MOLECULAR ANALYSIS OF HYALURONIC ACID (HA) USING SOLID-STATE NANOPORES

Hyaluronic acid (HA; hyaluronan) has emerged as a powerful indicator for a range of diseases and physiological conditions, including cancer, osteoarthritis, and wound healing after injury. Evidence has shown that low molecular weight HA is pro-inflammatory while high molecular weight HA is anti-inflammatory, suggesting the potential importance of HA size as an independent biomarker. However, current methods to measure HA are time consuming, rarely distinguish HA by molecular weight and are not easily integrated in the clinical setting. Thus, there is a need for improved HA detection and quantification methods that can address this need.

Grantor dc:publisher

Wake Forest University

Year dc:date.issued

2017

Author dc:creator

• Rivas Duarte, Felipe

• Biosensor

Language dc:language.iso

en

Handle dc:identifier.uri

http://hdl.handle.net/10339/86345

OAI identifier oai:identifier

oai:wakespace.lib.wfu.edu:10339/86345