{"id":{"repo_id":"wfu","oai_identifier":"oai:wakespace.lib.wfu.edu:10339/57120"},"canonical_url":"https://search.dev.ndltd.org/etd/wfu/oai:wakespace.lib.wfu.edu:10339/57120","repository":{"repo_id":"wfu","name":"Wake Forest University","base_url":"https://wakespace.lib.wfu.edu/oai/request"},"display":{"title":"CHARACTERIZING THE MICRO-SCALE MECHANICAL PROPERTIES OF HYDROGELS AND CANCER CELLS","abstract":"Tissue engineering strategies nowadays require attention to not only cells, but also to the mechanical properties of the extracellular matrix (ECM).We studied the elasticity of hydrogels formulations frequently used in cell and tissue culturing. A variety of concentrations in a variety of biomaterials, including agarose, alginate, the collagens, fibrin, hyaluronic acid, kerateine, laminin, Matrigel, and polyethylene glycol diacrylate (PEGDA), were tested with atomic force microscopy (AFM). We also determined the Young’s modulus (E) of hydrogels with different concentrations. E tended to increase with increased concentration.","abstract_html":"Tissue engineering strategies nowadays require attention to not only cells, but also to the mechanical properties of the extracellular matrix (ECM).We studied the elasticity of hydrogels formulations frequently used in cell and tissue culturing. A variety of concentrations in a variety of biomaterials, including agarose, alginate, the collagens, fibrin, hyaluronic acid, kerateine, laminin, Matrigel, and polyethylene glycol diacrylate (PEGDA), were tested with atomic force microscopy (AFM). We also determined the Young’s modulus (E) of hydrogels with different concentrations. E tended to increase with increased concentration.","abstract_has_math":false,"creators":["Guo, Xinyi"],"institution":"Wake Forest University","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015","date_published":"2015","updated_at":"2026-07-27T22:01:52Z","subjects":["Atomic Force Microscopy"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10339/57120","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Guo, Xinyi"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2015-06-23T08:35:43Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2015-06-23T08:35:43Z"]},{"key":"dc:date.issued","label":"Date","values":["2015"]},{"key":"dc:publisher","label":"Institution","values":["Wake Forest University"]},{"key":"dc:type","label":"Dc Type","values":["Dissertation"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Atomic Force Microscopy"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10339/57120"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Tissue engineering strategies nowadays require attention to not only cells, but also to the mechanical properties of the extracellular matrix (ECM).We studied the elasticity of hydrogels formulations frequently used in cell and tissue culturing. A variety of concentrations in a variety of biomaterials, including agarose, alginate, the collagens, fibrin, hyaluronic acid, kerateine, laminin, Matrigel, and polyethylene glycol diacrylate (PEGDA), were tested with atomic force microscopy (AFM). We also determined the Young’s modulus (E) of hydrogels with different concentrations. E tended to increase with increased concentration."]},{"key":"dc:title","label":"Title","values":["CHARACTERIZING THE MICRO-SCALE MECHANICAL PROPERTIES OF HYDROGELS AND CANCER CELLS"]}]}],"canonical_facts":{"dc:creator":["Guo, Xinyi"],"dc:date.accessioned":["2015-06-23T08:35:43Z"],"dc:date.available":["2015-06-23T08:35:43Z"],"dc:date.issued":["2015"],"dc:description.abstract":["Tissue engineering strategies nowadays require attention to not only cells, but also to the mechanical properties of the extracellular matrix (ECM).We studied the elasticity of hydrogels formulations frequently used in cell and tissue culturing. A variety of concentrations in a variety of biomaterials, including agarose, alginate, the collagens, fibrin, hyaluronic acid, kerateine, laminin, Matrigel, and polyethylene glycol diacrylate (PEGDA), were tested with atomic force microscopy (AFM). We also determined the Young’s modulus (E) of hydrogels with different concentrations. E tended to increase with increased concentration."],"dc:identifier.uri":["http://hdl.handle.net/10339/57120"],"dc:language.iso":["en"],"dc:publisher":["Wake Forest University"],"dc:subject":["Atomic Force Microscopy"],"dc:title":["CHARACTERIZING THE MICRO-SCALE MECHANICAL PROPERTIES OF HYDROGELS AND CANCER CELLS"],"dc:type":["Dissertation"]},"updated_at":"2026-07-27T22:01:52Z"}