Study of behaviour of Biomechanical System in indented Articular Cartilage on a cellular level
type: CreativeWork
description: The study of biomechanical systems is of great interest to researches due to diverse applications in the medical sector. This study focuses on design and implementation of a mechanical device, a novel dual axis construct simulator (DACS) for in vitro studies on immortalised chondrocytes. DACS will help with experimental measurements of mechanical properties of Articular Cartilage (AC) on a cellular level and the relationship among cellular, pericellular and extracellular deformation in AC. Details provided in this research mainly focuses on software and hardware development processes and challenges involved. There will a brief introduction about biomechanical behaviour of the cartilage and DACS impact on future studies. This will be followed by description of LCMPilot, an experimental software and challenges involved to develop and control DACS in an automated setup.
abstract: The study of biomechanical systems is of great interest to researches due to diverse applications in the medical sector. This study focuses on design and implementation of a mechanical device, a novel dual axis construct simulator (DACS) for in vitro studies on immortalised chondrocytes. DACS will help with experimental measurements of mechanical properties of Articular Cartilage (AC) on a cellular level and the relationship among cellular, pericellular and extracellular deformation in AC. Details provided in this research mainly focuses on software and hardware development processes and challenges involved. There will a brief introduction about biomechanical behaviour of the cartilage and DACS impact on future studies. This will be followed by description of LCMPilot, an experimental software and challenges involved to develop and control DACS in an automated setup.
author: Ramezanian Kalahroudi, M.
date published: 2018
date modified: 2026-07-24T06:01:30Z
provider: University of Westminster
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: University of Westminster