Blood Pressure Regulation by the Endocannabinoid System in Conditions Associated with Hypertension

Hypertension is associated with various conditions including obesity, type II diabetes and aging. Despite decades of research, the mechanisms involved in the development of hypertension are still poorly understood. Emerging evidence suggests hypertension is mediated by an imbalance in autonomic nervous system activity. Baroreflex sensitivity for control of heart rate, an important index of vagus nerve function as well as general morbidity and mortality, is often impaired in conditions associated with hypertension. Restoration of baroreflex function is now recognized as a therapeutic strategy for prevention of cardiovascular diseases. Therefore, it is crucial to identify key factors that regulate brainstem regions controlling autonomic outflow in conditions associated with baroreflex dysfunction.

Grantor dc:publisher

Wake Forest University

Year dc:date.issued

2014

Author dc:creator

• Schaich, Chris

• Autonomic Nervous System

Language dc:language.iso

en

Handle dc:identifier.uri

http://hdl.handle.net/10339/39330

OAI identifier oai:identifier

oai:wakespace.lib.wfu.edu:10339/39330