{"id":{"repo_id":"wfu","oai_identifier":"oai:wakespace.lib.wfu.edu:10339/93050"},"canonical_url":"https://search.dev.ndltd.org/etd/wfu/oai:wakespace.lib.wfu.edu:10339/93050","repository":{"repo_id":"wfu","name":"Wake Forest University","base_url":"https://wakespace.lib.wfu.edu/oai/request"},"display":{"title":"Investigation of Adiposity Phenotypes in AA Associated With GALNT10 & Related Pathway Genes","abstract":"The overall goal of this project is to verify previous findings in the GALNT10 region and to expand our knowledge of this locus via genomic association studies in obesity-related traits, comparison to expression quantitative trait loci (eQTL) data, and a mouse knockout model, in addition to furthering our knowledge of genes in the pathway in which GALNT10 acts. Previously, genome-wide association studies in African Americans (AA) have identified common variants upstream of GALNT10 locus for association with body mass index (BMI). These studies encompassed a small number of variants upstream of GALNT10 that were common, noncoding variants, as is typically seen in GWAS studies.","abstract_html":"The overall goal of this project is to verify previous findings in the GALNT10 region and to expand our knowledge of this locus via genomic association studies in obesity-related traits, comparison to expression quantitative trait loci (eQTL) data, and a mouse knockout model, in addition to furthering our knowledge of genes in the pathway in which GALNT10 acts. Previously, genome-wide association studies in African Americans (AA) have identified common variants upstream of GALNT10 locus for association with body mass index (BMI). These studies encompassed a small number of variants upstream of GALNT10 that were common, noncoding variants, as is typically seen in GWAS studies.","abstract_has_math":false,"creators":["Stromberg, Mary"],"institution":"Wake Forest University","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2018,"date_issued":"2018","date_published":"2018","updated_at":"2026-07-27T22:02:23Z","subjects":[],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10339/93050","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Stromberg, Mary"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2019-01-11T09:35:17Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2019-01-11T09:35:17Z"]},{"key":"dc:date.issued","label":"Date","values":["2018"]},{"key":"dc:publisher","label":"Institution","values":["Wake Forest University"]},{"key":"dc:type","label":"Dc Type","values":["Dissertation"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10339/93050"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The overall goal of this project is to verify previous findings in the GALNT10 region and to expand our knowledge of this locus via genomic association studies in obesity-related traits, comparison to expression quantitative trait loci (eQTL) data, and a mouse knockout model, in addition to furthering our knowledge of genes in the pathway in which GALNT10 acts. Previously, genome-wide association studies in African Americans (AA) have identified common variants upstream of GALNT10 locus for association with body mass index (BMI). These studies encompassed a small number of variants upstream of GALNT10 that were common, noncoding variants, as is typically seen in GWAS studies."]},{"key":"dc:title","label":"Title","values":["Investigation of Adiposity Phenotypes in AA Associated With GALNT10 & Related Pathway Genes"]}]}],"canonical_facts":{"dc:creator":["Stromberg, Mary"],"dc:date.accessioned":["2019-01-11T09:35:17Z"],"dc:date.available":["2019-01-11T09:35:17Z"],"dc:date.issued":["2018"],"dc:description.abstract":["The overall goal of this project is to verify previous findings in the GALNT10 region and to expand our knowledge of this locus via genomic association studies in obesity-related traits, comparison to expression quantitative trait loci (eQTL) data, and a mouse knockout model, in addition to furthering our knowledge of genes in the pathway in which GALNT10 acts. Previously, genome-wide association studies in African Americans (AA) have identified common variants upstream of GALNT10 locus for association with body mass index (BMI). These studies encompassed a small number of variants upstream of GALNT10 that were common, noncoding variants, as is typically seen in GWAS studies."],"dc:identifier.uri":["http://hdl.handle.net/10339/93050"],"dc:language.iso":["en"],"dc:publisher":["Wake Forest University"],"dc:title":["Investigation of Adiposity Phenotypes in AA Associated With GALNT10 & Related Pathway Genes"],"dc:type":["Dissertation"]},"updated_at":"2026-07-27T22:02:23Z"}