Induction of Neutrophil Extracellular Traps by Nontypeable Haemophilus Influenzae And Defense Mechanisms Against Host NETs and Oxidative Stress
type: CreativeWork
description: Nontypeable Haemophilus influenzae (NTHi) is a Gram-negative commensal bacteria of the human nasopharynx. Normally residing in healthy individuals, NTHi rarely causes adverse effects. However, infection with NTHi in children often leads to middle ear inflammation and disease in the form of otitis media. A high frequency of doctor visits, antibiotic prescription, and drainage tube placement are due to childhood otitis media infections. Chronic obstructive pulmonary disease (COPD) is a restriction of airflow through the lungs and is often caused by cigarette smoking. In the United States, COPD is the fourth leading cause of death. NTHi is often found in patients suffering from COPD and it is implicated in exacerbation of disease. Since these diseases remain a health-care concern, it is important that we continue to study NTHi disease dynamics and host responses during the disease.
abstract: Nontypeable Haemophilus influenzae (NTHi) is a Gram-negative commensal bacteria of the human nasopharynx. Normally residing in healthy individuals, NTHi rarely causes adverse effects. However, infection with NTHi in children often leads to middle ear inflammation and disease in the form of otitis media. A high frequency of doctor visits, antibiotic prescription, and drainage tube placement are due to childhood otitis media infections. Chronic obstructive pulmonary disease (COPD) is a restriction of airflow through the lungs and is often caused by cigarette smoking. In the United States, COPD is the fourth leading cause of death. NTHi is often found in patients suffering from COPD and it is implicated in exacerbation of disease. Since these diseases remain a health-care concern, it is important that we continue to study NTHi disease dynamics and host responses during the disease.
author: Juneau, Richard Anthony
language: en
keywords: COPD
date published: 2011
date modified: 2026-07-27T22:01:20Z
provider: Wake Forest University
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: Wake Forest University

PropertyValue
property ID: Handle
value: http://hdl.handle.net/10339/36165