{"id":{"repo_id":"wfu","oai_identifier":"oai:wakespace.lib.wfu.edu:10339/36150"},"canonical_url":"https://search.dev.ndltd.org/etd/wfu/oai:wakespace.lib.wfu.edu:10339/36150","repository":{"repo_id":"wfu","name":"Wake Forest University","base_url":"https://wakespace.lib.wfu.edu/oai/request"},"display":{"title":"ETHICAL CONSIDERATIONS OF THE USE OF INVESTIGATIONAL NEW DRUGS DURING THE GULF WAR","abstract":"At the onset of the Gulf War in 1992, the threat of chemical and biological weapons prompted the Department of Defense to seek a waiver from the Food and Drug Administration to use the investigational new drugs pyridostigmine bromide and botulism vaccine without first obtaining consent from those servicemen and women who would receive the drugs. The waiver was granted and came in the form of the Interim Rule, which permitted the use of investigational new drugs when consent could not be obtained because of \"non-feasibility\" and the nature of the military mission. The Interim Rule restricted the soldiers' rights to informed consent, but was it justified?","abstract_html":"At the onset of the Gulf War in 1992, the threat of chemical and biological weapons prompted the Department of Defense to seek a waiver from the Food and Drug Administration to use the investigational new drugs pyridostigmine bromide and botulism vaccine without first obtaining consent from those servicemen and women who would receive the drugs. The waiver was granted and came in the form of the Interim Rule, which permitted the use of investigational new drugs when consent could not be obtained because of "non-feasibility" and the nature of the military mission. The Interim Rule restricted the soldiers' rights to informed consent, but was it justified?","abstract_has_math":false,"creators":["Ghaffar, Sajid"],"institution":"Wake Forest University","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2011,"date_issued":"2011","date_published":"2011","updated_at":"2026-07-27T22:01:20Z","subjects":["Gulf War"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10339/36150","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Ghaffar, Sajid"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2011-09-08T08:35:58Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2011-09-08T08:35:58Z"]},{"key":"dc:date.issued","label":"Date","values":["2011"]},{"key":"dc:publisher","label":"Institution","values":["Wake Forest University"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Gulf War"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10339/36150"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["At the onset of the Gulf War in 1992, the threat of chemical and biological weapons prompted the Department of Defense to seek a waiver from the Food and Drug Administration to use the investigational new drugs pyridostigmine bromide and botulism vaccine without first obtaining consent from those servicemen and women who would receive the drugs. The waiver was granted and came in the form of the Interim Rule, which permitted the use of investigational new drugs when consent could not be obtained because of \"non-feasibility\" and the nature of the military mission. The Interim Rule restricted the soldiers' rights to informed consent, but was it justified?"]},{"key":"dc:title","label":"Title","values":["ETHICAL CONSIDERATIONS OF THE USE OF INVESTIGATIONAL NEW DRUGS DURING THE GULF WAR"]}]}],"canonical_facts":{"dc:creator":["Ghaffar, Sajid"],"dc:date.accessioned":["2011-09-08T08:35:58Z"],"dc:date.available":["2011-09-08T08:35:58Z"],"dc:date.issued":["2011"],"dc:description.abstract":["At the onset of the Gulf War in 1992, the threat of chemical and biological weapons prompted the Department of Defense to seek a waiver from the Food and Drug Administration to use the investigational new drugs pyridostigmine bromide and botulism vaccine without first obtaining consent from those servicemen and women who would receive the drugs. The waiver was granted and came in the form of the Interim Rule, which permitted the use of investigational new drugs when consent could not be obtained because of \"non-feasibility\" and the nature of the military mission. The Interim Rule restricted the soldiers' rights to informed consent, but was it justified?"],"dc:identifier.uri":["http://hdl.handle.net/10339/36150"],"dc:language.iso":["en"],"dc:publisher":["Wake Forest University"],"dc:subject":["Gulf War"],"dc:title":["ETHICAL CONSIDERATIONS OF THE USE OF INVESTIGATIONAL NEW DRUGS DURING THE GULF WAR"],"dc:type":["Thesis"]},"updated_at":"2026-07-27T22:01:20Z"}