigenically complex; 4. that the sugar reactions are fairly consistent 5. that gelatin is liquefied by all available strains in three weeks; and that apart from this there is no proteolytic activity 6. that the hyaluronidase produced by all strains is antigenically uniform? and so is the lethal toxin; 7. and that the 'haemolysin' is almost certainly complex."]},{"key":"dc:format","label":"Dc Format","values":["text"]},{"key":"dc:title","label":"Title","values":["Clostridium difficile and its toxins"]}]}],"canonical_facts":{"dc:creator":["Hafiz, Saleem"],"dc:date":["1974"],"dc:date.issued":["1974"],"dc:description.abstract":["An investigation of Clostridium difficile has shown : 1. that the organism is resistant to cresols and phenolq and may be grown from material grossly contaminated with other organisms by culture in media containing these substances; strains isolated before this method was evised are also resistant to cresols and phenol; 2. that the organism divides into four daughter cells; 3. that each strain examined has a different strain specific agglutinogen, and that the strains are otherwise antigenically complex; 4. that the sugar reactions are fairly consistent 5. that gelatin is liquefied by all available strains in three weeks; and that apart from this there is no proteolytic activity 6. that the hyaluronidase produced by all strains is antigenically uniform? 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