KINESIN-MICROTUBULE INTERACTIONS DURING GLIDING ASSAYS UNDER MAGNETIC FORCE

Conventional kinesin is a motor protein capable of converting the chemical energy of ATP into mechanical work. In the cell, this is used to actively transport vesicles through the intracellular matrix. The relationship between the velocity of a single kinesin, as it works against an increasing opposing load, has been well studied. The relationship between the velocity of a cargo being moved by multiple kinesin motors against an opposing load has not been established. A major difficulty in determining the force-velocity relationship for multiple motors is determining the number of motors that are moving a cargo against an opposing load.

Grantor dc:publisher

Wake Forest University

Year dc:date.issued

2010

Author dc:creator

• Fallesen, Todd Landon

• kinesin

Language dc:language.iso

en

Handle dc:identifier.uri

http://hdl.handle.net/10339/30429

OAI identifier oai:identifier

oai:wakespace.lib.wfu.edu:10339/30429