{"id":{"repo_id":"wfu","oai_identifier":"oai:wakespace.lib.wfu.edu:10339/33425"},"canonical_url":"https://search.dev.ndltd.org/etd/wfu/oai:wakespace.lib.wfu.edu:10339/33425","repository":{"repo_id":"wfu","name":"Wake Forest University","base_url":"https://wakespace.lib.wfu.edu/oai/request"},"display":{"title":"In situ bioprinting of the skin","abstract":"Burn injury is a common source of morbidity and mortality in the battlefield, comprising 10 to 30% of all casualties. In the civilian population, there are approximately 500,000 burn injuries requiring treatment each year. Autografts and commercially available skin products are limited in size and some require a lengthy preparation time, making them unusable in severe cases that require prompt and aggressive measures to maintain the lives of wounded patients. Moreover, patient survival is inversely proportional to the amount of time required to cover and stabilize a wound. Therefore, a new approach that permits immediate burn wound stabilization with functional recovery is necessary. We propose a novel treatment that would repair burn wounds in situ by using cartridge-based bioprinting to precisely deliver skin cells in a controlled manner in a wound.","abstract_html":"Burn injury is a common source of morbidity and mortality in the battlefield, comprising 10 to 30% of all casualties. In the civilian population, there are approximately 500,000 burn injuries requiring treatment each year. Autografts and commercially available skin products are limited in size and some require a lengthy preparation time, making them unusable in severe cases that require prompt and aggressive measures to maintain the lives of wounded patients. Moreover, patient survival is inversely proportional to the amount of time required to cover and stabilize a wound. Therefore, a new approach that permits immediate burn wound stabilization with functional recovery is necessary. We propose a novel treatment that would repair burn wounds <italic>in situ</italic> by using cartridge-based bioprinting to precisely deliver skin cells in a controlled manner in a wound.","abstract_has_math":false,"creators":["Binder, Kyle"],"institution":"Wake Forest University","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2011,"date_issued":"2011","date_published":"2011","updated_at":"2026-07-27T22:01:14Z","subjects":["bioprinting"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10339/33425","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Binder, Kyle"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2011-07-14T20:35:03Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2012-07-14T08:30:18Z"]},{"key":"dc:date.issued","label":"Date","values":["2011"]},{"key":"dc:publisher","label":"Institution","values":["Wake Forest University"]},{"key":"dc:type","label":"Dc Type","values":["Dissertation"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["bioprinting"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10339/33425"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Burn injury is a common source of morbidity and mortality in the battlefield, comprising 10 to 30% of all casualties. In the civilian population, there are approximately 500,000 burn injuries requiring treatment each year. Autografts and commercially available skin products are limited in size and some require a lengthy preparation time, making them unusable in severe cases that require prompt and aggressive measures to maintain the lives of wounded patients. Moreover, patient survival is inversely proportional to the amount of time required to cover and stabilize a wound. Therefore, a new approach that permits immediate burn wound stabilization with functional recovery is necessary. We propose a novel treatment that would repair burn wounds in situ by using cartridge-based bioprinting to precisely deliver skin cells in a controlled manner in a wound."]},{"key":"dc:title","label":"Title","values":["In situ bioprinting of the skin"]}]}],"canonical_facts":{"dc:creator":["Binder, Kyle"],"dc:date.accessioned":["2011-07-14T20:35:03Z"],"dc:date.available":["2012-07-14T08:30:18Z"],"dc:date.issued":["2011"],"dc:description.abstract":["Burn injury is a common source of morbidity and mortality in the battlefield, comprising 10 to 30% of all casualties. In the civilian population, there are approximately 500,000 burn injuries requiring treatment each year. Autografts and commercially available skin products are limited in size and some require a lengthy preparation time, making them unusable in severe cases that require prompt and aggressive measures to maintain the lives of wounded patients. Moreover, patient survival is inversely proportional to the amount of time required to cover and stabilize a wound. Therefore, a new approach that permits immediate burn wound stabilization with functional recovery is necessary. We propose a novel treatment that would repair burn wounds in situ by using cartridge-based bioprinting to precisely deliver skin cells in a controlled manner in a wound."],"dc:identifier.uri":["http://hdl.handle.net/10339/33425"],"dc:language.iso":["en"],"dc:publisher":["Wake Forest University"],"dc:subject":["bioprinting"],"dc:title":["In situ bioprinting of the skin"],"dc:type":["Dissertation"]},"updated_at":"2026-07-27T22:01:14Z"}