{"id":{"repo_id":"wfu","oai_identifier":"oai:wakespace.lib.wfu.edu:10339/37262"},"canonical_url":"https://search.dev.ndltd.org/etd/wfu/oai:wakespace.lib.wfu.edu:10339/37262","repository":{"repo_id":"wfu","name":"Wake Forest University","base_url":"https://wakespace.lib.wfu.edu/oai/request"},"display":{"title":"Neurological Mechanisms Underlying Rotator Cuff Skeletal Muscle Pathophysiology and Implications for Therapy","abstract":"Introduction: Rotator cuff tears are a common cause of upper-extremity disability. For chronic, full-thickness, rotator cuff tears, repair surgery can be technically challenging due to large gap distances and increased stiffness of the muscle-tendon unit. In contrast, acute rotator cuff tears are associated with lower repair tensions, less fibro-fatty infiltration of the muscle, and better functional outcomes. Animal models can be used to understand rotator cuff muscle function and these results can be translated into clinical recommendations using computational modeling.","abstract_html":"Introduction: Rotator cuff tears are a common cause of upper-extremity disability. For chronic, full-thickness, rotator cuff tears, repair surgery can be technically challenging due to large gap distances and increased stiffness of the muscle-tendon unit. In contrast, acute rotator cuff tears are associated with lower repair tensions, less fibro-fatty infiltration of the muscle, and better functional outcomes. Animal models can be used to understand rotator cuff muscle function and these results can be translated into clinical recommendations using computational modeling.","abstract_has_math":false,"creators":["Mannava, Sandeep"],"institution":"Wake Forest University","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2012,"date_issued":"2012","date_published":"2012","updated_at":"2026-07-27T22:01:27Z","subjects":["botulinum neurotoxin A"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10339/37262","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Mannava, Sandeep"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2012-06-12T08:35:50Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2012-06-12T08:35:50Z"]},{"key":"dc:date.issued","label":"Date","values":["2012"]},{"key":"dc:publisher","label":"Institution","values":["Wake Forest University"]},{"key":"dc:type","label":"Dc Type","values":["Dissertation"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["botulinum neurotoxin A"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10339/37262"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Introduction: Rotator cuff tears are a common cause of upper-extremity disability. For chronic, full-thickness, rotator cuff tears, repair surgery can be technically challenging due to large gap distances and increased stiffness of the muscle-tendon unit. In contrast, acute rotator cuff tears are associated with lower repair tensions, less fibro-fatty infiltration of the muscle, and better functional outcomes. Animal models can be used to understand rotator cuff muscle function and these results can be translated into clinical recommendations using computational modeling."]},{"key":"dc:title","label":"Title","values":["Neurological Mechanisms Underlying Rotator Cuff Skeletal Muscle Pathophysiology and Implications for Therapy"]}]}],"canonical_facts":{"dc:creator":["Mannava, Sandeep"],"dc:date.accessioned":["2012-06-12T08:35:50Z"],"dc:date.available":["2012-06-12T08:35:50Z"],"dc:date.issued":["2012"],"dc:description.abstract":["Introduction: Rotator cuff tears are a common cause of upper-extremity disability. For chronic, full-thickness, rotator cuff tears, repair surgery can be technically challenging due to large gap distances and increased stiffness of the muscle-tendon unit. In contrast, acute rotator cuff tears are associated with lower repair tensions, less fibro-fatty infiltration of the muscle, and better functional outcomes. Animal models can be used to understand rotator cuff muscle function and these results can be translated into clinical recommendations using computational modeling."],"dc:identifier.uri":["http://hdl.handle.net/10339/37262"],"dc:language.iso":["en"],"dc:publisher":["Wake Forest University"],"dc:subject":["botulinum neurotoxin A"],"dc:title":["Neurological Mechanisms Underlying Rotator Cuff Skeletal Muscle Pathophysiology and Implications for Therapy"],"dc:type":["Dissertation"]},"updated_at":"2026-07-27T22:01:27Z"}