{"id":{"repo_id":"wfu","oai_identifier":"oai:wakespace.lib.wfu.edu:10339/39329"},"canonical_url":"https://search.dev.ndltd.org/etd/wfu/oai:wakespace.lib.wfu.edu:10339/39329","repository":{"repo_id":"wfu","name":"Wake Forest University","base_url":"https://wakespace.lib.wfu.edu/oai/request"},"display":{"title":"Ethosuximide, a T-type Calcium Channel Antagonist, Reduces Alcohol Withdrawal Seizure","abstract":"Alcohol is the third highest risk factor for health related problems in the world and leads to over two million deaths per year. Individuals abusing alcohol frequently cycle between drinking and withdrawal states, which among other adverse side effects can induce withdrawal seizures. Alcohol withdrawal seizures are a major component of relapse and represent a significant barrier to recovery. Unfortunately, alcohol withdrawal seizures can cause more serious consequences such as status epilepticus and temporal lobe epilepsy, severe life-threatening conditions that often result in death.","abstract_html":"Alcohol is the third highest risk factor for health related problems in the world and leads to over two million deaths per year. Individuals abusing alcohol frequently cycle between drinking and withdrawal states, which among other adverse side effects can induce withdrawal seizures. Alcohol withdrawal seizures are a major component of relapse and represent a significant barrier to recovery. Unfortunately, alcohol withdrawal seizures can cause more serious consequences such as status epilepticus and temporal lobe epilepsy, severe life-threatening conditions that often result in death.","abstract_has_math":false,"creators":["Riegle, Melissa Ann"],"institution":"Wake Forest University","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2014,"date_issued":"2014","date_published":"2014","updated_at":"2026-07-27T22:01:46Z","subjects":["alcohol"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10339/39329","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Riegle, Melissa Ann"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-07-10T08:35:43Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2015-07-10T08:30:11Z"]},{"key":"dc:date.issued","label":"Date","values":["2014"]},{"key":"dc:publisher","label":"Institution","values":["Wake Forest University"]},{"key":"dc:type","label":"Dc Type","values":["Dissertation"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["alcohol"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10339/39329"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Alcohol is the third highest risk factor for health related problems in the world and leads to over two million deaths per year. Individuals abusing alcohol frequently cycle between drinking and withdrawal states, which among other adverse side effects can induce withdrawal seizures. Alcohol withdrawal seizures are a major component of relapse and represent a significant barrier to recovery. Unfortunately, alcohol withdrawal seizures can cause more serious consequences such as status epilepticus and temporal lobe epilepsy, severe life-threatening conditions that often result in death."]},{"key":"dc:title","label":"Title","values":["Ethosuximide, a T-type Calcium Channel Antagonist, Reduces Alcohol Withdrawal Seizure"]}]}],"canonical_facts":{"dc:creator":["Riegle, Melissa Ann"],"dc:date.accessioned":["2014-07-10T08:35:43Z"],"dc:date.available":["2015-07-10T08:30:11Z"],"dc:date.issued":["2014"],"dc:description.abstract":["Alcohol is the third highest risk factor for health related problems in the world and leads to over two million deaths per year. Individuals abusing alcohol frequently cycle between drinking and withdrawal states, which among other adverse side effects can induce withdrawal seizures. Alcohol withdrawal seizures are a major component of relapse and represent a significant barrier to recovery. Unfortunately, alcohol withdrawal seizures can cause more serious consequences such as status epilepticus and temporal lobe epilepsy, severe life-threatening conditions that often result in death."],"dc:identifier.uri":["http://hdl.handle.net/10339/39329"],"dc:language.iso":["en"],"dc:publisher":["Wake Forest University"],"dc:subject":["alcohol"],"dc:title":["Ethosuximide, a T-type Calcium Channel Antagonist, Reduces Alcohol Withdrawal Seizure"],"dc:type":["Dissertation"]},"updated_at":"2026-07-27T22:01:46Z"}